ABCB3 p.Gly338Ala
| Predicted by SNAP2: | A: N (53%), C: D (63%), D: D (71%), E: D (85%), F: D (91%), H: D (75%), I: D (85%), K: D (91%), L: D (85%), M: D (85%), N: N (72%), P: D (91%), Q: D (80%), R: D (91%), S: N (82%), T: D (80%), V: D (85%), W: D (85%), Y: D (91%), |
| Predicted by PROVEAN: | A: N, C: D, D: D, E: D, F: D, H: D, I: D, K: D, L: D, M: D, N: D, P: D, Q: D, R: D, S: N, T: D, V: D, W: D, Y: D, |
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[hide] The biology of the P-glycoproteins. J Membr Biol. 1995 Jan;143(2):89-102. Leveille-Webster CR, Arias IM
The biology of the P-glycoproteins.
J Membr Biol. 1995 Jan;143(2):89-102., [PMID:7731035]
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No. Sentence Comment
207 Mutation of glycine 338 to alanine and alanine 339 to proline in transmembrane domain 6 in hamster p-glycoprotein decreased resistance to several drugs while maintaining normal resistance to actinomycin D [63].
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ABCB3 p.Gly338Ala 7731035:207:12
status: NEW