Mutations in ABCG2

reference sequence

Region Mutation
Publications
Sentences
MutMiner_hits
SNAP2
PROVEAN
Effect_ExpVar
CL0 p.Ser    2 Ala details homologous mutations 1 1 1 N N ?
CL0 p.Val   12 Met details homologous mutations 146 660 725 N N
CL0 p.Val   12 Asn details homologous mutations 2 4 4 D N ?
CL0 p.Ser   13 Leu details homologous mutations 1 6 7 D N ?
CL0 p.Ala   24 Val details homologous mutations 5 5 5 N N ?
CL0 p.Ser   25 Pro details homologous mutations 1 1 1 N N ?
CL0,NBD1 p.Cys   43 Ser details homologous mutations 1 4 4 N N ?
CL0,NBD1 p.Cys   43 Ala details homologous mutations 2 3 3 N N ?
CL0,NBD1 p.Gly   51 Cys details homologous mutations 16 33 35 N D ?
CL0,NBD1 p.Cys   55 Ser details homologous mutations 1 4 4 N N ?
CL0,NBD1 p.Cys   55 Ala details homologous mutations 2 2 2 N N ?
CL0,NBD1,WA1 p.Thr   82 Ala details homologous mutations 2 3 3 D D ?
CL0,NBD1,WA1 p.Lys   86 Ile details homologous mutations 2 4 4 D D ?
CL0,NBD1,WA1 p.Lys   86 Met details homologous mutations 34 228 261 D D ?
CL0,NBD1,WA1 p.Lys   86 Ala details homologous mutations 1 4 4 D D ?
CL0,NBD1 p.Cys  119 Ser details homologous mutations 1 1 1 D D ?
CL0,NBD1 p.Cys  119 Ala details homologous mutations 1 1 1 D D ?
CL0,NBD1 p.Gln  126 * details homologous mutations 62 282 309 - -
CL0,NBD1 p.Gln  126 Thr details homologous mutations 1 2 2 D D ?
CL0,NBD1 p.Gln  126 * details homologous mutations 25 61 63 - -
CL0,NBD1 p.Gln  126 Lys details homologous mutations 1 1 1 D D ?
CL0,NBD1 p.Met  131 Ala details homologous mutations 1 5 6 D D ?
CL0,NBD1 p.Gln  141 Lys details homologous mutations 307 1934 2302 D N
CL0,NBD1 p.Ala  149 Pro details homologous mutations 14 26 26 N N ?
CL0,NBD1 p.Thr  153 Met details homologous mutations 20 52 54 N N ?
CL0,NBD1 p.His  155 Ala details homologous mutations 1 3 7 N D ?
CL0,NBD1 p.Arg  160 Gln details homologous mutations 9 15 17 D N ?
CL0,NBD1 p.Arg  163 Lys details homologous mutations 14 26 26 N N ?
CL0,NBD1 p.Gln  166 Glu details homologous mutations 34 67 70 N N ?
CL0,NBD1,SIG1 p.Ser  187 Thr details homologous mutations 2 19 23 D D ?
CL0,NBD1,SIG1 p.Ser  187 Ala details homologous mutations 2 9 9 D D ?
CL0,NBD1,SIG1 p.Gly  188 Glu details homologous mutations 3 12 15 D D ?
CL0,NBD1,SIG1 p.Arg  191 Gln details homologous mutations 1 2 2 D D ?
CL0,NBD1,SIG1 p.Arg  193 Lys details homologous mutations 2 5 7 D N ?
CL0,NBD1,SIG1 p.Ser  195 Ala details homologous mutations 1 2 2 N D ?
CL0,NBD1,WB1 p.Ile  206 Leu details homologous mutations 44 129 138 D N ?
CL0,NBD1,WB1 p.Ile  206 Thr details homologous mutations 1 2 2 D D ?
CL0,NBD1,WB1 p.Ile  206 Ser details homologous mutations 1 2 2 D D ?
CL0,NBD1,WB1 p.Ile  206 Asn details homologous mutations 1 2 2 D D ?
CL0,NBD1,WB1 p.Phe  208 Ser details homologous mutations 43 277 321 D D ?
CL0,NBD1,WB1 p.Asp  210 Asn details homologous mutations 4 28 38 D D ?
CL0,NBD1 p.Glu  211 Gln details homologous mutations 6 75 113 D D ?
CL0,NBD1 p.Arg  236 * details homologous mutations 1 1 1 - -
CL0,NBD1 p.Thr  237 Val details homologous mutations 1 3 3 D D ?
CL0,NBD1 p.Ile  239 Lys details homologous mutations 1 3 3 D D ?
CL0,NBD1 p.Ser  248 Pro details homologous mutations 31 108 116 D D ?
