Mutations in ABCD1
reference sequence
Region |
Mutation |
|
|
Publications |
Sentences |
MutMiner_hits |
SNAP2 |
PROVEAN |
Effect_ExpVar |
CL0 |
p.Met
1
Val
|
details |
homologous mutations |
2 |
3 |
3 |
N |
N |
? |
CL0 |
p.Asn
13
Thr
|
details |
homologous mutations |
3 |
13 |
13 |
N |
N |
? |
CL0 |
p.Arg
17
His
|
details |
homologous mutations |
1 |
4 |
4 |
N |
N |
? |
CL0 |
p.Arg
17
Trp
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,TH1 |
p.Ala
19
Ser
|
details |
homologous mutations |
1 |
16 |
17 |
N |
N |
? |
TMD1,TH1 |
p.Tyr
33
*
|
details |
homologous mutations |
1 |
1 |
1 |
- |
- |
? |
TMD1,EL1 |
p.Gln
47
*
|
details |
homologous mutations |
1 |
1 |
1 |
- |
- |
? |
TMD1,EL1 |
p.Ala
57
Val
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
TMD1,EL1 |
p.Ala
61
Val
|
details |
homologous mutations |
2 |
6 |
6 |
N |
N |
? |
TMD1,EL1 |
p.Ala
61
Gly
|
details |
homologous mutations |
2 |
4 |
4 |
N |
N |
? |
TMD1,EL1 |
p.Phe
71
Ser
|
details |
homologous mutations |
1 |
1 |
2 |
D |
D |
? |
TMD1,EL1 |
p.Phe
71
Val
|
details |
homologous mutations |
1 |
1 |
2 |
D |
D |
? |
TMD1,EL1 |
p.Arg
74
Trp
|
details |
homologous mutations |
3 |
4 |
7 |
D |
D |
? |
TMD1,EL1 |
p.Arg
74
Cys
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,EL1 |
p.Arg
74
Gly
|
details |
homologous mutations |
1 |
1 |
2 |
D |
D |
? |
TMD1,EL1 |
p.Leu
78
Phe
|
details |
homologous mutations |
2 |
5 |
8 |
D |
D |
? |
TMD1,EL1 |
p.Leu
81
Val
|
details |
homologous mutations |
1 |
1 |
2 |
N |
N |
? |
TMD1,EL1 |
p.Pro
84
Ser
|
details |
homologous mutations |
1 |
1 |
1 |
N |
D |
? |
TMD1,EL1 |
p.Pro
84
Ala
|
details |
homologous mutations |
1 |
1 |
2 |
D |
D |
? |
TMD1,EL1 |
p.Cys
88
Trp
|
details |
homologous mutations |
1 |
4 |
4 |
D |
D |
? |
TMD1,EL1 |
p.Glu
90
Lys
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,EL1 |
p.Ala
95
Asp
|
details |
homologous mutations |
1 |
1 |
1 |
D |
N |
? |
TMD1,TH2 |
p.Ser
98
Leu
|
details |
homologous mutations |
6 |
15 |
18 |
D |
D |
? |
TMD1,TH2 |
p.Ser
98
Trp
|
details |
homologous mutations |
1 |
5 |
5 |
D |
D |
? |
TMD1,TH2 |
p.Ser
98
*
|
details |
homologous mutations |
1 |
1 |
1 |
- |
- |
? |
TMD1,TH2 |
p.Ala
99
Asp
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,TH2 |
p.Val
102
Glu
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,TH2 |
p.Ser
103
Arg
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,TH2 |
p.Arg
104
His
|
details |
homologous mutations |
5 |
13 |
13 |
D |
D |
? |
TMD1,TH2 |
p.Arg
104
Cys
|
details |
homologous mutations |
9 |
41 |
53 |
D |
D |
? |
TMD1,TH2 |
p.Arg
104
Pro
|
details |
homologous mutations |
1 |
7 |
7 |
D |
D |
? |
TMD1,TH2 |
p.Arg
104
Lys
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,TH2 |
p.Thr
105
Ile
|
details |
homologous mutations |
2 |
2 |
2 |
D |
D |
? |
TMD1,TH2 |
p.Leu
107
Pro
|
details |
homologous mutations |
1 |
1 |
2 |
D |
D |
? |
TMD1,TH2 |
p.Ser
108
Trp
|
details |
homologous mutations |
4 |
9 |
10 |
D |
D |
? |
