Mutations at homologous positions to ABCC8 p.Cys1174

Alignment: ABCC_full, Alignment of full length ABCC proteins, 2016-02-18 11:19:27

Mutations exactly at the same position:

Mutations +/- 5 a.a. around the position:

The alignment around the queried position:

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1465
ABCC8 1135
I
P
S
T
L
E
L
S
R
S
T
C
V
S
A
L
A
V
I
S
Y
V
T
P
V
F
L
V
L
L
P
L
A
I
V
Y
F
I
K
Y
F
V
R
D
L
Q
L
D
T
T
L
L
L
H
F
E
T
V
E
G
T
T
I
R
1214
ABCC1 1087
I
V
I
M
F
M
G
L
F
V
I
G
A
I
V
I
L
L
A
T
I
A
A
I
I
I
L
G
L
I
Y
F
F
V
Q
F
Y
V
A
S
Q
L
L
S
S
R
S
V
Y
S
H
F
T
L
L
V
S
I
1166
ABCC2 1095
L
P
Q
S
L
S
W
I
T
C
F
G
I
I
S
T
L
V
M
I
C
M
T
P
V
F
T
I
I
V
I
P
L
G
I
I
Y
V
S
V
Q
M
F
Y
V
S
T
S
R
Q
L
R
L
D
S
V
T
R
S
I
Y
S
H
F
S
E
T
V
S
G
L
P
V
1174
ABCC3 1083
L
A
P
V
I
L
M
L
L
N
S
F
F
N
A
I
S
T
L
V
V
I
M
A
S
T
P
L
F
T
V
V
I
L
P
L
A
V
L
Y
T
L
V
Q
R
F
Y
A
A
T
S
R
Q
L
K
L
E
S
V
S
R
S
P
I
Y
S
H
F
S
E
T
V
T
G
A
S
V
I
R
1162
ABCC4 836
L
P
L
T
F
L
D
F
I
Q
T
L
L
Q
V
V
G
V
S
V
A
V
A
V
I
P
W
I
A
P
L
V
P
L
G
I
I
F
I
F
L
R
R
Y
F
L
E
T
S
R
D
V
K
R
L
E
S
T
T
R
S
P
F
S
H
L
S
S
S
L
Q
G
L
W
T
I
R
915
ABCC5 986
L
P
F
Q
A
E
M
F
I
Q
N
V
I
L
V
F
F
C
V
G
M
I
A
G
V
F
P
W
F
L
V
A
V
G
P
L
V
I
L
F
S
V
L
H
I
V
S
R
V
L
I
R
E
L
K
R
L
D
N
I
T
Q
S
P
F
L
S
H
I
T
S
S
I
Q
G
L
A
T
I
H
1065
ABCC6 1059
I
P
D
K
S
L
L
M
Y
A
F
G
L
L
E
V
S
L
V
V
A
V
A
T
P
L
A
T
V
A
I
L
P
L
F
L
L
Y
A
G
F
Q
S
L
Y
V
V
S
S
C
Q
L
R
L
E
S
A
S
Y
S
V
C
S
H
A
E
F
Q
S
T
V
V
1138
ABCC7 987
L
P
L
T
F
I
Q
L
L
I
V
I
G
A
V
V
L
Q
I
V
A
T
V
V
F
L
A
F
L
Q
S
Q
Q
L
L
E
S
P
I
L
S
L
1066
ABCC9 1107
I
P
P
T
L
E
S
L
T
S
T
L
L
C
L
S
A
I
G
I
S
Y
A
T
P
V
F
L
V
A
L
L
P
L
G
V
A
F
Y
F
I
Q
K
Y
F
V
A
S
K
D
L
Q
E
L
D
D
S
T
Q
L
P
L
L
C
H
F
S
E
T
A
E
G
L
T
T
I
R
1186
ABCC10 1039
L
P
F
I
L
N
I
L
L
A
N
A
G
L
L
G
L
L
A
V
L
G
S
G
L
P
W
L
L
L
L
L
P
P
L
S
I
M
Y
Y
H
V
Q
R
H
Y
R
A
S
S
R
E
L
R
R
L
G
S
L
T
L
S
P
L
Y
S
H
L
A
D
T
L
A
G
L
S
V
L
R
1118
ABCC11 934
L
P
I
F
S
E
Q
F
L
V
L
S
L
M
V
I
A
V
L
L
I
V
S
V
L
S
P
Y
I
L
L
M
G
A
I
I
M
V
I
C
F
I
Y
Y
M
M
F
K
K
A
I
G
V
F
K
R
L
E
Y
S
R
S
P
L
F
S
H
I
L
N
S
L
Q
G
L
S
S
I
H
1013
ABCC12 923
L
P
F
H
A
E
N
F
L
Q
Q
F
F
M
V
V
F
I
L
V
I
L
A
A
V
F
P
A
V
L
L
V
V
A
S
L
A
V
G
F
F
I
L
L
R
I
F
H
R
G
V
Q
E
L
K
K
V
E
N
V
S
R
S
P
W
F
T
H
I
T
S
S
M
Q
G
L
G
I
I
H
1002