Mutations in ABCD3
reference sequence
Region |
Mutation |
|
|
Publications |
Sentences |
MutMiner_hits |
SNAP2 |
PROVEAN |
Effect_ExpVar |
TMD1,TH1 |
p.Asn
12
Phe
|
details |
homologous mutations |
1 |
7 |
8 |
D |
N |
? |
TMD1,TH1 |
p.Gly
17
Asp
|
details |
homologous mutations |
1 |
1 |
1 |
D |
N |
|
TMD1,TH1 |
p.Ala
18
Val
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
TMD1,TH1 |
p.Ala
19
Val
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
TMD1,TH1 |
p.Phe
20
Val
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
TMD1,TH1 |
p.Leu
21
Gln
|
details |
homologous mutations |
1 |
27 |
50 |
N |
N |
? |
TMD1,TH1 |
p.Leu
21
Ala
|
details |
homologous mutations |
1 |
10 |
10 |
N |
N |
? |
TMD1,TH1 |
p.Leu
22
Gln
|
details |
homologous mutations |
1 |
29 |
53 |
N |
N |
? |
TMD1,TH1 |
p.Leu
22
Ala
|
details |
homologous mutations |
1 |
10 |
10 |
N |
N |
? |
TMD1,TH1 |
p.Leu
23
Ala
|
details |
homologous mutations |
1 |
10 |
10 |
N |
N |
? |
TMD1,TH1 |
p.Leu
23
Gln
|
details |
homologous mutations |
1 |
28 |
51 |
N |
N |
? |
TMD1,EL1 |
p.Lys
28
Ala
|
details |
homologous mutations |
1 |
6 |
6 |
N |
N |
? |
TMD1,EL1 |
p.Arg
29
Ala
|
details |
homologous mutations |
1 |
6 |
6 |
N |
N |
? |
TMD1,EL1 |
p.Arg
30
Ala
|
details |
homologous mutations |
1 |
6 |
6 |
N |
N |
? |
TMD1,EL1 |
p.Arg
31
Ala
|
details |
homologous mutations |
1 |
6 |
6 |
N |
N |
? |
TMD1,EL1 |
p.Lys
38
Ala
|
details |
homologous mutations |
1 |
6 |
6 |
N |
N |
? |
TMD1,EL1 |
p.Lys
39
Ala
|
details |
homologous mutations |
1 |
6 |
6 |
N |
N |
? |
TMD1,EL1 |
p.Lys
53
Ala
|
details |
homologous mutations |
1 |
4 |
4 |
N |
D |
? |
TMD1,EL1 |
p.Lys
54
Ala
|
details |
homologous mutations |
1 |
6 |
6 |
N |
N |
? |
TMD1,EL1 |
p.Glu
55
Lys
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
TMD1,EL1 |
p.Arg
56
Ala
|
details |
homologous mutations |
1 |
6 |
6 |
D |
D |
? |
TMD1,TH2 |
p.Lys
61
Ala
|
details |
homologous mutations |
1 |
6 |
6 |
N |
N |
? |
TMD1,TH2 |
p.Val
62
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
TMD1,TH2 |
p.Phe
63
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,TH2 |
p.Phe
64
Leu
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
TMD1,TH2 |
p.Ser
65
Thr
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
TMD1,TH2 |
p.Arg
66
Ala
|
details |
homologous mutations |
1 |
6 |
6 |
D |
D |
? |
TMD1,TH2 |
p.Leu
67
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,TH2 |
p.Ile
68
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
TMD1,TH2 |
p.Ile
70
Asn
|
details |
homologous mutations |
1 |
28 |
48 |
D |
D |
? |
TMD1,TH2 |
p.Ile
70
Ala
|
details |
homologous mutations |
1 |
8 |
9 |
N |
D |
? |
TMD1,TH2 |
p.Leu
71
Gln
|
details |
homologous mutations |
1 |
31 |
52 |
D |
D |
? |
TMD1,TH2 |
p.Leu
71
Ala
|
details |
homologous mutations |
1 |
10 |
12 |
N |
D |
? |
TMD1,TH2 |
p.Lys
72
Ala
|