TMD1,TH2 |
p.Ser
108
*
|
details |
homologous mutations |
2 |
7 |
7 |
- |
- |
? |
TMD1,TH2 |
p.Ser
108
Leu
|
details |
homologous mutations |
4 |
11 |
16 |
D |
D |
? |
TMD1,TH2 |
p.Arg
113
Pro
|
details |
homologous mutations |
2 |
6 |
10 |
D |
N |
? |
TMD1,TH2 |
p.Arg
113
Cys
|
details |
homologous mutations |
1 |
1 |
1 |
D |
N |
? |
TMD1,CL1 |
p.Leu
114
Pro
|
details |
homologous mutations |
1 |
3 |
4 |
D |
D |
? |
TMD1,CL1 |
p.Gly
116
Arg
|
details |
homologous mutations |
4 |
31 |
43 |
D |
D |
D |
TMD1,CL1 |
p.Arg
120
Pro
|
details |
homologous mutations |
1 |
4 |
4 |
D |
D |
? |
TMD1,CL1 |
p.Val
123
Ile
|
details |
homologous mutations |
1 |
9 |
12 |
D |
N |
? |
TMD1,CL1 |
p.Gln
133
*
|
details |
homologous mutations |
1 |
1 |
1 |
- |
- |
? |
TMD1,TH3 |
p.Trp
137
*
|
details |
homologous mutations |
3 |
3 |
4 |
- |
- |
? |
TMD1,TH3 |
p.Ala
141
Thr
|
details |
homologous mutations |
6 |
11 |
11 |
D |
D |
D |
TMD1,TH3 |
p.Pro
143
Ser
|
details |
homologous mutations |
3 |
8 |
9 |
D |
D |
? |
TMD1,TH3 |
p.Pro
143
Leu
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,TH3 |
p.Pro
143
His
|
details |
homologous mutations |
1 |
1 |
3 |
D |
D |
? |
TMD1,TH3 |
p.Pro
143
Ala
|
details |
homologous mutations |
1 |
1 |
3 |
D |
D |
? |
TMD1,TH3 |
p.Asn
148
Ser
|
details |
homologous mutations |
6 |
14 |
15 |
D |
D |
D |
TMD1,TH3 |
p.Asn
148
Tyr
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,TH3 |
p.Asn
148
Asp
|
details |
homologous mutations |
2 |
5 |
5 |
D |
D |
? |
TMD1,TH3 |
p.Ser
149
Asn
|
details |
homologous mutations |
5 |
6 |
7 |
D |
D |
? |
TMD1,TH3 |
p.Arg
152
Cys
|
details |
homologous mutations |
6 |
19 |
19 |
D |
D |
? |
TMD1,TH3 |
p.Arg
152
Leu
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,TH3 |
p.Arg
152
Ser
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,TH3 |
p.Arg
152
Pro
|
details |
homologous mutations |
2 |
2 |
2 |
D |
D |
? |
TMD1,EL2 |
p.Leu
154
Pro
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,EL2 |
p.Leu
158
Pro
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,EL2 |
p.Leu
160
Pro
|
details |
homologous mutations |
2 |
12 |
12 |
D |
D |
? |
TMD1,EL2 |
p.Ser
161
Pro
|
details |
homologous mutations |
1 |
1 |
1 |
D |
N |
? |
TMD1,EL2 |
p.Arg
163
Pro
|
details |
homologous mutations |
2 |
5 |
5 |
D |
D |
? |
TMD1,EL2 |
p.Arg
163
His
|
details |
homologous mutations |
2 |
3 |
3 |
D |
D |
? |
TMD1,EL2 |
p.Arg
163
Leu
|
details |
homologous mutations |
1 |
6 |
6 |
D |
D |
? |
TMD1,EL2 |
p.Tyr
174
Cys
|
details |
homologous mutations |
10 |
42 |
50 |
D |
D |
D |
TMD1,EL2 |
p.Tyr
174
Ser
|
details |
homologous mutations |
4 |
17 |
20 |
D |
D |
D |
TMD1,EL2 |
p.Tyr
174
Asp
|
details |
homologous mutations |
2 |
5 |
5 |
D |
D |
D |
TMD1,EL2 |
p.Tyr
174
His
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
D |
TMD1,EL2 |
p.Gln
177
*
|
details |
homologous mutations |
3 |
3 |
5 |
- |
- |
? |
TMD1,EL2 |
p.Gln
178
Arg
|
details |
homologous mutations |
1 |
4 |
4 |
D |
