ABCC1 p.Thr1082Ala

Predicted by SNAP2: A: N (78%), C: N (66%), D: D (63%), E: N (57%), F: N (53%), G: N (72%), H: N (53%), I: N (82%), K: D (63%), L: N (72%), M: N (78%), N: N (61%), P: D (66%), Q: N (57%), R: D (63%), S: N (72%), V: N (93%), W: D (59%), Y: D (63%),
Predicted by PROVEAN: A: N, C: D, D: D, E: D, F: D, G: D, H: D, I: N, K: D, L: N, M: N, N: D, P: D, Q: D, R: D, S: N, V: N, W: D, Y: D,

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[hide] Zhang DW, Gu HM, Situ D, Haimeur A, Cole SP, Deeley RG
Functional importance of polar and charged amino acid residues in transmembrane helix 14 of multidrug resistance protein 1 (MRP1/ABCC1): identification of an aspartate residue critical for conversion from a high to low affinity substrate binding state.
J Biol Chem. 2003 Nov 14;278(46):46052-63. Epub 2003 Sep 3., 2003-11-14 [PMID:12954620]

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