Mutations at homologous positions to ABCC2 p.Gln1382
Alignment: ABCC_full, Alignment of full length ABCC proteins, 2016-02-18 11:19:27Mutations exactly at the same position:
|
SNAP2 PROVEAN Effect_dbs |
||
|---|---|---|
| ABCC2 |
p.Gln1382Arg
|
N
D
D
|
| ABCC1 |
p.Gln1375Met
p.Gln1375Leu
p.Gln1375Asn
|
D
D
?
D
D
?
D
D
?
|
| ABCC6 |
p.Gln1347His
|
N
D
D
|
| ABCC7 |
p.Gln1291His
p.Gln1291*
p.Gln1291Arg
p.Gln1291Ala
p.Gln1291Phe
p.Gln1291Tyr
p.Gln1291Trp
p.Gln1291Gly
|
N
D
D
-
-
N
D
D
D
?
D
D
?
D
D
?
D
D
?
D
D
?
|
| ABCC8 |
p.Gln1426Ala
|
D
D
?
|
Mutations +/- 5 a.a. around the position:
| ABCC2 |
p.Pro1381Thr
|
D
D
?
|
| ABCC4 |
p.Pro1121Ala
|
D
D
?
|
| ABCC6 |
p.Ile1342Thr
p.Pro1346Ser
p.Ile1350Leu
|
D
D
D
D
D
D
N
N
D
|
| ABCC7 |
p.Phe1286Ser
p.Phe1286Cys
p.Gly1287Arg
p.Pro1290Thr
p.Pro1290Ser
p.Lys1292Cys
p.Val1293Ile
p.Val1293Gly
p.Phe1294Cys
p.Phe1296Ser
p.Phe1296Ala
|
D
D
D
D
D
?
D
N
?
N
D
?
N
D
D
D
?
N
N
?
D
N
?
N
N
?
D
D
?
D
D
?
|
| ABCC8 |
p.Ile1424Val
|
N
N
?
|
The alignment around the queried position:
1734ABCC2 1343
L
T
N
C
L
F
R
L
A
A
G
G
Q
I
I
I
D
G
V
D
I
A
I
G
L
H
D
R
E
K
L
T
I
I
D
P
I
L
F
S
G
S
L
M
N
L
D
P
F
N
N
Y
S
D
E
E
I
W
K
A
L
E
L
A
L
K
S
F
V
A
S
L
1422
ABCC1 1336
L
L
G
L
F
R
I
N
E
S
E
G
E
I
I
I
D
G
I
N
I
A
K
I
L
L
F
K
I
T
I
I
P
D
P
V
L
F
S
S
L
R
M
N
L
D
P
F
S
Q
Y
S
D
E
E
V
W
S
L
E
L
A
H
L
K
D
F
V
S
A
L
1415
ABCC3 1332
M
T
L
C
L
F
R
I
L
E
A
A
K
G
E
I
I
D
G
L
N
V
A
D
I
G
L
H
R
S
L
T
I
I
P
Q
D
P
I
L
F
S
G
T
L
M
N
L
D
P
F
G
S
Y
S
E
E
D
I
W
W
L
E
L
S
H
L
H
F
V
S
S
Q
1411
ABCC4 1084
I
S
A
L
F
R
L
S
E
P
-
E
G
K
I
W
I
D
K
L
T
T
E
I
G
L
H
D
L
K
K
M
S
I
I
Q
E
P
V
L
F
T
G
M
R
K
N
L
D
P
F
N
E
H
D
E
E
L
W
N
A
L
Q
E
V
Q
L
K
E
T
I
E
D
L
1162
ABCC5 1236
L
G
M
L
F
R
L
V
E
L
S
G
C
K
I
D
G
V
R
I
S
D
I
G
L
A
D
L
R
S
K
L
S
I
I
P
Q
E
P
V
L
F
S
G
T
V
R
S
N
L
D
P
F
N
Q
Y
T
E
D
Q
I
W
D
A
L
E
R
T
H
M
K
E
C
I
A
Q
L
1315
ABCC6 1308
L
A
S
L
L
L
Q
E
A
A
E
G
I
I
V
P
A
H
V
G
H
T
L
S
R
S
I
I
D
P
L
F
P
S
L
M
N
L
L
L
Q
E
H
S
D
A
I
W
A
A
L
E
T
V
Q
L
K
A
L
V
A
S
L
1387
ABCC7 1253
L
A
R
N
-
E
G
E
I
I
G
V
S
W
D
S
I
T
L
A
V
I
I
S
G
F
R
L
P
E
K
A
D
G
S
Q
F
1331
ABCC8 1387
F
S
L
A
F
V
T
F
E
H
I
I
I
D
G
I
D
I
A
K
L
L
H
T
L
R
S
L
S
I
L
D
P
V
L
F
S
T
I
F
N
L
D
P
E
R
K
C
D
T
L
W
E
A
L
I
Q
L
K
L
V
V
K
A
L
1466
ABCC9 1355
L
S
L
A
F
F
R
M
V
D
I
F
D
G
K
I
V
I
D
G
I
D
I
S
K
L
P
L
H
T
L
R
S
R
L
S
I
I
L
Q
D
P
I
L
F
S
G
I
R
F
N
L
D
P
E
C
K
C
T
D
D
R
L
W
E
A
L
E
I
A
Q
L
K
N
M
V
K
S
L
1434
ABCC10 1289
L
L
L
V
L
F
R
L
L
E
P
S
S
G
R
V
L
L
D
G
V
D
T
S
Q
L
E
L
A
Q
L
R
S
Q
L
A
I
I
P
Q
E
P
F
L
F
S
G
T
V
R
E
N
L
D
P
Q
G
L
H
K
D
R
A
L
W
Q
A
L
K
Q
C
H
L
S
E
V
I
T
S
M
1368
ABCC11 1184
L
G
M
A
L
F
R
L
V
E
P
M
A
G
R
I
L
I
D
G
V
D
I
C
S
I
G
L
E
D
L
R
S
K
L
S
V
I
P
Q
D
P
V
L
L
S
G
T
I
R
F
N
L
D
P
F
D
R
H
T
D
Q
Q
I
W
D
A
L
E
R
T
F
L
T
K
A
I
S
K
F
1263
ABCC12 1163
L
G
M
A
L
F
R
L
V
E
P
A
S
G
T
I
F
I
D
E
V
D
I
C
I
L
S
L
E
D
L
R
T
K
L
T
V
I
P
Q
D
P
V
L
F
V
G
T
V
R
Y
N
L
D
P
F
E
S
H
T
E
M
L
W
Q
V
L
E
R
T
F
M
R
D
T
I
M
K
L
1242