CL0,NBD1 p.Ser  248 Thr details homologous mutations 1 1 1 D D ?
CL0,NBD1 p.Ser  248 Phe details homologous mutations 1 3 3 D D ?
CL0,NBD1 p.Gly  268 Arg details homologous mutations 5 14 14 D D ?
CL0,NBD1 p.Pro  269 Ser details homologous mutations 22 77 84 D D ?
CL0,NBD1 p.Cys  284 Ser details homologous mutations 1 4 4 D D ?
CL0,NBD1 p.Cys  284 Ala details homologous mutations 1 9 11 D D ?
CL0 p.Asp  296 His details homologous mutations 4 4 4 D D ?
CL0 p.Arg  309 Gly details homologous mutations 2 2 2 N N ?
CL0 p.Glu  334 * details homologous mutations 20 48 50 - - ?
CL0 p.Ala  347 Thr details homologous mutations 1 1 1 N N ?
CL0 p.Gly  354 Arg details homologous mutations 1 6 7 D N ?
CL0 p.Thr  362 Ala details homologous mutations 3 32 40 N N ?
CL0 p.Thr  362 Asp details homologous mutations 1 11 11 N N ?
CL0 p.Cys  374 Ser details homologous mutations 1 1 1 N D ?
CL0 p.Cys  374 Ala details homologous mutations 1 5 7 N D ?
CL0 p.Arg  383 Ala details homologous mutations 2 44 45 D D ?
CL0 p.Arg  383 Gly details homologous mutations 1 20 22 D D ?
CL0 p.Arg  383 Lys details homologous mutations 1 8 8 D D ?
CL0 p.Arg  383 His details homologous mutations 1 2 2 D D ?
CL0 p.Ser  384 Arg details homologous mutations 1 3 3 D D ?
CL0 p.Asn  387 Ala details homologous mutations 1 20 21 D D ?
CL0 p.Pro  392 Ala details homologous mutations 2 23 23 D D ?
TMD1,TH1 p.Gln  398 Ala details homologous mutations 1 19 20 D D ?
TMD1,TH1 p.Thr  402 Leu details homologous mutations 5 39 47 D N ?
TMD1,TH1 p.Thr  402 Arg details homologous mutations 4 56 67 D D ?
TMD1,TH1 p.Thr  402 Ala details homologous mutations 1 37 38 D N ?
TMD1,TH1 p.Gly  406 Leu details homologous mutations 10 66 93 D D ?
TMD1,TH1 p.Gly  406 Ala details homologous mutations 3 9 12 N N ?
TMD1,TH1 p.Gly  410 Leu details homologous mutations 10 67 90 D D ?
TMD1,TH1 p.Gly  410 Ala details homologous mutations 3 9 12 D D ?
TMD1,TH1 p.Tyr  413 Ser details homologous mutations 1 36 38 D D ?
TMD1,EL1 p.Asn  418 Gln details homologous mutations 1 7 7 D D ?
TMD1,EL1 p.Asn  418 Ala details homologous mutations 2 8 11 D D ?
TMD1,EL1 p.Arg  426 Ala details homologous mutations 1 1 1 D D ?
TMD1,TH2 p.Phe  431 Leu details homologous mutations 36 171 198 D D ?
TMD1,TH2 p.Phe  431 Ser details homologous mutations 2 4 5 D D ?
TMD1,TH2 p.Cys  438 Ser details homologous mutations 1 7 7 D D ?
TMD1,TH2 p.Cys  438 Ala details homologous mutations 1 5 5 D D ?
TMD1,TH2 p.Ser  441 Asn details homologous mutations 51 331 367 D N ?
TMD1,TH2 p.Ser  441 Leu details homologous mutations 1 1 1 D D ?
TMD1,TH2 p.Glu  446 Asp details homologous mutations 1 2 2 D N ?
TMD1,TH2 p.Glu  446 Gly details homologous mutations 1 2 2 D D ?
TMD1,TH2 p.Glu  446 Ala details homologous mutations 1 1 1 D D ?
TMD1,CL1 p.Lys  452 Ala details homologous mutations 3 32 35 D D ?
TMD1,CL1 p.Lys  453 Asp details homologous mutations 1 30 39 D D ?
TMD1,CL1 p.Lys  453 Ala details homologous mutations 2 3 3 N D ?
TMD1,CL1 p.His  457 Ala details homologous mutations 3 40 44 D D ?
TMD1,CL1 p.Tyr  459 Cys details homologous mutations 2 2 2 D D ?
TMD1,CL1 p.Tyr  459 Ser details homologous mutations 1 2 2 D D ?
TMD1,CL1 p.Arg  465 Ala details homologous mutations 2 29 36 D D ?
TMD1,CL1 p.Arg  465 Asp details homologous mutations 1 1 1 D D ?
