Mutations at homologous positions to ABCC7 p.His609
Alignment: ABCC_full, Alignment of full length ABCC proteins, 2016-02-18 11:19:27Mutations exactly at the same position:
|
SNAP2 PROVEAN Effect_dbs |
||
|---|---|---|
| ABCC7 |
p.His609Arg
p.His609*
p.His609Thr
p.His609Leu
|
D
D
-
-
?
D
D
?
D
N
|
Mutations +/- 5 a.a. around the position:
| ABCC7 |
p.Thr604Ala
p.Thr604Ser
p.Ser605Cys
p.Ser605Phe
p.Glu608Gly
p.Leu610Ser
p.Ala613Thr
p.Asp614Gly
|
D
D
?
D
D
D
D
?
D
D
?
D
D
N
D
D
N
D
D
?
|
| ABCC1 |
p.His827Phe
p.His827Leu
p.His827Tyr
p.His827Trp
p.His827Gln
p.His827Asn
p.His827Asp
p.His827Glu
p.Gln834His
|
D
D
?
D
D
?
D
D
?
D
D
?
D
D
?
D
D
?
D
D
?
D
D
?
N
D
?
|
| ABCC3 |
p.Thr809Met
|
D
D
?
|
| ABCC4 |
p.Ala600Pro
|
D
D
?
|
| ABCC6 |
p.Thr811Met
p.Ala820Pro
|
D
D
D
D
D
D
|
| ABCC8 |
p.His888Ala
p.Lys889Thr
|
D
D
?
N
D
?
|
The alignment around the queried position:
ABCC7 570
L
V
V
L
A
N
T
K
M
K
K
I
L
Y
F
Y
F
S
E
Q
N
P
D
F
S
K
L
M
G
C
S
649
ABCC1 792
L
S
A
V
D
A
H
V
G
K
H
I
F
E
N
V
I
G
P
K
G
M
L
K
N
K
T
R
I
L
V
T
S
M
S
Y
L
P
V
D
V
I
I
V
M
S
G
K
I
S
E
G
S
Y
Q
E
L
L
A
R
D
G
F
A
E
F
L
R
T
Y
A
S
871
ABCC2 785
D
P
L
A
V
A
H
V
G
K
H
I
F
K
V
L
G
P
N
L
L
K
G
K
T
R
L
L
V
T
H
S
M
H
F
L
P
Q
V
D
E
I
V
V
L
G
N
G
T
I
V
E
K
G
S
Y
S
A
L
A
K
K
G
E
F
A
K
N
L
K
T
F
L
R
864
ABCC3 775
D
D
P
L
S
A
V
D
S
H
V
A
K
H
I
F
D
H
V
I
G
P
E
G
L
A
G
K
T
R
V
L
V
H
G
I
S
F
L
P
Q
T
D
F
I
I
V
L
A
D
G
Q
S
E
M
G
P
Y
P
A
L
L
Q
R
N
G
S
F
A
N
F
L
C
N
Y
A
P
854
ABCC4 559
D
D
P
L
S
A
V
D
A
E
V
S
R
H
L
F
L
C
I
C
Q
I
-
-
L
H
E
K
I
I
L
V
T
H
Q
L
Q
Y
L
K
A
S
Q
I
L
I
L
K
D
G
K
M
V
Q
K
G
T
Y
T
E
F
L
K
S
G
D
F
G
S
L
L
K
K
D
N
E
636
ABCC5 709
D
D
P
L
S
A
L
D
A
H
V
G
N
H
I
F
N
S
A
I
R
K
H
-
-
L
K
S
K
T
V
L
F
V
T
H
Q
L
Q
Y
L
V
D
C
D
E
V
I
F
M
K
E
G
C
I
T
E
R
G
T
H
E
E
L
M
N
L
N
G
D
Y
A
I
F
N
N
L
L
L
786
ABCC6 777
D
P
L
A
L
D
A
H
G
Q
H
V
F
Q
V
I
G
P
G
G
L
L
Q
G
T
T
I
L
H
A
L
H
I
L
P
Q
D
W
I
I
V
A
N
G
I
A
E
M
G
S
Y
Q
E
L
L
Q
R
K
G
A
L
C
L
D
Q
A
R
Q
856
ABCC8 853
P
F
S
A
L
I
H
L
S
D
H
L
M
Q
A
G
I
L
E
L
L
R
D
D
R
T
V
V
L
V
T
L
Q
Y
L
P
H
A
D
I
I
A
M
K
D
G
I
Q
R
E
G
T
L
K
D
F
R
S
E
C
Q
L
F
E
H
W
K
T
L
M
N
932
ABCC9 836
D
D
P
F
S
A
L
D
I
H
L
S
D
H
L
M
Q
E
G
I
L
K
F
L
Q
D
D
K
R
T
L
V
L
V
T
H
K
L
Q
Y
L
T
H
A
D
W
I
I
A
M
K
D
G
V
L
R
E
G
T
L
K
D
I
Q
T
K
D
V
E
L
Y
E
H
W
K
T
L
M
N
915
ABCC10 750
D
D
P
L
A
A
V
D
A
D
V
A
N
H
L
L
H
R
C
I
L
G
M
L
S
Y
T
T
R
-
-
L
L
C
T
H
R
T
E
Y
L
E
R
A
D
A
V
L
L
M
E
A
G
R
L
I
R
A
G
P
P
S
E
I
L
P
L
V
Q
A
V
P
K
A
W
A
E
N
G
Q
827
ABCC11 658
D
D
P
L
S
A
V
D
A
H
V
G
K
H
I
F
E
E
C
I
K
K
T
-
-
L
R
G
K
T
V
V
L
V
T
H
Q
L
Q
Y
L
E
F
C
G
Q
I
I
L
L
E
N
G
K
I
C
E
N
G
T
H
S
E
L
M
Q
K
K
G
K
Y
A
Q
L
I
Q
K
M
H
-
735
ABCC12 627
D
D
P
L
S
A
V
D
A
H
V
G
K
H
V
F
E
E
C
I
K
K
T
-
-
L
R
G
K
T
V
V
L
V
T
H
Q
L
Q
F
L
E
S
C
D
E
V
I
L
L
E
D
G
E
I
C
E
K
G
T
H
K
E
L
M
E
E
R
G
R
Y
A
K
L
I
H
N
L
R
G
704