D |
? |
TMD1,EL2 |
p.Gln
178
Glu
|
details |
homologous mutations |
2 |
4 |
4 |
D |
N |
? |
TMD1,EL2 |
p.Gln
178
*
|
details |
homologous mutations |
1 |
2 |
2 |
- |
- |
? |
TMD1,EL2 |
p.Tyr
181
Cys
|
details |
homologous mutations |
3 |
8 |
8 |
D |
D |
? |
TMD1,EL2 |
p.Arg
182
Pro
|
details |
homologous mutations |
3 |
4 |
4 |
D |
D |
? |
TMD1,EL2 |
p.Asp
194
His
|
details |
homologous mutations |
4 |
46 |
52 |
D |
D |
? |
TMD1,EL2 |
p.Gln
195
*
|
details |
homologous mutations |
1 |
1 |
1 |
- |
- |
? |
TMD1,EL2 |
p.Thr
198
Lys
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,EL2 |
p.Thr
198
Met
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,EL2 |
p.Glu
199
Lys
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,EL2 |
p.Asp
200
Val
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,EL2 |
p.Asp
200
Asn
|
details |
homologous mutations |
2 |
2 |
3 |
D |
D |
? |
TMD1,EL2 |
p.His
210
Gln
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,EL2 |
p.Tyr
212
*
|
details |
homologous mutations |
1 |
1 |
1 |
- |
- |
? |
TMD1,EL2 |
p.Ser
213
Cys
|
details |
homologous mutations |
2 |
6 |
6 |
D |
D |
? |
TMD1,EL2 |
p.Asn
214
Asp
|
details |
homologous mutations |
2 |
2 |
3 |
D |
N |
? |
TMD1,EL2 |
p.Lys
217
Glu
|
details |
homologous mutations |
5 |
16 |
18 |
D |
D |
? |
TMD1,EL2 |
p.Pro
218
Thr
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,EL2 |
p.Pro
218
Ser
|
details |
homologous mutations |
1 |
1 |
3 |
D |
D |
? |
TMD1,EL2 |
p.Leu
220
Pro
|
details |
homologous mutations |
6 |
8 |
12 |
D |
D |
? |
TMD1,EL2 |
p.Asp
221
Gly
|
details |
homologous mutations |
1 |
8 |
9 |
D |
D |
? |
TMD1,EL2 |
p.Val
222
Leu
|
details |
homologous mutations |
1 |
1 |
3 |
N |
N |
? |
TMD1,EL2 |
p.Ala
223
Asp
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,EL2 |
p.Val
224
Glu
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,EL2 |
p.Leu
229
Pro
|
details |
homologous mutations |
2 |
7 |
8 |
D |
D |
? |
TMD1,EL2 |
p.Arg
236
His
|
details |
homologous mutations |
1 |
3 |
3 |
D |
D |
|
TMD1,TH4 |
p.Trp
242
*
|
details |
homologous mutations |
2 |
3 |
3 |
- |
- |
? |
TMD1,TH4 |
p.Ala
245
Asp
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,TH4 |
p.Gly
248
Arg
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,TH4 |
p.Thr
254
Pro
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,TH4 |
p.Thr
254
Met
|
details |
homologous mutations |
3 |
3 |
3 |
D |
D |
? |
TMD1,CL2 |
p.Arg
259
Trp
|
details |
homologous mutations |
3 |
13 |
14 |
D |
D |
? |
TMD1,CL2 |
p.Pro
263
Leu
|
details |
homologous mutations |
1 |
3 |
3 |
D |
D |
? |
TMD1,CL2 |
p.Gly
266
Arg
|
details |
homologous mutations |
12 |
30 |
45 |
D |
D |
D |
TMD1,CL2 |
p.Gly
266
Gln
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
D |
TMD1,CL2 |
p.Gly
266
Ala
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
D |
TMD1,CL2 |
p.Glu
271
Lys
|
details |
homologous mutations |
2 |
4 |
5 |
D |
D |
? |
TMD1,CL2 |
p.Arg
274
Trp
