ABCB1 p.Ile190Cys

Predicted by SNAP2: A: N (61%), C: N (66%), D: D (85%), E: D (85%), F: N (82%), G: D (80%), H: D (80%), K: D (80%), L: N (82%), M: N (93%), N: D (80%), P: D (85%), Q: D (75%), R: D (85%), S: D (71%), T: D (66%), V: N (97%), W: D (80%), Y: D (75%),
Predicted by PROVEAN: A: N, C: D, D: D, E: D, F: D, G: D, H: D, K: D, L: N, M: N, N: D, P: D, Q: D, R: D, S: D, T: D, V: N, W: D, Y: D,

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[hide] Loo TW, Clarke DM
The packing of the transmembrane segments of human multidrug resistance P-glycoprotein is revealed by disulfide cross-linking analysis.
J Biol Chem. 2000 Feb 25;275(8):5253-6., 2000-02-25 [PMID:10681495] [PubMed]

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[hide] Loo TW, Bartlett MC, Clarke DM
Suppressor mutations in the transmembrane segments of P-glycoprotein promote maturation of processing mutants and disrupt a subset of drug-binding sites.
J Biol Chem. 2007 Nov 2;282(44):32043-52. Epub 2007 Sep 11., 2007-11-02 [PMID:17848563] [PubMed]

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