Mutations at homologous positions to ABCC8 p.Asn1122

Alignment: ABCC_full, Alignment of full length ABCC proteins, 2016-02-18 11:19:27

Mutations exactly at the same position:

Mutations +/- 5 a.a. around the position:

The alignment around the queried position:

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 1413
ABCC8 1083
V
T
V
E
W
T
G
L
K
V
A
K
R
L
H
R
S
L
L
N
R
I
I
L
A
P
M
R
F
F
E
T
T
P
L
G
S
I
L
N
R
F
S
S
D
C
N
T
I
D
Q
H
I
P
S
T
L
E
C
L
S
R
S
T
L
L
C
V
S
A
L
A
V
I
S
Y
V
T
P
V
 1162
ABCC1 1035
M
A
V
S
I
G
G
I
L
A
S
R
C
L
H
V
D
L
L
H
S
I
L
R
S
P
M
S
F
F
E
R
T
P
S
G
N
L
V
N
R
F
S
K
E
L
D
T
V
D
S
M
I
P
E
V
I
K
M
F
M
G
S
L
F
N
V
I
G
A
C
I
V
I
L
L
A
T
P
I
 1114
ABCC2 1043
F
W
S
A
F
G
F
V
H
A
S
N
I
L
H
K
Q
L
L
N
N
I
L
R
A
P
M
R
F
F
D
T
T
P
T
G
R
I
V
N
R
F
A
G
D
I
S
T
V
D
D
T
L
P
Q
S
L
R
S
W
I
T
C
F
L
G
I
I
S
T
L
V
M
I
C
M
A
T
P
V
 1122
ABCC3 1031
M
A
M
A
A
G
G
I
Q
A
A
R
V
L
H
Q
A
L
L
H
N
K
I
R
S
P
Q
S
F
F
D
T
T
P
S
G
R
I
L
N
C
F
S
K
D
I
Y
V
V
D
E
V
L
A
P
V
I
L
M
L
L
N
S
F
F
N
A
I
S
T
L
V
V
I
M
A
S
T
P
L
 1110
ABCC4 784
L
L
V
F
Y
V
L
V
N
S
S
Q
T
L
H
N
K
M
F
E
S
I
L
K
A
P
V
L
F
F
D
R
N
P
I
G
R
I
L
N
R
F
S
K
D
I
G
H
L
D
D
L
L
P
L
T
F
L
D
F
I
Q
T
L
L
Q
V
V
G
V
V
S
V
A
V
A
V
I
P
W
 863
ABCC5 934
V
V
F
V
K
G
T
L
R
A
S
S
R
L
H
D
E
L
F
R
R
I
L
R
S
P
M
K
F
F
D
T
T
P
T
G
R
I
L
N
R
F
S
K
D
M
D
E
V
D
V
R
L
P
F
Q
A
E
M
F
I
Q
N
V
I
L
V
F
F
C
V
G
M
I
A
G
V
F
P
W
 1013
ABCC6 1007
A
A
V
L
L
G
G
A
R
A
S
R
L
L
F
Q
R
L
L
W
D
V
V
R
S
P
I
S
F
F
E
R
T
P
I
G
H
L
L
N
R
F
S
K
E
T
D
T
V
D
V
D
I
P
D
K
L
R
S
L
L
M
Y
A
F
G
L
L
E
V
S
L
V
V
A
V
A
T
P
L
 1086
ABCC7 935
L
P
L
V
H
T
L
I
T
V
S
K
I
L
H
H
K
M
L
H
S
V
L
Q
A
P
M
S
T
L
N
T
L
K
A
G
G
I
L
N
R
F
S
K
D
I
A
I
L
D
D
L
L
P
L
T
I
F
D
F
I
Q
L
L
L
I
V
I
G
A
I
A
V
V
A
V
L
Q
P
Y
 1014
ABCC9 1055
L
T
V
E
W
M
G
L
T
A
A
K
N
L
H
H
N
L
L
N
K
I
I
L
G
P
I
R
F
F
D
T
T
P
L
G
L
I
L
N
R
F
S
A
D
T
N
I
I
D
Q
H
I
P
P
T
L
E
S
L
T
R
S
T
L
L
C
L
S
A
I
G
M
I
S
Y
A
T
P
V
 1134
ABCC10 987
V
L
F
A
A
G
T
L
Q
A
A
A
T
L
H
R
R
L
L
H
R
V
L
M
A
P
V
T
F
F
N
A
T
P
T
G
R
I
L
N
R
F
S
S
D
V
A
C
A
D
D
S
L
P
F
I
L
N
I
L
L
A
N
A
A
G
L
L
G
L
L
A
V
L
G
S
G
L
P
W
 1066
ABCC11 882
G
I
F
T
K
V
T
R
K
A
S
T
A
L
H
N
K
L
F
N
K
V
F
R
C
P
M
S
F
F
D
T
I
P
I
G
R
L
L
N
C
F
A
G
D
L
E
Q
L
D
Q
L
L
P
I
F
S
E
Q
F
L
V
L
S
L
M
V
I
A
V
L
L
I
V
S
V
L
S
P
Y
 961
ABCC12 871
F
V
F
T
K
T
T
L
M
A
S
S
S
L
H
D
T
V
F
D
K
I
L
K
S
P
M
S
F
F
D
T
T
P
T
G
R
L
M
N
R
F
S
K
D
M
D
E
L
D
V
R
L
P
F
H
A
E
N
F
L
Q
Q
F
F
M
V
V
F
I
L
V
I
L
A
A
V
F
P
A
 950