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,CL2 |
p.Lys
276
Glu
|
details |
homologous mutations |
3 |
5 |
5 |
D |
D |
? |
TMD1,CL2 |
p.Gly
277
Arg
|
details |
homologous mutations |
3 |
11 |
11 |
D |
D |
? |
TMD1,CL2 |
p.Gly
277
Trp
|
details |
homologous mutations |
2 |
3 |
3 |
D |
D |
? |
TMD1,CL2 |
p.Leu
279
Val
|
details |
homologous mutations |
2 |
3 |
3 |
D |
D |
? |
TMD1,CL2 |
p.Leu
279
Pro
|
details |
homologous mutations |
1 |
2 |
3 |
D |
D |
? |
TMD1,CL2 |
p.Arg
280
Cys
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
D |
TMD1,CL2 |
p.Arg
280
Leu
|
details |
homologous mutations |
1 |
3 |
3 |
D |
D |
D |
TMD1,CL2 |
p.Tyr
281
His
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
TMD1,CL2 |
p.His
283
Arg
|
details |
homologous mutations |
2 |
8 |
8 |
D |
D |
? |
TMD1,CL2 |
p.His
283
Asp
|
details |
homologous mutations |
2 |
3 |
3 |
D |
D |
? |
TMD1,CL2 |
p.His
283
Tyr
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,CL2 |
p.Arg
285
Pro
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,CL2 |
p.Ser
290
*
|
details |
homologous mutations |
1 |
1 |
1 |
- |
- |
? |
TMD1,CL2 |
p.Ser
290
Trp
|
details |
homologous mutations |
2 |
3 |
3 |
D |
D |
? |
TMD1,CL2 |
p.Glu
291
Lys
|
details |
homologous mutations |
2 |
5 |
5 |
D |
D |
D |
TMD1,CL2 |
p.Glu
291
Asp
|
details |
homologous mutations |
2 |
3 |
3 |
D |
D |
D |
TMD1,CL2 |
p.Glu
291
Leu
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
D |
TMD1,CL2 |
p.Glu
291
Ala
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
D |
TMD1,CL2 |
p.Ala
294
Thr
|
details |
homologous mutations |
2 |
4 |
4 |
D |
D |
? |
TMD1,CL2 |
p.Ala
294
Val
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,CL2 |
p.Tyr
296
Cys
|
details |
homologous mutations |
7 |
9 |
13 |
D |
D |
D |
TMD1,CL2 |
p.Gly
298
Asp
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,CL2 |
p.Gly
298
Arg
|
details |
homologous mutations |
1 |
4 |
4 |
D |
D |
? |
TMD1,CL2 |
p.Glu
302
Lys
|
details |
homologous mutations |
1 |
8 |
8 |
D |
D |
? |
TMD1,CL2 |
p.Gln
307
*
|
details |
homologous mutations |
2 |
2 |
4 |
- |
- |
? |
TMD1,CL2 |
p.Leu
313
Pro
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,CL2 |
p.Ala
314
Pro
|
details |
homologous mutations |
1 |
3 |
3 |
N |
D |
? |
TMD1,CL2 |
p.Ser
315
*
|
details |
homologous mutations |
1 |
1 |
1 |
- |
- |
? |
TMD1,CL2 |
p.Leu
322
Pro
|
details |
homologous mutations |
3 |
8 |
9 |
D |
N |
? |
TMD1,CL2 |
p.Leu
325
Pro
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,CL2 |
p.Trp
326
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,CL2 |
p.Lys
336
Met
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,TH5 |
p.Trp
339
Cys
|
details |
homologous mutations |
1 |
6 |
6 |
D |
D |
? |
TMD1,TH5 |
p.Ala
341
Asp
|
details |
homologous mutations |
1 |
11 |
11 |
D |
D |
? |
TMD1,TH5 |
p.Ser
342
Pro
|
details |
homologous mutations |
3 |
20 |
28 |
D |
D |
? |
TMD1,TH5 |
p.Gly
343
Asp
|
details |
homologous mutations |
2 |
2 |
2 |
D |
D |
? |
