Mutations at homologous positions to ABCC7 p.Ile618
Alignment: ABCC_full, Alignment of full length ABCC proteins, 2016-02-18 11:19:27Mutations exactly at the same position:
SNAP2 PROVEAN Effect_dbs |
||
---|---|---|
ABCC7 |
p.Ile618Thr
|
N
D
D
|
Mutations +/- 5 a.a. around the position:
ABCC7 |
p.Ala613Thr
p.Asp614Gly
p.Lys615Ala
p.Leu619Ser
p.His620Gln
p.His620Pro
p.Glu621Gly
p.Gly622Asp
p.Ser623Ala
|
D
N
D
D
?
D
D
?
D
D
D
D
D
D
N
D
?
D
D
D
N
N
?
|
ABCC1 |
p.Gly844Ser
|
D
D
?
|
ABCC4 |
p.Ala600Pro
|
D
D
?
|
ABCC6 |
p.Ala820Pro
p.Leu826Pro
p.Ala830Gly
|
D
D
D
D
D
D
N
N
?
|
ABCC8 |
p.Trp898Cys
p.Thr906Ala
|
N
D
?
N
N
?
|
ABCC9 |
p.Ser889Asn
|
N
N
?
|
The alignment around the queried position:
ABCC7 579
V
V
L
A
N
T
K
M
K
K
I
L
Y
F
Y
F
S
E
Q
N
P
D
F
S
K
L
M
G
C
S
Q
F
A
R
658
ABCC1 801
H
V
G
K
H
I
F
E
N
V
I
G
P
K
G
M
L
K
N
K
T
R
I
L
V
T
S
M
S
Y
L
P
V
D
V
I
I
V
M
S
G
K
I
S
E
G
S
Y
Q
E
L
L
A
R
D
G
F
A
E
F
L
R
T
Y
A
S
T
E
Q
E
Q
D
A
E
E
880
ABCC2 794
H
V
G
K
H
I
F
K
V
L
G
P
N
L
L
K
G
K
T
R
L
L
V
T
H
S
M
H
F
L
P
Q
V
D
E
I
V
V
L
G
N
G
T
I
V
E
K
G
S
Y
S
A
L
A
K
K
G
E
F
A
K
N
L
K
T
F
L
R
-
-
H
T
G
P
E
E
E
871
ABCC3 784
H
V
A
K
H
I
F
D
H
V
I
G
P
E
G
L
A
G
K
T
R
V
L
V
H
G
I
S
F
L
P
Q
T
D
F
I
I
V
L
A
D
G
Q
S
E
M
G
P
Y
P
A
L
L
Q
R
N
G
S
F
A
N
F
L
C
N
Y
A
P
D
E
D
Q
G
H
L
E
D
863
ABCC4 568
E
V
S
R
H
L
F
L
C
I
C
Q
I
-
-
L
H
E
K
I
I
L
V
T
H
Q
L
Q
Y
L
K
A
S
Q
I
L
I
L
K
D
G
K
M
V
Q
K
G
T
Y
T
E
F
L
K
S
G
D
F
G
S
L
L
K
K
D
N
E
E
S
E
Q
P
P
-
-
-
643
ABCC5 718
H
V
G
N
H
I
F
N
S
A
I
R
K
H
-
-
L
K
S
K
T
V
L
F
V
T
H
Q
L
Q
Y
L
V
D
C
D
E
V
I
F
M
K
E
G
C
I
T
E
R
G
T
H
E
E
L
M
N
L
N
G
D
Y
A
I
F
N
N
L
L
L
G
-
-
-
-
-
-
-
-
788
ABCC6 786
H
G
Q
H
V
F
Q
V
I
G
P
G
G
L
L
Q
G
T
T
I
L
H
A
L
H
I
L
P
Q
D
W
I
I
V
A
N
G
I
A
E
M
G
S
Y
Q
E
L
L
Q
R
K
G
A
L
C
L
D
Q
A
R
Q
P
G
D
R
G
E
G
E
T
865
ABCC8 862
H
L
S
D
H
L
M
Q
A
G
I
L
E
L
L
R
D
D
R
T
V
V
L
V
T
L
Q
Y
L
P
H
A
D
I
I
A
M
K
D
G
I
Q
R
E
G
T
L
K
D
F
R
S
E
C
Q
L
F
E
H
W
K
T
L
M
N
R
Q
D
Q
E
L
E
K
E
941
ABCC9 845
H
L
S
D
H
L
M
Q
E
G
I
L
K
F
L
Q
D
D
K
R
T
L
V
L
V
T
H
K
L
Q
Y
L
T
H
A
D
W
I
I
A
M
K
D
G
V
L
R
E
G
T
L
K
D
I
Q
T
K
D
V
E
L
Y
E
H
W
K
T
L
M
N
R
Q
D
Q
E
L
E
K
D
924
ABCC10 759
D
V
A
N
H
L
L
H
R
C
I
L
G
M
L
S
Y
T
T
R
-
-
L
L
C
T
H
R
T
E
Y
L
E
R
A
D
A
V
L
L
M
E
A
G
R
L
I
R
A
G
P
P
S
E
I
L
P
L
V
Q
A
V
P
K
A
W
A
E
N
G
Q
E
S
D
S
A
T
A
Q
S
836
ABCC11 667
H
V
G
K
H
I
F
E
E
C
I
K
K
T
-
-
L
R
G
K
T
V
V
L
V
T
H
Q
L
Q
Y
L
E
F
C
G
Q
I
I
L
L
E
N
G
K
I
C
E
N
G
T
H
S
E
L
M
Q
K
K
G
K
Y
A
Q
L
I
Q
K
M
H
-
-
-
-
-
-
-
-
-
-
735
ABCC12 636
H
V
G
K
H
V
F
E
E
C
I
K
K
T
-
-
L
R
G
K
T
V
V
L
V
T
H
Q
L
Q
F
L
E
S
C
D
E
V
I
L
L
E
D
G
E
I
C
E
K
G
T
H
K
E
L
M
E
E
R
G
R
Y
A
K
L
I
H
N
L
R
G
L
Q
F
K
D
P
E
H
L
713