TMD1,CL1 p.Tyr  469 Phe details homologous mutations 1 5 5 D D ?
TMD1,CL1 p.Tyr  469 Ser details homologous mutations 1 6 7 D D ?
TMD1,CL1 p.Lys  473 Ala details homologous mutations 3 30 30 D D ?
TMD1,CL1 p.Lys  473 Glu details homologous mutations 1 1 1 D D ?
TMD1,CL1 p.Lys  473 Trp details homologous mutations 1 3 3 D D ?
TMD1,TH3 p.Pro  480 Ala details homologous mutations 1 4 4 D D ?
TMD1,TH3 p.Arg  482 Thr details homologous mutations 154 675 758 D D ?
TMD1,TH3 p.Arg  482 Gly details homologous mutations 174 771 832 D D ?
TMD1,TH3 p.Arg  482 Ser details homologous mutations 14 46 50 D D ?
TMD1,TH3 p.Arg  482 Met details homologous mutations 17 33 38 D D ?
TMD1,TH3 p.Arg  482 Ala details homologous mutations 4 7 7 D D ?
TMD1,TH3 p.Arg  482 Lys details homologous mutations 7 63 64 D D ?
TMD1,TH3 p.Arg  482 Trp details homologous mutations 1 6 8 D D ?
TMD1,TH3 p.Arg  482 Asp details homologous mutations 3 10 10 D D ?
TMD1,TH3 p.Arg  482 Tyr details homologous mutations 6 23 23 D D ?
TMD1,TH3 p.Arg  482 Val details homologous mutations 1 2 2 D D ?
TMD1,TH3 p.Arg  482 Cys details homologous mutations 1 2 2 D D ?
TMD1,TH3 p.Arg  482 Glu details homologous mutations 1 2 2 D D ?
TMD1,TH3 p.Arg  482 Asn details homologous mutations 3 4 4 D D ?
TMD1,TH3 p.Arg  482 Gln details homologous mutations 1 2 2 D D ?
TMD1,TH3 p.Arg  482 His details homologous mutations 2 15 15 D D ?
TMD1,TH3 p.Arg  482 Ile details homologous mutations 3 13 13 D D ?
TMD1,TH3 p.Arg  482 Pro details homologous mutations 1 9 9 D D ?
TMD1,TH3 p.Arg  482 Leu details homologous mutations 1 1 1 D D ?
TMD1,TH3 p.Arg  482 Phe details homologous mutations 1 1 1 D D ?
TMD1,TH3 p.Pro  485 Ala details homologous mutations 3 38 40 D D ?
TMD1,TH3 p.Phe  489 Leu details homologous mutations 38 152 163 D D ?
TMD1,TH3 p.Cys  491 Ser details homologous mutations 1 1 1 N D ?
TMD1,TH3 p.Cys  491 Ala details homologous mutations 1 1 1 N D ?
TMD1,EL2 p.Pro  501 Ala details homologous mutations 1 4 4 D D ?
TMD1,TH4 p.Phe  506 Ser details homologous mutations 3 4 4 D D ?
TMD1,TH4 p.Phe  507 Ser details homologous mutations 1 1 1 D D ?
TMD1,TH4 p.Val  508 Leu details homologous mutations 3 5 5 N N ?
TMD1,TH4 p.Met  509 * details homologous mutations 1 1 1 - - ?
TMD1,TH4 p.Leu  525 Arg details homologous mutations 1 1 1 D D ?
TMD1,TH4 p.Ala  528 Thr details homologous mutations 3 3 3 D N ?
TMD1,TH5 p.Thr  542 Ala details homologous mutations 2 2 2 D N ?
TMD1,TH5 p.Cys  544 Ser details homologous mutations 1 2 2 N N ?
TMD1,TH5 p.Cys  544 Ala details homologous mutations 1 1 1 N N ?
TMD1,TH5 p.Met  549 Ala details homologous mutations 1 9 9 D D ?
TMD1,TH5 p.Ser  552 Met details homologous mutations 1 2 2 D D ?
TMD1,TH5 p.Gly  553 Leu details homologous mutations 5 61 71 D D ?
TMD1,TH5 p.Gly  553 Glu details homologous mutations 5 17 17 D D ?
TMD1,TH5 p.Gly  553 Arg details homologous mutations 1 1 1 D D ?
TMD1,TH5 p.Leu  554 Pro details homologous mutations 10 13 13 D D ?
TMD1,TH5 p.Leu  555 Ala details homologous mutations 1 21 28 D N ?
TMD1,TH5 p.Val  556 Ser details homologous mutations 1 4 4 D D ?
TMD1,TH5 p.Asn  557 Asp details homologous mutations 9 17 19 D D ?
TMD1,TH5 p.Asn  557 Glu details homologous mutations 5 7 7 D D ?