TMD1,TH5 |
p.Gly
343
Ser
|
details |
homologous mutations |
1 |
3 |
3 |
D |
D |
? |
TMD1,TH5 |
p.Gly
343
Val
|
details |
homologous mutations |
4 |
14 |
14 |
D |
D |
? |
TMD1,EL3 |
p.Ser
358
*
|
details |
homologous mutations |
1 |
2 |
2 |
- |
- |
? |
TMD1,EL3 |
p.Glu
376
Gln
|
details |
homologous mutations |
1 |
7 |
7 |
N |
N |
? |
TMD1,EL3 |
p.Ser
379
Arg
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,EL3 |
p.Arg
389
His
|
details |
homologous mutations |
15 |
32 |
36 |
D |
D |
D |
TMD1,EL3 |
p.Arg
389
Gly
|
details |
homologous mutations |
2 |
2 |
2 |
D |
D |
D |
TMD1,EL3 |
p.Arg
389
Cys
|
details |
homologous mutations |
2 |
2 |
7 |
D |
D |
D |
TMD1,EL3 |
p.Leu
391
Pro
|
details |
homologous mutations |
2 |
6 |
8 |
D |
D |
? |
TMD1,EL3 |
p.Ala
396
Thr
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,EL3 |
p.Arg
401
Gln
|
details |
homologous mutations |
15 |
53 |
57 |
D |
D |
D |
TMD1,EL3 |
p.Arg
401
Trp
|
details |
homologous mutations |
5 |
7 |
8 |
D |
D |
D |
TMD1,EL3 |
p.Arg
401
Gly
|
details |
homologous mutations |
1 |
3 |
3 |
D |
D |
D |
TMD1,EL3 |
p.Ser
404
*
|
details |
homologous mutations |
1 |
1 |
1 |
- |
- |
? |
TMD1,EL3 |
p.Lys
407
*
|
details |
homologous mutations |
1 |
1 |
1 |
- |
- |
? |
TMD1,TH6 |
p.Arg
418
Trp
|
details |
homologous mutations |
4 |
7 |
11 |
D |
D |
D |
TMD1,TH6 |
p.His
420
Pro
|
details |
homologous mutations |
1 |
11 |
11 |
D |
D |
? |
CL3 |
p.Gln
430
*
|
details |
homologous mutations |
1 |
1 |
1 |
- |
- |
D |
CL3 |
p.Lys
435
Met
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
CL3 |
p.Arg
452
Glu
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
CL3 |
p.Glu
458
Ala
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
CL3 |
p.Arg
464
*
|
details |
homologous mutations |
5 |
9 |
10 |
- |
- |
D |
CL3,NBD1 |
p.Ile
474
Thr
|
details |
homologous mutations |
1 |
1 |
1 |
D |
N |
? |
CL3,NBD1 |
p.Cys
476
*
|
details |
homologous mutations |
1 |
2 |
2 |
- |
- |
? |
CL3,NBD1 |
p.Glu
477
*
|
details |
homologous mutations |
1 |
3 |
3 |
- |
- |
D |
CL3,NBD1 |
p.Pro
480
Thr
|
details |
homologous mutations |
1 |
1 |
3 |
D |
D |
? |
CL3,NBD1 |
p.Ile
481
Phe
|
details |
homologous mutations |
1 |
3 |
3 |
D |
D |
? |
CL3,NBD1 |
p.Pro
484
Arg
|
details |
homologous mutations |
6 |
16 |
16 |
D |
D |
D |
CL3,NBD1 |
p.Glu
487
Lys
|
details |
homologous mutations |
2 |
2 |
2 |
D |
D |
? |
CL3,NBD1 |
p.Met
501
Leu
|
details |
homologous mutations |
1 |
2 |
2 |
N |
D |
? |
CL3,NBD1 |
p.Leu
503
Pro
|
details |
homologous mutations |
1 |
3 |
3 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Gly
507
Asp
|
details |
homologous mutations |
1 |
4 |
6 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Gly
507
Val
|
details |
homologous mutations |
1 |
1 |
2 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Pro
508
Leu
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Asn
509
Ile
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Gly
510
Asp
|
details |
