Mutations in ABCB3
reference sequence
Region |
Mutation |
|
|
Publications |
Sentences |
MutMiner_hits |
SNAP2 |
PROVEAN |
Effect_ExpVar |
ELa |
p.Leu
3
Val
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
TMD0,THa |
p.Gly
25
Ala
|
details |
homologous mutations |
1 |
7 |
7 |
D |
N |
? |
TMD0,CLa |
p.Leu
46
Pro
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD0,THb |
p.Cys
70
Ser
|
details |
homologous mutations |
1 |
2 |
2 |
N |
D |
? |
TMD0,THb |
p.Leu
75
*
|
details |
homologous mutations |
1 |
3 |
3 |
- |
- |
? |
CL0 |
p.Ser
145
Ala
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
TMD1,TH1 |
p.Glu
166
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,EL1 |
p.Arg
175
His
|
details |
homologous mutations |
2 |
8 |
8 |
N |
D |
? |
TMD1,EL1 |
p.Asp
178
Lys
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,EL1 |
p.Asp
178
Arg
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,EL1 |
p.Leu
180
Gln
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,EL1 |
p.Leu
180
Pro
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,EL1 |
p.Gly
181
Arg
|
details |
homologous mutations |
1 |
11 |
11 |
N |
D |
? |
TMD1,EL1 |
p.Ala
192
Thr
|
details |
homologous mutations |
1 |
10 |
10 |
N |
D |
? |
TMD1,TH2 |
p.Cys
197
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
N |
D |
? |
TMD1,TH2 |
p.Cys
209
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
N |
D |
? |
TMD1,TH2 |
p.Cys
213
Met
|
details |
homologous mutations |
1 |
3 |
3 |
N |
N |
? |
TMD1,TH2 |
p.Cys
213
Ser
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
TMD1,CL1 |
p.Ser
251
Pro
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,CL1 |
p.Ser
251
Cys
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,CL1 |
p.Ser
251
Ala
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,CL1 |
p.Thr
257
Ile
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,TH3 |
p.Pro
265
Phe
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,TH3 |
p.Leu
266
Phe
|
details |
homologous mutations |
1 |
5 |
5 |
N |
N |
? |
TMD1,TH3 |
p.Leu
272
Pro
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,TH3 |
p.Arg
273
His
|
details |
homologous mutations |
1 |
3 |
3 |
D |
D |
? |
TMD1,TH3 |
p.Met
285
Cys
|
details |
homologous mutations |
1 |
2 |
4 |
N |
D |
? |
TMD1,TH4 |
p.Thr
293
Pro
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,TH4 |
p.Arg
313
His
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
TMD1,CL2 |
p.Val
331
Cys
|
details |
homologous mutations |
1 |
4 |
4 |
N |
D |
? |
TMD1,CL2 |
p.Gly
338
Ala
|
details |
homologous mutations |
1 |
1 |
2 |
N |
N |
? |
TMD1,CL2 |
p.Cys
353
Ser
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
TMD1,CL2 |
p.Cys
362
Ala
|
details |
homologous mutations |
1 |
5 |
5 |
N |
N |
? |
TMD1,TH5 |
p.Arg
373
Cys
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
TMD1,TH5 |
p.Ala
374
Asp
|
details |
homologous mutations |
4 |
9 |
9 |
D |
D |
? |
TMD1,TH5 |
p.Ala
374
Thr
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,TH5 |
p.Val
379
Ile
|
details |
homologous mutations |
13 |
22 |
23 |
N |
N |
N |
TMD1,TH5 |
p.Val
379
Ala
|
details |
homologous mutations |
1 |
1 |
2 |
N |
N |
? |
TMD1,TH5 |
p.Arg
380
Gln
|
details |
homologous mutations |
1 |
1 |
1 |
D |
N |
? |
TMD1,EL3 |
p.Cys
394
Val
|
details |
homologous mutations |
1 |
2 |
2 |
N |
D |
? |
TMD1,EL3 |
p.Leu
410
Phe
|
details |
homologous mutations |
4 |
15 |
16 |
N |
D |
? |
CL3 |
p.Leu
464
Phe
|
details |
homologous mutations |
1 |
1 |
1 |
N |
D |
? |
CL3,NBD1,WA1 |
p.Lys
509
Met
|
details |
homologous mutations |
3 |
93 |
119 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Lys
509
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
CL3,NBD1 |
p.Cys
540
His
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
CL3,NBD1 |
p.Glu
552
Gln
|
details |
homologous mutations |
4 |
41 |
44 |
D |
D |
? |
CL3,NBD1 |
p.Glu
552
Ala
|
details |
homologous mutations |
2 |
2 |
2 |
D |
D |
? |
CL3,NBD1 |
p.Ala
565
Thr
|
details |
homologous mutations |
13 |
21 |
22 |
N |
N |
? |
CL3,NBD1 |
p.Cys
571
Ser
|
details |
homologous mutations |
1 |
2 |
2 |
N |
D |
? |
CL3,NBD1 |
p.Met
577
Val
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
CL3,NBD1 |
p.Glu
602
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
CL3,NBD1 |
p.Glu
602
Cys
|
details |
homologous mutations |
1 |
27 |
33 |
D |
D |
? |
CL3,NBD1 |
p.Glu
602
Asp
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
CL3,NBD1 |
p.Glu
602
Arg
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
CL3,NBD1,SIG1 |
p.Leu
607
Ala
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
CL3,NBD1,SIG1 |
p.Ala
609
Gly
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
CL3,NBD1,SIG1 |
p.Ala
609
Val
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
CL3,NBD1,SIG1 |
p.Gly
610
Asp
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
CL3,NBD1,SIG1 |
p.Gly
610
Val
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
CL3,NBD1 |
p.Glu
632
Gln
|
details |
homologous mutations |
2 |
115 |
215 |
D |
D |
? |
CL3,NBD1 |
p.Glu
632
Asp
|
details |
homologous mutations |
1 |
27 |
51 |
D |
N |
? |
CL3,NBD1 |
p.Cys
641
Ser
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
CL3,NBD1 |
p.Arg
651
Cys
|
details |
homologous mutations |
8 |
18 |
19 |
N |
N |
? |
CL3,NBD1 |
p.Arg
651
Trp
|
details |
homologous mutations |
1 |
1 |
1 |
D |
N |
? |
CL3,NBD1 |
p.Thr
655
Ala
|
details |
homologous mutations |
1 |
1 |
2 |
D |
D |
? |
CL3,NBD1 |
p.Val
656
Leu
|
details |
homologous mutations |
1 |
7 |
11 |
N |
N |
? |
CL3,NBD1 |
p.Val
656
Ala
|
details |
homologous mutations |
1 |
4 |
4 |
N |
D |
? |
CL3,NBD1 |
p.His
661
Ala
|
details |
homologous mutations |
1 |
27 |
36 |
D |
D |
? |
CL3,NBD1 |
p.His
661
Gln
|
details |
homologous mutations |
1 |
24 |
42 |
D |
D |
? |
CL3,NBD1 |
p.Arg
662
Leu
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Thr
665
Ala
|
details |
homologous mutations |
11 |
18 |
19 |
D |
D |
? |