TMD1,TH5 p.Asn  557 Arg details homologous mutations 2 5 5 D D ?
TMD1,TH5 p.Asn  557 His details homologous mutations 2 5 5 D N ?
TMD1,TH5 p.Asn  557 Gln details homologous mutations 1 7 7 D D ?
TMD1,TH5 p.Asn  557 Ala details homologous mutations 2 11 15 D D ?
TMD1,TH5 p.Leu  558 Ala details homologous mutations 2 32 40 D D ?
TMD1,EL3 p.Trp  564 Ala details homologous mutations 1 2 2 D D ?
TMD1,EL3 p.Tyr  570 Ser details homologous mutations 1 4 4 D D ?
TMD1,EL3 p.Phe  571 Ile details homologous mutations 13 21 23 D N ?
TMD1,EL3 p.Phe  571 Leu details homologous mutations 3 3 3 D N ?
TMD1,EL3 p.Ile  573 Ala details homologous mutations 1 25 32 D D ?
TMD1,EL3 p.Pro  574 Ala details homologous mutations 1 4 4 N D ?
TMD1,EL3 p.Arg  575 * details homologous mutations 9 11 11 - - ?
TMD1,EL3 p.His  583 Ala details homologous mutations 1 5 5 D D ?
TMD1,EL3 p.Asn  590 Tyr details homologous mutations 42 129 139 D D ?
TMD1,EL3 p.Asn  590 Leu details homologous mutations 1 1 1 D D ?
TMD1,EL3 p.Cys  592 Ala details homologous mutations 8 69 90 D D ?
TMD1,EL3 p.Cys  592 Ser details homologous mutations 5 35 46 D D ?
TMD1,EL3 p.Cys  592 Gly details homologous mutations 8 65 68 D D ?
TMD1,EL3 p.Asn  596 Gln details homologous mutations 12 164 196 D D ?
TMD1,EL3 p.Asn  596 Ala details homologous mutations 3 12 12 D D ?
TMD1,EL3 p.Cys  603 Ala details homologous mutations 12 149 204 D D ?
TMD1,EL3 p.Cys  603 Ser details homologous mutations 5 58 74 D D ?
TMD1,EL3 p.Cys  603 Tyr details homologous mutations 1 2 2 D D ?
TMD1,EL3 p.Cys  603 His details homologous mutations 1 1 1 D D ?
TMD1,EL3 p.Cys  603 Arg details homologous mutations 1 1 1 D D ?
TMD1,EL3 p.Cys  603 Trp details homologous mutations 1 1 1 D D ?
TMD1,EL3 p.Cys  603 Gly details homologous mutations 7 16 16 D D ?
TMD1,EL3 p.Cys  603 Asp details homologous mutations 1 1 1 D D ?
TMD1,EL3 p.Tyr  605 Cys details homologous mutations 1 1 1 D D ?
TMD1,EL3 p.Tyr  605 Ala details homologous mutations 1 1 1 D D ?
TMD1,EL3 p.Cys  608 Ala details homologous mutations 7 72 90 D D ?
TMD1,EL3 p.Cys  608 Ser details homologous mutations 5 27 34 D D ?
TMD1,EL3 p.Cys  608 Gly details homologous mutations 8 64 67 D D ?
TMD1,EL3 p.Asp  620 Asn details homologous mutations 40 145 159 D D ?
TMD1,EL3 p.Pro  623 Ala details homologous mutations 1 4 4 N N ?
TMD1,EL3 p.Asn  629 Ala details homologous mutations 1 22 22 D D ?
TMD1,EL3 p.His  630 Leu details homologous mutations 3 12 12 N D ?
TMD1,EL3 p.His  630 Glu details homologous mutations 5 12 12 N D ?
TMD1,EL3 p.His  630 Asp details homologous mutations 1 1 1 N D ?
TMD1,EL3 p.His  630 Ser details homologous mutations 1 1 1 N D ?
TMD1,EL3 p.His  630 Arg details homologous mutations 1 2 2 N D ?
TMD1,EL3 p.His  630 Lys details homologous mutations 1 2 2 N D ?
TMD1,TH6 p.Ala  632 Val details homologous mutations 3 3 3 N D ?
TMD1,TH6 p.Cys  635 Ser details homologous mutations 1 2 2 N D ?
TMD1,TH6 p.Cys  635 Ala details homologous mutations 1 1 1 N D ?
TMD1,TH6 p.Thr  642 Ala details homologous mutations 1 13 13 N N ?
TMD1,TH6 p.Tyr  645 Phe details homologous mutations 2 21 21 N N ?
TMD1,TH6 p.Tyr  645 Ser details homologous mutations 1 5 5 D D ?
CL3 p.Lys  652 Gln details homologous mutations 1 1 1 N D ?