Mutations at homologous positions to ABCC8 p.Ser1386

Alignment: ABCC_full, Alignment of full length ABCC proteins, 2016-02-18 11:19:27

Mutations exactly at the same position:

		SNAP2 PROVEAN Effect_dbs
ABCC8	p.Ser1386Pro details	D D ?
ABCC6	p.Ser1307Pro details	D D D
ABCC7	p.Thr1252Pro details	D D

Mutations +/- 5 a.a. around the position:

ABCC8	p.Gly1381Ser details p.Lys1384Met details p.Lys1384Arg details p.Lys1384Ala details	D D ? D D ? D D ? D D ?
ABCC1	p.Ala1331Cys details p.Lys1333Met details p.Lys1333Leu details p.Lys1333Arg details p.Lys1333Glu details p.Ser1334Asn details p.Ser1334Asp details p.Ser1334Ala details p.Ser1334Cys details p.Ser1334Thr details p.Ser1334His details p.Thr1337Ala details	D D ? D D ? D D ? D D ? D D ? D D ? D D ? D D ? D D ? D D ? D D ? N D ?
ABCC4	p.Lys1081Asn details p.Leu1084Lys details	D D ? D D ?
ABCC5	p.Ala1239Thr details	N D ?
ABCC6	p.Gly1302Arg details p.Ala1303Pro details p.Gly1311Glu details	D D D N D D D D D
ABCC7	p.Gly1247Arg details p.Gly1247Asp details p.Gly1247* details p.Ser1248Phe details p.Ser1248Cys details p.Ser1248Ala details p.Gly1249Glu details p.Gly1249Arg details p.Lys1250Ala details p.Lys1250Met details p.Lys1250Arg details p.Lys1250Gln details p.Lys1250Cys details p.Lys1250Thr details p.Lys1250Gly details p.Ser1251Asn details p.Ser1251Ala details p.Leu1254* details p.Leu1254Ala details p.Ser1255Pro details p.Ser1255* details p.Ser1255Leu details p.Phe1257Leu details	D D D D ? - - ? D D ? D N ? N N ? D D D D D D D ? D D ? D D ? D D ? D D ? D D ? D D ? N N D D N ? - - N N ? N N D - - D D N N N N
ABCC9	p.Lys1352Arg details	D D ?

The alignment around the queried position:

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

1694
ABCC8 1347

Q

N

L

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Y

D

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1426
ABCC1 1296

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Y

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D

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1375
ABCC2 1303

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Y

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1382
ABCC3 1292

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1371
ABCC4 1044

D

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1122
ABCC5 1196

E

N

A

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1275
ABCC6 1268

R

D

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1347
ABCC7 1213

K

D

L

T

A

K

Y

T

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N

A

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-

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A

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1291
ABCC9 1315

H

D

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1394
ABCC10 1249

Q

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1328
ABCC11 1144

Q

D

Y

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M

K

Y

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D

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1223
ABCC12 1123

R

D

Y

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M

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Y

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D

N

T

P

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1202

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