Mutations at homologous positions to ABCA4 p.Trp782
Alignment: ABCA_full, Alignment of full length ABCA proteins, 2016-02-18 11:17:15Mutations exactly at the same position:
SNAP2 PROVEAN Effect_dbs |
||
---|---|---|
ABCA4 |
p.Trp782*
|
-
-
?
|
Mutations +/- 5 a.a. around the position:
ABCA1 |
p.Val771Met
|
N
N
?
|
ABCA10 |
p.Pro265Phe
|
D
D
?
|
ABCA13 |
p.Ser3704Arg
|
D
!
?
|
The alignment around the queried position:
ABCA4 747
L
F
L
L
S
T
F
F
S
K
A
S
L
A
A
I
Y
F
T
L
Y
L
P
H
I
L
C
F
A
-
-
-
-
Q
D
R
M
T
A
E
L
K
K
A
V
L
S
P
V
F
G
F
G
T
E
L
V
R
F
E
E
Q
G
L
L
Q
S
822
ABCA1 732
Q
F
L
I
S
T
L
F
S
R
A
N
L
A
A
A
C
G
G
I
I
Y
F
T
L
Y
L
P
Y
V
L
C
V
A
-
-
-
-
W
Q
D
Y
G
F
L
I
F
A
S
L
L
S
P
V
A
F
F
G
E
F
A
L
F
E
E
Q
G
I
G
V
Q
W
D
807
ABCA2 799
F
C
F
L
V
S
V
L
Y
S
K
A
K
L
A
S
A
C
G
G
I
I
Y
F
L
S
Y
V
P
Y
M
Y
V
A
I
R
E
E
V
A
H
D
K
I
T
A
F
E
K
C
I
A
S
L
M
S
T
T
A
F
G
L
G
S
K
Y
F
A
L
Y
E
V
A
G
V
G
I
Q
W
H
878
ABCA3 360
F
S
F
M
V
S
T
F
F
S
K
A
N
M
A
A
A
F
G
F
L
Y
F
F
T
Y
I
Y
F
F
V
A
P
-
-
-
-
R
Y
N
W
M
T
L
S
Q
K
L
C
S
C
L
L
S
N
V
A
M
A
M
G
A
Q
L
I
G
K
F
E
A
K
G
M
G
I
Q
W
R
435
ABCA5 314
A
L
M
L
T
P
L
F
K
K
S
-
-
-
-
K
H
V
G
I
V
E
F
F
V
T
V
A
F
G
F
I
G
L
-
M
I
I
L
I
E
S
F
P
K
S
L
V
W
L
F
S
P
F
C
H
C
T
F
V
I
G
I
A
Q
V
M
H
L
E
D
F
N
E
G
A
S
F
S
N
388
ABCA6 315
V
F
L
M
S
V
L
L
K
K
A
-
-
-
-
V
L
T
N
L
V
V
F
L
L
T
L
F
W
G
C
L
G
-
-
F
T
V
F
Y
E
Q
L
P
S
S
L
E
W
I
L
N
I
C
S
P
F
A
F
T
T
G
M
I
Q
I
I
K
L
D
Y
N
L
N
G
V
I
F
P
D
388
ABCA7 642
Q
S
F
L
L
S
A
F
F
S
R
A
N
L
A
A
A
C
G
G
L
A
Y
F
S
L
Y
L
P
Y
V
L
C
V
A
-
-
-
-
W
R
D
R
L
P
A
G
G
R
V
A
A
S
L
L
S
P
V
A
F
G
F
G
C
E
S
L
A
L
L
E
E
Q
G
E
G
A
Q
W
H
717
ABCA8 317
A
F
L
M
S
I
L
V
K
K
S
-
-
-
-
F
L
T
G
L
V
V
F
L
L
T
V
F
W
G
C
L
G
-
-
F
T
S
L
Y
R
H
L
P
A
S
L
E
W
I
L
S
L
L
S
P
F
A
F
M
L
G
M
A
Q
L
L
H
L
D
Y
D
L
N
S
N
A
F
P
H
390
ABCA9 318
A
F
L
M
S
V
L
I
K
K
P
-
-
-
-
F
L
T
G
L
V
V
F
L
L
I
V
F
W
G
I
L
G
-
-
F
P
A
L
Y
T
R
L
P
A
F
L
E
W
T
L
C
L
L
S
P
F
A
F
T
V
G
M
A
Q
L
I
H
L
D
Y
D
V
N
S
N
A
H
L
D
391
ABCA10 228
A
F
L
M
S
V
L
I
R
K
P
-
-
-
-
M
L
A
G
L
A
G
F
L
F
T
V
F
W
G
C
L
G
-
-
F
T
V
L
Y
R
Q
L
L
S
L
G
W
V
L
S
L
L
S
P
F
A
F
T
A
G
M
A
Q
I
T
H
L
D
N
Y
L
S
G
V
I
F
P
D
301
ABCA12 1161
M
S
Y
L
I
S
V
F
F
N
N
T
N
I
A
A
L
I
S
L
I
Y
I
I
A
F
F
P
F
I
V
L
V
T
-
-
-
-
V
E
N
E
L
S
Y
V
L
K
V
F
M
S
L
L
S
P
T
A
F
S
Y
A
S
Q
Y
I
A
Y
E
E
Q
G
I
G
L
Q
E
1236
ABCA13 3664
L
S
Y
L
L
S
A
F
F
S
Q
A
N
T
A
A
L
C
T
S
L
V
Y
M
I
S
F
L
P
Y
I
V
L
L
V
-
-
-
-
L
H
N
Q
L
F
V
N
Q
T
F
L
C
L
L
S
T
T
A
F
G
Q
G
V
F
F
I
T
F
L
E
G
Q
E
T
G
I
Q
W
N
3739