Mutations at homologous positions to ABCC7 p.Lys892
Alignment: ABCC_full, Alignment of full length ABCC proteins, 2016-02-18 11:19:27Mutations exactly at the same position:
|
SNAP2 PROVEAN Effect_dbs |
||
|---|---|---|
| ABCC7 |
p.Lys892Glu
p.Lys892Gln
p.Lys892Cys
|
N
N
?
N
N
?
D
N
?
|
| ABCC4 |
p.Met744Val
|
D
N
?
|
| ABCC9 |
p.Ser1020Pro
|
N
D
D
|
Mutations +/- 5 a.a. around the position:
| ABCC7 |
p.Thr887Pro
p.Gln890*
p.Gln890Arg
p.Asp891Cys
p.Asn894Ala
p.Asn894Gln
p.Asn894Asp
p.Asn894Ser
p.Ser895Thr
p.Ser895Asn
p.Thr896Ile
|
N
N
?
-
-
D
N
N
D
N
?
N
N
?
N
N
?
D
N
?
N
N
?
N
N
?
N
N
D
N
?
|
| ABCC1 |
p.Pro1003Ala
p.Asn1006Gln
|
N
D
?
D
D
?
|
| ABCC11 |
p.Asn838Gln
|
D
D
?
|
| ABCC6 |
p.Trp971Arg
p.Gln981His
|
D
D
?
D
D
D
|
The alignment around the queried position:
ABCC7 853
H
K
S
I
F
V
I
W
L
V
I
F
L
A
V
A
A
L
V
V
L
L
L
G
N
P
L
G
H
S
-
-
-
N
S
A
V
I
I
V
F
V
T
A
M
929
ABCC1 967
M
K
A
I
G
-
L
F
I
S
F
L
S
I
F
L
F
M
N
H
V
S
L
A
S
N
Y
W
L
S
L
W
T
D
D
I
-
-
-
-
-
-
-
-
-
-
-
-
V
G
T
Q
E
H
-
-
-
-
T
K
V
R
L
S
V
Y
G
L
G
I
S
Q
G
I
A
1029
ABCC2 971
L
A
I
G
-
L
F
S
I
F
I
L
A
F
V
M
N
S
V
A
F
I
G
S
N
L
W
L
S
A
W
T
S
D
S
K
-
-
-
-
-
-
-
-
-
-
-
-
I
F
N
S
T
D
Y
P
A
S
R
D
M
G
V
Y
G
A
L
G
L
A
Q
G
F
1037
ABCC3 963
A
K
A
V
G
-
L
C
T
T
L
A
I
C
L
L
Y
V
G
Q
S
A
A
A
I
G
A
N
V
W
L
A
W
T
N
D
A
M
-
-
-
-
-
-
-
-
-
-
-
-
A
D
S
R
Q
N
N
-
-
-
-
T
S
L
R
L
G
V
Y
A
A
L
G
I
L
Q
G
F
L
1025
ABCC4 705
F
R
A
G
A
H
W
I
V
F
I
F
L
I
L
L
N
T
A
A
Q
V
A
Y
V
L
Q
D
W
W
L
S
Y
W
A
N
K
Q
S
L
N
-
-
-
-
-
-
V
T
V
N
G
G
G
N
V
T
K
L
D
L
N
W
Y
L
G
I
Y
S
G
L
T
V
A
T
L
F
778
ABCC5 850
I
Q
A
A
G
G
P
L
A
F
L
V
I
M
A
L
F
M
L
N
V
G
S
T
A
F
S
T
W
W
L
S
Y
W
I
K
Q
G
S
G
N
T
T
V
T
R
G
N
E
T
S
V
S
D
-
S
M
K
D
N
P
H
M
Q
Y
Y
A
S
I
Y
A
L
S
M
A
V
M
L
I
L
928
ABCC6 939
L
R
A
V
G
-
P
C
L
Y
L
F
L
C
Q
Q
V
A
S
F
C
G
Y
W
L
S
L
A
D
D
P
A
-
-
-
-
-
-
-
-
-
-
-
-
V
G
G
Q
T
Q
-
-
-
-
A
A
L
R
G
G
I
F
L
L
G
C
L
Q
A
I
G
1001
ABCC8 1004
L
S
S
A
G
-
I
L
L
L
S
L
V
F
S
Q
L
L
K
M
V
L
V
A
I
D
Y
W
L
A
K
W
T
D
S
A
L
T
L
T
P
A
A
R
-
-
-
-
-
N
C
S
L
S
Q
E
C
T
L
D
T
V
Y
A
M
V
F
T
V
L
C
S
L
G
I
V
L
1077
ABCC9 986
L
T
S
G
G
-
F
F
L
L
I
L
M
I
F
S
K
L
L
K
H
S
V
I
V
A
I
D
Y
W
L
A
T
W
T
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
E
Y
S
I
N
N
T
G
K
A
D
Q
T
Y
Y
V
A
G
S
I
L
G
A
G
I
F
L
1049
ABCC10 919
S
Q
E
A
Q
-
P
S
T
S
P
A
S
M
G
L
F
S
P
Q
L
L
L
F
S
P
G
N
L
Y
I
P
V
F
P
L
P
K
A
-
-
-
-
-
-
-
-
-
-
-
-
A
P
N
G
S
S
D
-
-
-
-
I
R
F
Y
L
T
V
Y
A
T
I
A
G
V
N
S
L
C
981
ABCC11 797
I
Q
A
A
G
G
Y
M
V
S
C
I
I
F
F
F
V
V
L
I
V
F
L
T
I
F
S
F
W
W
L
S
Y
W
L
E
Q
G
S
G
T
S
S
R
E
S
G
T
M
A
D
L
G
N
I
A
D
N
P
Q
L
S
F
Y
Q
L
V
Y
G
L
N
A
L
L
L
I
C
V
876
ABCC12 786
I
K
A
G
G
Y
L
L
S
L
F
T
V
F
L
F
L
L
M
I
G
S
A
A
F
S
N
W
W
L
G
L
W
L
D
K
G
S
R
M
T
C
G
P
Q
G
N
R
T
M
C
E
V
G
A
V
L
A
D
I
G
Q
H
V
Y
Q
W
V
Y
T
A
S
M
V
F
M
L
V
F
865