details |
homologous mutations |
1 |
6 |
6 |
D |
D |
? |
TMD1,CL1 |
p.Pro
76
Ala
|
details |
homologous mutations |
1 |
4 |
4 |
D |
D |
? |
TMD1,CL1 |
p.Arg
77
Ala
|
details |
homologous mutations |
1 |
6 |
6 |
D |
N |
? |
TMD1,CL1 |
p.Glu
82
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,CL1 |
p.Thr
83
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
TMD1,CL1 |
p.Gly
84
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
N |
D |
? |
TMD1,CL1 |
p.Tyr
85
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,TH3 |
p.Leu
86
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
N |
D |
? |
TMD1,TH3 |
p.Leu
88
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
N |
D |
? |
TMD1,TH3 |
p.Ser
95
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
TMD1,TH3 |
p.Arg
96
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,EL2 |
p.Gly
113
Val
|
details |
homologous mutations |
1 |
2 |
2 |
D |
N |
? |
TMD1,EL2 |
p.Ile
114
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,EL2 |
p.Gly
116
Arg
|
details |
homologous mutations |
3 |
11 |
11 |
N |
N |
? |
TMD1,EL2 |
p.Arg
117
Ala
|
details |
homologous mutations |
1 |
6 |
6 |
N |
D |
? |
TMD1,EL2 |
p.Arg
119
Ala
|
details |
homologous mutations |
1 |
6 |
6 |
N |
N |
? |
TMD1,EL2 |
p.Lys
120
Ala
|
details |
homologous mutations |
1 |
6 |
6 |
N |
N |
? |
TMD1,EL2 |
p.Lys
123
Ala
|
details |
homologous mutations |
1 |
6 |
6 |
N |
D |
? |
TMD1,EL2 |
p.Arg
124
Ala
|
details |
homologous mutations |
1 |
6 |
6 |
N |
N |
? |
TMD1,CL2 |
p.Asn
148
Ser
|
details |
homologous mutations |
3 |
5 |
5 |
N |
N |
? |
TMD1,CL2 |
p.Leu
207
Pro
|
details |
homologous mutations |
1 |
3 |
3 |
D |
D |
? |
TMD1,CL2 |
p.Gly
226
Arg
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,CL2 |
p.Glu
277
Asp
|
details |
homologous mutations |
1 |
6 |
6 |
D |
D |
? |
TMD1,CL2 |
p.Glu
278
Asp
|
details |
homologous mutations |
1 |
6 |
6 |
D |
D |
? |
TMD1,CL2 |
p.Ile
307
Asn
|
details |
homologous mutations |
1 |
23 |
34 |
D |
D |
? |
TMD1,CL2 |
p.Ile
307
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
N |
D |
? |
TMD1,CL2 |
p.Leu
308
Gln
|
details |
homologous mutations |
1 |
23 |
36 |
N |
N |
? |
TMD1,CL2 |
p.Leu
308
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
CL3,NBD1 |
p.Arg
464
*
|
details |
homologous mutations |
1 |
1 |
1 |
- |
- |
? |
CL3,NBD1,WA1 |
p.Gly
478
Arg
|
details |
homologous mutations |
2 |
12 |
13 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Lys
479
Ala
|
details |
homologous mutations |
1 |
3 |
3 |
D |
D |
? |
CL3,NBD1 |
p.Leu
516
Pro
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1,SIG1 |
p.Ser
572
Ile
|
details |
homologous mutations |
2 |
12 |
13 |
D |
D |
? |
CL3,NBD1 |
p.Gln
590
*
|
details |
homologous mutations |
1 |
1 |
1 |
- |
- |
? |
CL3,NBD1 |
p.Glu
606
Lys
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |