Mutations at homologous positions to ABCB3 p.Arg273

Alignment: ABCB_halves, Alignment of ABC subunits from proteins in the ABCB subfamily, 2011-11-21 18:43:41

Mutations exactly at the same position:

Mutations +/- 5 a.a. around the position:

The alignment around the queried position:

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 493
ABCB3 236
Q
D
L
G
F
F
Q
-
-
E
T
K
T
G
E
L
N
S
R
L
S
S
D
T
T
L
M
S
N
W
L
P
L
N
A
N
V
L
L
R
S
L
V
K
V
V
G
L
Y
G
F
M
L
S
I
S
-
P
R
L
T
L
L
S
L
L
H
M
P
F
T
I
A
A
E
K
V
Y
N
T
 312
ABCB1 158
Q
E
I
G
W
F
D
-
-
V
H
D
V
G
E
L
N
T
R
L
T
D
D
V
S
K
I
N
E
G
I
G
D
K
I
G
M
F
F
Q
S
M
A
T
F
F
T
G
F
I
V
G
F
T
R
G
-
W
K
L
T
L
V
I
L
A
I
S
P
V
L
G
L
S
A
A
V
W
A
K
 234
ABCB1 799
Q
D
V
S
W
F
D
D
P
K
N
T
T
G
A
L
T
T
R
L
A
N
D
A
A
Q
V
K
G
A
I
G
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R
L
A
V
I
T
Q
N
I
A
N
L
G
T
G
I
I
I
S
F
I
Y
G
-
W
Q
L
T
L
L
L
L
A
I
V
P
I
I
A
I
A
G
V
V
E
M
K
 877
ABCB2 331
Q
E
T
E
F
F
Q
-
-
Q
N
Q
T
G
N
I
M
S
R
V
T
E
D
T
S
T
L
S
D
S
L
S
E
N
L
S
L
F
L
W
Y
L
V
R
G
L
C
L
L
G
I
M
L
W
G
S
-
V
S
L
T
M
V
T
L
I
T
L
P
L
L
F
L
L
P
K
K
V
G
K
 407
ABCB4 160
Q
E
I
G
W
F
D
-
-
I
N
D
T
T
E
L
N
T
R
L
T
D
D
I
S
K
I
S
E
G
I
G
D
K
V
G
M
F
F
Q
A
V
A
T
F
F
A
G
F
I
V
G
F
I
R
G
-
W
K
L
T
L
V
I
M
A
I
S
P
I
L
G
L
S
A
A
V
W
A
K
 236
ABCB4 798
Q
D
M
S
W
F
D
D
H
K
N
S
T
G
A
L
S
T
R
L
A
T
D
A
A
Q
V
Q
G
A
T
G
T
R
L
A
L
I
A
Q
N
I
A
N
L
G
T
G
I
I
I
S
F
I
Y
G
-
W
Q
L
T
L
L
L
L
A
V
V
P
I
I
A
V
S
G
I
V
E
M
K
 876
ABCB5 334
Q
D
I
A
W
F
D
E
K
E
N
S
T
G
G
L
T
T
I
L
A
I
D
I
A
Q
I
Q
G
A
T
G
S
R
I
G
V
L
T
Q
N
A
T
N
M
G
L
S
V
I
I
S
F
I
Y
G
-
W
E
M
T
F
L
I
L
S
I
A
P
V
L
A
V
T
G
M
I
E
T
A
 412
ABCB6 356
L
S
L
R
W
H
L
G
-
-
R
R
T
G
E
V
L
R
I
A
D
R
G
T
S
S
V
T
G
L
L
S
Y
L
V
F
N
V
I
P
T
L
A
D
I
I
I
G
I
I
Y
F
S
M
F
F
N
A
W
F
G
L
I
V
F
L
C
M
S
L
Y
L
T
L
T
I
V
V
T
E
 433
ABCB7 236
L
D
L
G
F
H
L
S
-
-
R
Q
T
G
A
L
S
K
A
I
D
R
G
T
R
G
I
S
F
V
L
S
A
L
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F
N
L
L
P
I
M
F
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M
L
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G
V
L
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K
C
G
A
Q
F
A
L
V
T
L
G
T
L
G
T
Y
T
A
F
T
V
A
V
T
R
 313
ABCB8 238
Q
D
I
T
F
F
D
-
-
A
N
K
T
G
Q
L
V
S
R
L
T
T
D
V
Q
E
F
K
S
S
F
K
L
V
I
S
Q
G
L
R
S
C
T
Q
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A
G
C
L
V
S
L
S
M
L
S
-
T
R
L
T
L
L
L
M
V
A
T
P
A
L
M
G
V
G
T
L
M
G
S
 314
ABCB9 272
Q
E
T
S
F
F
D
-
-
E
N
R
T
G
D
L
I
S
R
L
T
S
D
T
T
M
V
S
D
L
V
S
Q
N
I
N
V
F
L
R
N
T
V
K
V
T
G
V
V
V
F
M
F
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L
S
-
W
Q
L
S
L
V
T
F
M
G
F
P
I
I
M
M
V
S
N
I
Y
G
K
 348
ABCB10 258
Q
E
V
A
F
F
D
-
-
K
T
R
T
G
E
L
I
N
R
L
S
S
D
T
A
L
L
G
R
S
V
T
E
N
L
S
D
G
L
R
A
G
A
Q
A
S
V
G
I
S
M
M
F
F
V
S
-
P
N
L
A
T
F
V
L
S
V
V
P
P
V
S
I
I
A
V
I
Y
G
R
 334
ABCB11 185
M
E
I
G
W
F
D
-
-
C
N
S
V
G
E
L
N
T
R
F
S
D
D
I
N
K
I
N
D
A
I
A
D
Q
M
A
L
F
I
Q
R
M
T
S
T
I
C
G
F
L
L
G
F
F
R
G
-
W
K
L
T
L
V
I
I
S
V
S
P
L
I
G
I
G
A
A
T
I
G
L
 261
ABCB11 842
Q
D
I
A
W
F
D
D
L
R
N
S
P
G
A
L
T
T
R
L
A
T
D
A
S
Q
V
Q
G
A
A
G
S
Q
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G
M
I
V
N
S
F
T
N
V
T
V
A
M
I
I
A
F
S
F
S
-
W
K
L
S
L
V
I
L
C
F
F
P
F
L
A
L
S
G
A
T
Q
T
R
 920