Mutations at homologous positions to ABCA1 p.Thr2073
Alignment: ABCA_full, Alignment of full length ABCA proteins, 2016-02-18 11:17:15Mutations exactly at the same position:
|
SNAP2 PROVEAN Effect_dbs |
||
|---|---|---|
| ABCA1 |
p.Thr2073Ala
p.Thr2073Asn
|
N
D
?
D
D
?
|
Mutations +/- 5 a.a. around the position:
| ABCA1 |
p.Gly2074Asn
p.Gly2074Gln
p.Asp2076Ala
p.Pro2077His
|
D
D
?
D
D
?
D
D
?
D
D
?
|
| ABCA4 |
p.Asp2095Val
p.Glu2096Lys
p.Asp2102Glu
|
D
D
?
D
D
N
D
?
|
| ABCA7 |
p.Pro1952Arg
|
N
D
?
|
The alignment around the queried position:
5269ABCA1 2034
L
V
K
Y
G
E
K
A
G
N
G
G
N
K
R
K
L
T
A
M
A
L
I
G
G
P
P
V
V
F
L
D
E
P
T
M
K
A
R
F
L
W
N
C
A
L
S
V
K
E
-
G
R
S
V
V
L
T
S
H
S
M
E
E
C
E
L
C
T
2112
ABCA2 2175
L
T
K
Y
A
D
K
P
A
G
T
Y
S
G
G
N
K
R
K
L
S
T
A
I
A
L
I
G
Y
P
A
F
I
F
L
D
E
P
T
T
G
M
D
P
K
A
R
R
F
L
W
N
L
I
L
D
L
I
K
T
-
G
R
S
V
V
L
T
S
H
S
M
E
E
C
E
A
L
C
T
2253
ABCA3 1504
L
E
P
H
A
N
K
L
V
R
T
G
G
N
K
K
L
S
T
G
I
A
L
I
G
E
P
A
V
I
F
L
D
E
P
S
T
G
M
D
P
V
A
R
W
D
T
V
A
R
A
E
S
-
G
K
A
I
I
I
T
S
H
S
M
E
E
C
A
C
T
1582
ABCA4 2060
T
V
Y
A
D
C
L
A
G
G
N
K
K
L
S
T
A
I
A
L
I
G
C
P
P
L
V
L
L
P
T
T
G
M
P
Q
A
M
L
N
V
V
S
I
I
-
G
R
A
V
V
L
T
S
C
E
A
L
T
2138
ABCA5 1423
K
E
H
L
Q
K
T
V
K
K
L
P
A
G
I
K
R
K
L
C
F
A
L
S
M
L
G
N
P
Q
I
T
L
L
D
E
P
S
T
G
M
D
P
K
A
K
Q
H
M
W
R
A
I
R
T
A
F
K
N
R
K
R
A
A
I
L
T
T
H
Y
M
E
E
A
E
A
V
C
D
R
1502
ABCA6 1403
H
E
Q
L
N
V
P
V
Q
K
L
T
A
G
I
T
R
K
L
C
F
V
L
S
L
L
G
N
S
P
V
L
L
L
D
E
P
S
T
G
I
D
P
T
G
Q
Q
Q
M
W
Q
A
I
Q
A
V
V
K
N
T
E
R
G
V
L
L
T
T
H
N
L
A
E
A
E
A
L
C
D
R
1482
ABCA7 1915
L
S
W
Y
A
D
R
P
A
G
T
Y
S
G
G
N
K
R
K
L
A
T
A
L
A
L
V
G
D
P
A
V
V
F
L
D
E
T
T
G
M
D
P
S
A
R
R
F
L
W
N
S
L
L
A
V
V
R
E
-
G
R
S
V
M
L
T
S
H
S
M
E
E
C
E
A
L
C
S
1993
ABCA8 1368
Q
D
Q
L
K
S
P
V
K
T
L
S
E
G
I
K
R
K
L
C
F
V
L
S
I
L
G
N
P
S
V
V
L
L
D
E
P
S
T
G
M
D
P
E
G
Q
Q
Q
M
W
Q
A
I
R
A
T
F
R
N
T
E
R
G
A
L
L
T
T
H
Y
M
A
E
A
E
A
V
C
D
R
1447
ABCA9 1411
Q
D
Q
L
K
A
P
V
K
T
L
S
E
G
I
K
R
K
L
C
F
V
L
S
I
L
G
N
P
S
V
V
L
L
D
E
P
S
T
G
M
D
P
E
G
Q
Q
Q
M
W
Q
V
I
R
A
T
F
R
N
T
E
R
G
A
L
L
T
T
H
Y
M
A
E
A
E
A
V
C
D
R
1490
ABCA10 1330
Q
E
Q
L
K
A
P
V
K
T
L
S
E
G
I
K
R
K
L
C
F
V
L
S
I
L
G
N
P
S
V
V
L
L
D
E
P
F
T
G
M
D
P
E
G
Q
Q
Q
M
W
Q
I
L
Q
A
T
V
K
N
K
E
R
G
T
L
L
T
T
H
Y
M
S
E
A
E
A
V
C
D
R
1409
ABCA12 2379
L
M
P
F
K
D
R
A
T
S
M
C
S
Y
G
T
K
R
K
L
S
T
A
L
A
L
I
G
K
P
S
I
L
L
L
D
E
P
S
S
G
M
D
P
K
S
K
R
H
L
W
K
I
I
S
E
E
V
Q
N
-
K
C
S
V
I
L
T
S
H
S
M
E
E
C
E
A
L
C
T
2457
ABCA13 4846
L
E
A
H
A
D
K
P
V
A
T
Y
S
G
G
T
K
R
K
L
S
T
A
L
A
L
V
G
K
P
D
I
L
L
L
D
E
P
S
S
G
M
D
P
C
S
K
R
Y
L
W
Q
T
I
M
K
E
V
R
E
-
G
C
A
A
V
L
T
S
H
S
M
E
E
C
E
A
L
C
T
4924