ABCMdb

Mutations at homologous positions to ABCD1 p.Gly512

Alignment: ABCD_full, Alignment of full length ABCD proteins, 2012-10-21 21:20:27

Mutations exactly at the same position:

		SNAP2 PROVEAN Effect_dbs
ABCD1	p.Gly512Cys details p.Gly512Ser details p.Gly512Asp details	D D ? D D ? D D ?
ABCD3	p.Gly478Arg details	D D ?

Mutations +/- 5 a.a. around the position:

ABCD1	p.Gly507Asp details p.Gly507Val details p.Pro508Leu details p.Asn509Ile details p.Gly510Asp details p.Gly510Ser details p.Cys511* details p.Lys513Gln details p.Lys513Arg details p.Ser514Asn details p.Ser514Ile details p.Ser514Arg details p.Ser514His details p.Ser515Phe details p.Ser515Tyr details p.Leu516Pro details	D D ? D D ? D D ? D D ? D D ? D D ? - - ? D D ? D D ? D D ? D D ? D D ? D D ? D D D D D ? D D ?
ABCD3	p.Lys479Ala details	D D ?
ABCD4	p.Lys427Leu details	D D ?

The alignment around the queried position:

565
ABCD1 474

I

N

I

V

T

S

G

-

V

V

V

A

S

L

N

I

R

V

E

E

G

H

L

I

T

F

I

L

G

P

T

G

G

-

-

-

V

L

Y

P

P

Q

R

M

Y

I

P

M

S

549
ABCD2 478

I

I

C

E

N

V

I

I

T

P

A

G

E

-

V

V

A

S

R

L

N

F

K

V

E

E

G

M

H

L

L

I

T

G

P

N

G

C

G

K

S

S

L

F

R

I

L

S

G

L

W

P

V

Y

E

G

-

-

-

V

L

Y

K

P

P

P

Q

H

M

F

Y

I

P

Q

R

P

Y

M

S

553
ABCD3 440

I

K

F

D

H

V

P

L

A

T

P

N

G

D

-

V

L

I

R

D

L

N

F

E

V

S

G

A

N

V

L

I

C

G

P

N

G

C

S

S

L

F

R

V

L

G

E

L

W

P

L

F

G

G

-

-

-

R

L

T

K

P

E

R

G

K

L

F

Y

V

P

Q

R

P

Y

M

T

515
ABCD4 387

F

L

L

E

R

V

S

I

S

A

P

S

S

D

K

P

L

I

K

D

L

S

L

K

I

S

E

G

Q

S

L

L

I

T

G

N

T

G

T

G

T

S

L

L

R

V

L

G

G

L

W

T

S

T

R

G

S

V

Q

M

L

T

D

F

G

P

H

G

V

L

F

L

P

Q

K

P

F

F

T

466