Mutations at homologous positions to ABCC8 p.Ala309

Alignment: ABCC_full, Alignment of full length ABCC proteins, 2016-02-18 11:19:27

Mutations exactly at the same position:

		SNAP2 PROVEAN Effect_dbs
ABCC8	p.Ala309Gly details	N N ?
ABCC1	p.His335Glu details p.His335Leu details p.His335Gln details p.His335Asp details	D D ? D D ? N N ? D D ?
ABCC7	p.Gly91Arg details p.Gly91Glu details p.Gly91Cys details p.Gly91Ala details	D D D D N D D D D D N D

Mutations +/- 5 a.a. around the position:

ABCC8	p.Arg306His details p.Asp310Asn details	N D ? D D ?
ABCC1	p.Lys332Asp details p.Lys332Leu details p.Lys332Arg details p.Asp336Arg details p.Asp336Leu details p.Asp336Glu details p.Asp336Lys details	D D ? N D ? N N ? D D ? D D ? D D ? D D ?
ABCC2	p.Lys329Ala details p.Lys329Arg details p.Asp333Gly details	D D ? D N ? D D ?
ABCC6	p.Ser317Arg details p.Ile319Val details	D N D N N D
ABCC7	p.Phe87Ile details p.Phe87Leu details p.Phe87Cys details p.Leu88* details p.Leu88Ser details p.Tyr89Cys details p.Leu90Ser details p.Glu92Lys details p.Glu92* details p.Glu92Ala details p.Glu92Asn details p.Glu92Cys details p.Thr94Ser details p.Thr94Ile details p.Lys95Asp details p.Lys95Gln details p.Lys95Arg details p.Lys95Glu details p.Lys95Met details p.Lys95Cys details p.Lys95Ala details p.Lys95Ser details p.Lys95His details p.Ala96Glu details p.Ala96Val details p.Ala96Cys details	D N D N D D ? - - N N N D D N N D D - - D D D D D N D D D D N N ? D N ? D N ? D N ? N N ? D N ? D N ? D D ? D N ? D N ? D N ? D N N N ? N N ?

The alignment around the queried position:

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

400
ABCC8 284

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349
ABCC1 306

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T

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357
ABCC2 293

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354
ABCC3 293

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N

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P

M

343
ABCC4 78

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128
ABCC5 167

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212
ABCC6 294

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P

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343
ABCC7 69

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D

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114
ABCC9 282

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345
ABCC10 273

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317
ABCC11 151

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ABCC12 111

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156

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