Mutations at homologous positions to ABCC7 p.Asn1303
Alignment: ABCC_full, Alignment of full length ABCC proteins, 2016-02-18 11:19:27Mutations exactly at the same position:
|
SNAP2 PROVEAN Effect_dbs |
||
|---|---|---|
| ABCC7 |
p.Asn1303Lys
p.Asn1303His
p.Asn1303Ile
p.Asn1303Ala
p.Asn1303Gln
p.Asn1303Leu
p.Asn1303Arg
p.Asn1303Phe
|
D
D
D
N
D
D
D
D
D
D
D
D
D
D
D
D
D
D
D
D
D
D
D
|
Mutations +/- 5 a.a. around the position:
| ABCC7 |
p.Thr1299Ile
p.Lys1302Gln
p.Asp1305Glu
p.Tyr1307Cys
p.Tyr1307Asn
p.Tyr1307*
p.Glu1308*
p.Glu1308Ala
|
D
D
N
N
?
D
D
N
D
N
N
?
-
-
-
-
N
N
?
|
| ABCC1 |
p.Gly1382Ser
|
D
D
?
|
| ABCC2 |
p.Arg1392His
p.Arg1392Met
|
D
D
?
D
D
?
|
| ABCC3 |
p.Arg1381Ser
|
D
D
?
|
| ABCC4 |
p.Thr1130Met
|
D
D
?
|
| ABCC6 |
p.Gly1354Arg
p.Arg1357Trp
p.Asp1361Asn
|
D
D
D
D
D
D
N
D
D
|
| ABCC8 |
p.Gly1433Asp
p.Arg1436Gln
p.Arg1436Cys
|
D
D
?
D
D
?
D
D
?
|
| ABCC9 |
p.Ser1402Cys
|
D
D
?
|
The alignment around the queried position:
1746ABCC7 1264
E
G
E
I
I
G
V
S
W
D
S
I
T
L
A
V
I
I
S
G
F
R
L
P
E
K
A
D
G
S
Q
F
P
G
K
V
G
G
1343
ABCC1 1348
E
G
E
I
I
I
D
G
I
N
I
A
K
I
L
L
F
K
I
T
I
I
P
D
P
V
L
F
S
S
L
R
M
N
L
D
P
F
S
Q
Y
S
D
E
E
V
W
S
L
E
L
A
H
L
K
D
F
V
S
A
L
P
D
K
L
D
H
E
A
E
G
G
1427
ABCC2 1355
G
G
Q
I
I
I
D
G
V
D
I
A
I
G
L
H
D
R
E
K
L
T
I
I
D
P
I
L
F
S
G
S
L
M
N
L
D
P
F
N
N
Y
S
D
E
E
I
W
K
A
L
E
L
A
L
K
S
F
V
A
S
L
Q
L
G
L
S
H
E
V
T
E
A
G
1434
ABCC3 1344
K
G
E
I
I
D
G
L
N
V
A
D
I
G
L
H
R
S
L
T
I
I
P
Q
D
P
I
L
F
S
G
T
L
M
N
L
D
P
F
G
S
Y
S
E
E
D
I
W
W
L
E
L
S
H
L
H
F
V
S
S
Q
P
A
G
L
D
F
Q
C
S
E
G
1423
ABCC4 1095
E
G
K
I
W
I
D
K
L
T
T
E
I
G
L
H
D
L
K
K
M
S
I
I
Q
E
P
V
L
F
T
G
M
R
K
N
L
D
P
F
N
E
H
D
E
E
L
W
N
A
L
Q
E
V
Q
L
K
E
T
I
E
D
L
P
G
K
M
D
T
E
L
A
E
G
1174
ABCC5 1248
G
C
K
I
D
G
V
R
I
S
D
I
G
L
A
D
L
R
S
K
L
S
I
I
P
Q
E
P
V
L
F
S
G
T
V
R
S
N
L
D
P
F
N
Q
Y
T
E
D
Q
I
W
D
A
L
E
R
T
H
M
K
E
C
I
A
Q
L
P
L
K
L
E
S
E
V
M
E
N
G
1327
ABCC6 1320
E
G
I
I
V
P
A
H
V
G
H
T
L
S
R
S
I
I
D
P
L
F
P
S
L
M
N
L
L
L
Q
E
H
S
D
A
I
W
A
A
L
E
T
V
Q
L
K
A
L
V
A
S
L
P
G
Q
L
Q
Y
C
A
D
G
1399
ABCC8 1399
E
H
I
I
I
D
G
I
D
I
A
K
L
L
H
T
L
R
S
L
S
I
L
D
P
V
L
F
S
T
I
F
N
L
D
P
E
R
K
C
D
T
L
W
E
A
L
I
Q
L
K
L
V
V
K
A
L
P
G
L
A
I
I
T
E
1478
ABCC9 1367
D
G
K
I
V
I
D
G
I
D
I
S
K
L
P
L
H
T
L
R
S
R
L
S
I
I
L
Q
D
P
I
L
F
S
G
I
R
F
N
L
D
P
E
C
K
C
T
D
D
R
L
W
E
A
L
E
I
A
Q
L
K
N
M
V
K
S
L
P
G
G
L
D
A
V
V
T
E
G
G
1446
ABCC10 1301
S
G
R
V
L
L
D
G
V
D
T
S
Q
L
E
L
A
Q
L
R
S
Q
L
A
I
I
P
Q
E
P
F
L
F
S
G
T
V
R
E
N
L
D
P
Q
G
L
H
K
D
R
A
L
W
Q
A
L
K
Q
C
H
L
S
E
V
I
T
S
M
G
G
-
L
D
G
E
L
G
E
G
G
1379
ABCC11 1196
A
G
R
I
L
I
D
G
V
D
I
C
S
I
G
L
E
D
L
R
S
K
L
S
V
I
P
Q
D
P
V
L
L
S
G
T
I
R
F
N
L
D
P
F
D
R
H
T
D
Q
Q
I
W
D
A
L
E
R
T
F
L
T
K
A
I
S
K
F
P
K
K
L
H
T
D
V
V
E
N
G
1275
ABCC12 1175
S
G
T
I
F
I
D
E
V
D
I
C
I
L
S
L
E
D
L
R
T
K
L
T
V
I
P
Q
D
P
V
L
F
V
G
T
V
R
Y
N
L
D
P
F
E
S
H
T
E
M
L
W
Q
V
L
E
R
T
F
M
R
D
T
I
M
K
L
P
E
K
L
Q
A
E
V
T
E
N
G
1254