homologous mutations |
1 |
4 |
4 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Gly
510
Ser
|
details |
homologous mutations |
2 |
3 |
3 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Cys
511
*
|
details |
homologous mutations |
1 |
1 |
1 |
- |
- |
? |
CL3,NBD1,WA1 |
p.Gly
512
Cys
|
details |
homologous mutations |
1 |
4 |
4 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Gly
512
Ser
|
details |
homologous mutations |
22 |
56 |
57 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Gly
512
Asp
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Lys
513
Gln
|
details |
homologous mutations |
1 |
14 |
14 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Lys
513
Arg
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Ser
514
Asn
|
details |
homologous mutations |
1 |
13 |
15 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Ser
514
Ile
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Ser
514
Arg
|
details |
homologous mutations |
2 |
4 |
4 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Ser
514
His
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Ser
515
Phe
|
details |
homologous mutations |
4 |
17 |
20 |
D |
D |
D |
CL3,NBD1 |
p.Ser
515
Tyr
|
details |
homologous mutations |
1 |
6 |
6 |
D |
D |
? |
CL3,NBD1 |
p.Leu
516
Pro
|
details |
homologous mutations |
1 |
4 |
4 |
D |
D |
? |
CL3,NBD1 |
p.Arg
518
Trp
|
details |
homologous mutations |
8 |
29 |
33 |
D |
D |
D |
CL3,NBD1 |
p.Arg
518
Gln
|
details |
homologous mutations |
15 |
37 |
46 |
D |
D |
D |
CL3,NBD1 |
p.Arg
518
Gly
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
D |
CL3,NBD1 |
p.Gly
522
Trp
|
details |
homologous mutations |
2 |
6 |
6 |
D |
D |
? |
CL3,NBD1 |
p.Leu
523
Phe
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Trp
524
*
|
details |
homologous mutations |
1 |
2 |
2 |
- |
- |
? |
CL3,NBD1 |
p.Tyr
527
*
|
details |
homologous mutations |
1 |
1 |
1 |
- |
- |
? |
CL3,NBD1 |
p.Lys
533
Glu
|
details |
homologous mutations |
1 |
2 |
4 |
D |
D |
? |
CL3,NBD1 |
p.Pro
534
Leu
|
details |
homologous mutations |
1 |
4 |
6 |
D |
D |
? |
CL3,NBD1 |
p.Pro
534
Arg
|
details |
homologous mutations |
2 |
5 |
5 |
D |
D |
? |
CL3,NBD1 |
p.Phe
540
Ser
|
details |
homologous mutations |
3 |
4 |
5 |
D |
D |
? |
CL3,NBD1 |
p.Phe
540
Cys
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Pro
543
Leu
|
details |
homologous mutations |
6 |
13 |
18 |
D |
D |
? |
CL3,NBD1 |
p.Gln
544
Arg
|
details |
homologous mutations |
6 |
31 |
43 |
D |
D |
? |
CL3,NBD1 |
p.Arg
545
Trp
|
details |
homologous mutations |
1 |
3 |
4 |
D |
D |
? |
CL3,NBD1 |
p.Tyr
547
Cys
|
details |
homologous mutations |
1 |
11 |
11 |
D |
D |
? |
CL3,NBD1 |
p.Arg
554
His
|
details |
homologous mutations |
12 |
26 |
31 |
D |
D |
D |
CL3,NBD1 |
p.Gln
556
Arg
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
CL3,NBD1 |
p.Ile
558
Thr
|
details |
homologous mutations |
1 |
8 |
8 |
D |
D |
? |
CL3,NBD1 |
p.Tyr
559
His
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Tyr
