ABCC8 p.Ala294Thr
| Predicted by SNAP2: | C: N (78%), D: N (53%), E: N (57%), F: N (82%), G: N (78%), H: D (53%), I: N (82%), K: N (66%), L: N (78%), M: N (78%), N: N (78%), P: N (61%), Q: N (72%), R: N (66%), S: N (93%), T: N (97%), V: N (82%), W: N (53%), Y: D (53%), |
| Predicted by PROVEAN: | C: N, D: D, E: D, F: D, G: N, H: D, I: D, K: D, L: D, M: D, N: D, P: D, Q: D, R: D, S: N, T: N, V: N, W: D, Y: D, |
[switch to compact view]
Comments [show]
None has been submitted yet.
[hide] Isolation and partial characterization of antimicr... J Ind Microbiol Biotechnol. 2007 Jun;34(6):403-12. Epub 2007 Feb 22. Badji B, Mostefaoui A, Sabaou N, Lebrihi A, Mathieu F, Seguin E, Tillequin F
Isolation and partial characterization of antimicrobial compounds from a new strain Nonomuraea sp. NM94.
J Ind Microbiol Biotechnol. 2007 Jun;34(6):403-12. Epub 2007 Feb 22., [PMID:17318487]
Abstract [show]
An actinomycete strain NM94 was isolated from a Saharan soil sample by a dilution agar plating method using chitin-vitamins B medium supplemented with penicillin. The strain presented the morphological and chemical characteristics of the genus Nonomuraea. On the basis of 16S rDNA analysis and physiological tests, this isolate was found to be quite different from the known species of Nonomuraea and might be new. The strain NM94 secreted several antibiotics on yeast extract malt extract glucose medium that were active against some Gram-positive bacteria, yeast, and fungi. The antibiotics were extracted with dichloromethane and detected by bioautography on silica gel plates using Mucor ramannianus and Bacillus subtilis as the test organisms. Among these antibiotics, a complex called 94A showed interesting antifungal activity. It was selected and purified by reverse-phase HPLC. This complex was composed of five compounds. Spectroscopic studies by infrared, mass, and (1)H NMR of the compounds were carried out. Initial results showed that these molecules differed from the known antibiotics produced by other Nonomuraea species.
Comments [show]
None has been submitted yet.
No. Sentence Comment
139 Bar, 0.005 substitutions per nucleotide position N. rubescens A294T (AY039255)98 N. aurea A291T (AY039254)71 70 N. spiralis IFO14097T (MSU48983) 52 N. angiospora IFO13155T (MAU48843) N. pusilla IFO14684T (D85491) NM94 (DQ831042) N. roseola DSM43767T (NRO278221) N. recticatena DSM43937T (NRE404230) N. africana DSM43748T (NAF269555) N. helvata IFO1468T (MHU48975) 85 N. terranata DSM44505T (AF302078) N. rubra DSM43768T (AF277200) N. turkmeniaca DSM43926T (AF277201) 65 N. roseoviolacea IFO14098T (AB039959) N. longicatena NRRL15532T (AB018787) N. salmonea DSM 43678T (X97892) N. kuesteri GW14-1925T (AJ746362)57 77 98 0,005 Table 2 Antimicrobial activities of the strain NM94 The strain NM94 is non-active against the Gram-negative bacteria, Agrobacterium tumefasciens, Escherichia coli ATCC 10536, Klebsiella pneumoniae CIP 82.91, Pseudomonas aeruginosa CIP A22, P. syringae No.
X
ABCC8 p.Ala294Thr 17318487:139:62
status: NEW