Mutations at homologous positions to ABCC7 p.Thr1396
Alignment: ABCC_full, Alignment of full length ABCC proteins, 2016-02-18 11:19:27Mutations exactly at the same position:
|
SNAP2 PROVEAN Effect_dbs |
||
|---|---|---|
| ABCC7 |
p.Thr1396Ala
p.Thr1396Pro
|
D
D
?
D
D
?
|
| ABCC3 |
p.Thr1476Met
|
D
D
?
|
| ABCC8 |
p.Thr1531Ala
|
D
D
?
|
Mutations +/- 5 a.a. around the position:
| ABCC7 |
p.Phe1392Ala
p.Asp1394Ala
p.Asp1394Gly
p.Cys1395*
p.Cys1395Ser
p.Cys1395Tyr
p.Val1397Glu
p.Leu1399*
p.Cys1400*
p.Cys1400Ala
p.Cys1400Ser
p.Glu1401Ala
p.Glu1401*
p.Glu1401Lys
p.Glu1401Gly
|
D
D
?
N
N
?
N
N
?
-
-
?
D
D
?
D
D
?
D
D
-
-
?
-
-
?
N
N
?
N
N
?
N
N
-
-
D
N
N
N
|
| ABCC1 |
p.Cys1479Ala
|
D
D
?
|
| ABCC2 |
p.Ala1492Gly
|
D
D
?
|
| ABCC5 |
p.Thr1383Asn
|
D
D
?
|
| ABCC8 |
p.Arg1530Cys
|
D
D
?
|
The alignment around the queried position:
1839ABCC7 1357
A
S
V
L
S
K
K
L
L
S
L
P
I
R
R
T
K
A
A
I
A
L
V
Q
Q
K
E
R
1436
ABCC1 1441
A
R
A
L
L
R
K
T
K
I
L
V
L
A
T
A
V
D
L
E
T
D
D
L
I
Q
S
T
I
R
T
Q
F
E
D
T
V
L
T
I
A
R
N
T
D
Y
T
R
K
E
Q
Y
A
D
Q
1520
ABCC2 1448
G
R
L
L
R
K
S
K
I
L
V
L
D
E
A
T
A
A
V
D
L
E
T
D
N
L
I
Q
T
I
Q
N
E
F
A
H
C
T
V
I
T
I
H
R
L
H
T
I
M
D
S
D
K
V
M
V
L
D
N
G
K
I
I
E
G
S
P
E
E
L
L
I
P
P
1527
ABCC3 1437
A
R
A
L
L
R
K
S
R
I
L
V
L
D
E
A
T
A
A
I
D
L
E
T
D
N
L
I
Q
A
T
I
R
T
Q
F
D
T
C
V
L
T
I
A
H
R
L
N
T
I
M
D
Y
T
V
L
V
L
D
K
G
V
V
A
E
F
D
S
P
A
N
L
I
A
R
G
I
1516
ABCC4 1188
A
R
A
I
L
R
K
N
Q
I
L
I
I
D
A
T
A
N
V
D
P
R
T
D
E
L
I
Q
K
K
I
E
K
F
A
H
C
T
V
L
T
I
A
H
R
L
N
T
I
I
D
S
D
K
I
M
V
L
D
S
G
R
L
K
E
Y
D
E
P
Y
V
L
L
Q
N
K
E
1267
ABCC5 1341
A
R
A
L
L
R
H
C
K
I
L
I
L
D
E
A
T
A
A
M
D
T
E
T
D
L
L
I
Q
E
T
I
R
E
A
F
A
D
C
T
M
L
I
A
H
R
L
H
T
V
L
S
D
R
I
M
V
L
A
Q
G
Q
V
V
E
F
D
T
P
S
V
L
L
S
N
D
S
S
1420
ABCC6 1413
A
R
A
L
K
T
Q
I
L
L
D
A
T
A
A
V
D
P
G
T
E
L
Q
M
Q
A
M
L
G
S
W
F
A
Q
C
T
V
L
L
I
A
H
L
S
V
M
D
C
A
R
V
L
V
M
D
K
G
Q
V
A
E
S
S
P
A
Q
L
L
A
Q
K
G
L
1492
ABCC8 1492
A
A
F
V
R
K
T
I
F
I
M
A
T
A
S
I
M
A
E
N
I
L
Q
V
M
T
A
F
A
D
V
V
T
I
A
R
V
H
I
S
A
D
L
V
I
K
R
G
I
L
E
F
D
K
E
K
L
S
R
K
D
1571
ABCC9 1460
A
R
F
V
R
K
S
S
I
L
I
M
D
E
A
T
A
S
I
D
M
A
T
E
N
I
L
Q
K
V
V
M
T
A
F
A
D
R
T
V
V
T
I
A
H
R
V
S
S
I
M
D
G
L
V
L
V
F
S
E
G
I
V
E
C
D
T
V
P
N
L
L
A
H
K
N
G
1539
ABCC10 1393
A
R
A
L
L
T
D
A
K
I
L
C
I
D
E
A
T
A
S
V
D
Q
K
T
D
Q
L
L
Q
Q
T
I
C
K
R
F
A
N
K
T
V
L
T
I
A
H
R
L
N
T
I
L
N
S
D
R
V
L
V
L
Q
A
G
R
V
V
E
L
D
S
P
A
L
R
N
Q
P
H
S
1472
ABCC11 1289
A
R
A
V
L
R
N
S
K
I
I
L
I
D
E
A
T
A
S
I
D
M
E
T
D
T
L
I
Q
R
T
I
R
E
A
F
Q
G
C
T
V
L
V
I
A
H
R
V
T
T
V
L
N
C
D
H
I
L
V
M
G
N
G
K
V
V
E
F
D
R
P
E
V
L
R
K
K
P
G
S
1368
ABCC12 1268
A
R
A
L
L
R
N
S
K
I
I
L
L
D
E
A
T
A
S
M
D
S
K
D
T
L
V
Q
N
T
I
K
D
A
F
K
G
C
T
V
L
T
I
A
H
R
L
N
T
V
L
N
C
D
H
V
L
V
M
E
N
G
K
V
I
E
F
D
K
P
E
V
L
A
E
K
P
D
S
1347