559
Cys
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Pro
560
Leu
|
details |
homologous mutations |
15 |
53 |
67 |
D |
D |
D |
CL3,NBD1 |
p.Pro
560
Ser
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Asp
561
Val
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
CL3,NBD1 |
p.Met
566
Lys
|
details |
homologous mutations |
2 |
2 |
2 |
D |
D |
? |
CL3,NBD1 |
p.Gln
567
*
|
details |
homologous mutations |
1 |
2 |
2 |
- |
- |
? |
CL3,NBD1 |
p.Ser
572
*
|
details |
homologous mutations |
1 |
2 |
2 |
- |
- |
? |
CL3,NBD1 |
p.Gln
574
*
|
details |
homologous mutations |
1 |
3 |
4 |
- |
- |
? |
CL3,NBD1 |
p.Leu
576
Pro
|
details |
homologous mutations |
2 |
5 |
5 |
D |
D |
? |
CL3,NBD1 |
p.Leu
585
Pro
|
details |
homologous mutations |
1 |
4 |
6 |
D |
D |
? |
CL3,NBD1 |
p.Ile
588
His
|
details |
homologous mutations |
1 |
3 |
3 |
D |
D |
? |
CL3,NBD1 |
p.Arg
591
Pro
|
details |
homologous mutations |
2 |
2 |
2 |
D |
D |
D |
CL3,NBD1 |
p.Arg
591
Gln
|
details |
homologous mutations |
10 |
30 |
31 |
D |
D |
D |
CL3,NBD1 |
p.Arg
591
Trp
|
details |
homologous mutations |
4 |
13 |
15 |
D |
D |
D |
CL3,NBD1 |
p.Trp
595
*
|
details |
homologous mutations |
3 |
4 |
6 |
- |
- |
? |
CL3,NBD1 |
p.Trp
601
*
|
details |
homologous mutations |
1 |
1 |
2 |
- |
- |
D |
CL3,NBD1 |
p.Lys
602
*
|
details |
homologous mutations |
1 |
3 |
3 |
- |
- |
? |
CL3,NBD1,SIG1 |
p.Leu
605
Gln
|
details |
homologous mutations |
1 |
4 |
4 |
D |
D |
? |
CL3,NBD1,SIG1 |
p.Ser
606
Pro
|
details |
homologous mutations |
6 |
42 |
57 |
D |
D |
? |
CL3,NBD1,SIG1 |
p.Ser
606
Leu
|
details |
homologous mutations |
19 |
85 |
105 |
D |
D |
D |
CL3,NBD1,SIG1 |
p.Ser
606
His
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1,SIG1 |
p.Gly
607
Asp
|
details |
homologous mutations |
1 |
3 |
3 |
D |
D |
? |
CL3,NBD1,SIG1 |
p.Gly
608
Asp
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1,SIG1 |
p.Gly
608
Ser
|
details |
homologous mutations |
2 |
2 |
2 |
D |
D |
? |
CL3,NBD1,SIG1 |
p.Glu
609
Lys
|
details |
homologous mutations |
8 |
19 |
21 |
D |
D |
D |
CL3,NBD1,SIG1 |
p.Glu
609
Gly
|
details |
homologous mutations |
3 |
10 |
10 |
D |
D |
D |
CL3,NBD1,SIG1 |
p.Ala
616
Asp
|
details |
homologous mutations |
2 |
3 |
3 |
D |
D |
? |
CL3,NBD1,SIG1 |
p.Ala
616
Thr
|
details |
homologous mutations |
2 |
9 |
14 |
D |
D |
? |
CL3,NBD1,SIG1 |
p.Ala
616
Val
|
details |
homologous mutations |
2 |
2 |
2 |
D |
D |
? |
CL3,NBD1,SIG1 |
p.Arg
617
Cys
|
details |
homologous mutations |
9 |
16 |
18 |
D |
D |
D |
CL3,NBD1,SIG1 |
p.Arg
617
His
|
details |
homologous mutations |
21 |
71 |
85 |
D |
D |
D |
CL3,NBD1,SIG1 |
p.Arg
617
Leu
|
details |
homologous mutations |
2 |
3 |
3 |
D |
D |
D |
CL3,NBD1,SIG1 |
p.Arg
617
Ser
|
details |
homologous mutations |
1 |
11 |
12 |
D |
D |
D |
CL3,NBD1,SIG1 |
p.Arg
617
Gly
|
details |
homologous mutations |
5 |
14 |
20 |
D |
D |
D |
CL3,NBD1 |
p.Tyr
620
His
|
details |
homologous mutations |
1 |
15 |
20 |
D |
D |
? |
CL3,NBD1 |
p.Pro
623
Leu
|
details |
homologous mutations |
1 |
3 |
3 |
D |
D |
? |
CL3,NBD1,WB1 |
p.Ala
626
Thr
|
details |
homologous mutations |
10 |
18 |
23 |
D |
D |
? |
CL3,NBD1,WB1 |
p.Ala
626
Asp
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1,WB1 |
p.Leu
628
Glu
|
details |
homologous mutations |
1 |
3 |
3 |
D |
D |
? |
CL3,NBD1,WB1 |
p.Asp
629
His
|
details |
homologous mutations |
2 |
3 |
3 |
D |
D |
? |
CL3,NBD1 |
p.Glu
630
Gly
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Glu
630
Lys
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Cys
631
Tyr
|
details |
homologous mutations |
2 |
2 |
2 |
D |
D |
? |
CL3,NBD1 |
p.Thr
632
Ile
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Thr
632
Pro
|
details |
homologous mutations |
3 |
3 |
3 |
D |
D |
? |
CL3,NBD1 |
p.Ser
633
Arg
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
CL3,NBD1 |
p.Ser
633
Ile
|
details |
homologous mutations |
2 |
2 |
2 |
D |
D |
? |
CL3,NBD1 |
p.Val
635
Met
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Glu
640
Lys
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Gln
645
*
|
details |
homologous mutations |
1 |
2 |
2 |
- |
- |
? |
CL3,NBD1 |
p.Leu
654
Pro
|
details |
homologous mutations |
4 |
7 |
8 |
D |
D |
? |
CL3,NBD1 |
p.Leu
655
Pro
|
details |
homologous mutations |
1 |
3 |
4 |
D |
D |
? |
CL3,NBD1 |
p.Ser
656
Phe
|
details |
homologous mutations |
1 |
2 |
4 |
D |
D |
? |
CL3,NBD1 |
p.Thr
658
Ala
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Arg
660
Trp
|
details |
homologous mutations |
18 |
44 |
51 |
D |
D |
? |
CL3,NBD1 |
p.Arg
660
Gln
|
details |
homologous mutations |
2 |
15 |
16 |
D |
D |
? |
CL3,NBD1 |
p.Arg
660
Pro
|
details |
homologous mutations |
2 |
2 |
2 |
D |
D |
? |
CL3,NBD1 |
p.Leu
663
Ala
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Trp
664
*
|
details |
homologous mutations |
1 |
1 |
1 |
- |
- |
? |
CL3,NBD1 |
p.Tyr
666
Ser
|
details |
homologous mutations |
1 |
1 |
2 |
D |
D |
? |
CL3,NBD1 |
p.His
667
Asp
|
details |
homologous mutations |
6 |
52 |
72 |
D |
D |
? |
CL3,NBD1 |
p.His
667
Asn
|
details |
homologous mutations |
2 |
3 |
4 |
D |
D |
? |
CL3,NBD1 |
p.His
667
Leu
|
details |
homologous mutations |
1 |
5 |
6 |
D |
D |
? |
CL3,NBD1 |
p.Thr
668
Ile
|
details |
homologous mutations |
2 |
2 |
2 |
D |
D |
? |
CL3,NBD1 |
p.His
669
Tyr
|
details |
homologous mutations |
1 |
1 |
2 |
N |
D |
? |
CL3,NBD1 |
p.His
669
Arg
|
details |
homologous mutations |
3 |
15 |
17 |
N |
D |
? |
CL3,NBD1 |
p.Gln
672
*
|
details |
homologous mutations |
2 |
4 |
4 |
- |
- |
? |
CL3,NBD1 |
p.Phe
673
Ala
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Gly
677
Asp
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
CL3,NBD1 |
p.Trp
679
Arg
|
details |
homologous mutations |
1 |
7 |
7 |
D |
D |
? |
CL3,NBD1 |
p.Leu
684
Pro
|
details |
homologous mutations |
1 |
6 |
6 |
D |
D |
? |
CL3,NBD1 |
p.Thr
693
Met
|
details |
homologous mutations |
2 |
7 |
7 |
D |
N |
? |