Mutations at homologous positions to ABCC2 p.Arg1230

Alignment: ABCC_full, Alignment of full length ABCC proteins, 2016-02-18 11:19:27

Mutations exactly at the same position:

Mutations +/- 5 a.a. around the position:

The alignment around the queried position:

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 1561
ABCC2 1191
D
T
N
Q
K
C
V
F
S
W
I
T
S
N
R
W
L
A
I
R
L
E
L
V
G
N
L
T
V
F
F
S
A
L
M
M
V
I
Y
R
D
T
-
-
L
S
G
D
T
V
G
F
V
L
S
N
A
L
N
I
T
Q
T
L
N
W
L
V
R
M
T
S
E
I
E
T
N
I
V
A
 1268
ABCC1 1183
D
E
N
Q
K
A
Y
Y
P
S
I
V
A
N
R
W
L
A
V
R
L
E
C
V
G
N
C
I
V
L
F
A
A
L
F
A
V
I
S
R
H
S
-
-
L
S
A
G
L
V
G
L
S
V
S
Y
S
L
Q
V
T
T
Y
L
N
W
L
V
R
M
S
S
E
M
E
T
N
I
V
A
 1260
ABCC3 1179
D
A
N
Q
R
S
C
Y
P
Y
I
I
S
N
R
W
L
S
I
G
V
E
F
V
G
N
C
V
V
L
F
A
A
L
F
A
V
I
G
R
S
S
-
-
L
N
P
G
L
V
G
L
S
V
S
Y
S
L
Q
V
T
F
A
L
N
W
M
I
R
M
M
S
D
L
E
S
N
I
V
A
 1256
ABCC4 932
D
L
H
S
E
A
W
F
L
F
L
T
T
S
R
W
F
A
V
R
L
D
A
I
C
A
M
F
V
I
I
V
A
F
G
S
L
I
L
A
K
T
-
-
L
D
A
G
Q
V
G
L
A
L
S
Y
A
L
T
L
M
G
M
F
Q
W
C
V
R
Q
S
A
E
V
E
N
M
M
I
S
 1009
ABCC5 1082
D
D
N
Q
A
P
F
F
L
F
T
C
A
M
R
W
L
A
V
R
L
D
L
I
S
I
A
L
I
T
T
T
G
L
M
I
V
L
M
H
G
Q
-
-
I
P
P
A
Y
A
G
L
A
I
S
Y
A
V
Q
L
T
G
L
F
Q
F
T
V
R
L
A
S
E
T
E
A
R
F
T
S
 1159
ABCC6 1155
D
E
S
Q
R
I
S
F
P
R
L
V
A
D
R
W
L
A
A
N
V
E
L
L
G
N
G
L
V
F
A
A
A
T
C
A
V
L
S
K
A
H
-
-
L
S
A
G
L
V
G
F
S
V
S
A
A
L
Q
V
T
Q
T
L
Q
W
V
V
R
N
W
T
D
L
E
N
S
I
V
S
 1232
ABCC7 1083
N
L
H
T
A
N
W
F
L
Y
L
S
T
L
R
W
F
Q
M
R
I
E
M
I
F
V
I
F
F
I
A
V
T
F
I
S
I
L
T
T
G
E
-
-
-
G
E
G
R
V
G
I
I
L
T
L
A
M
N
I
M
S
T
L
Q
W
A
V
N
S
S
I
D
V
D
S
L
M
R
S
 1159
ABCC8 1231
D
S
N
N
I
A
S
L
F
L
T
A
A
N
R
W
L
E
V
R
M
E
Y
I
G
A
C
V
V
L
I
A
A
V
T
S
I
S
N
S
L
H
R
E
L
S
A
G
L
V
G
L
G
L
T
Y
A
L
M
V
S
N
Y
L
N
W
M
V
R
N
L
A
D
M
E
L
Q
L
G
A
 1310
ABCC9 1203
D
T
N
N
I
A
Y
L
F
L
S
A
A
N
R
W
L
E
V
R
T
D
Y
L
G
A
C
I
V
L
T
A
S
I
A
S
I
S
G
S
S
N
-
-
-
-
S
G
L
V
G
L
G
L
L
Y
A
L
T
I
T
N
Y
L
N
W
V
V
R
N
L
A
D
L
E
V
Q
M
G
A
 1278
ABCC10 1135
E
L
N
Q
R
C
Q
F
A
T
S
A
T
M
Q
W
L
D
I
R
L
Q
L
M
G
A
A
V
V
S
A
I
A
G
I
A
L
V
Q
H
Q
Q
G
L
A
N
P
G
L
V
G
L
S
L
S
Y
A
L
S
L
T
G
L
L
S
G
L
V
S
S
F
T
Q
T
E
A
M
L
V
S
 1214
ABCC11 1030
D
A
Q
N
N
Y
L
L
L
F
L
S
S
T
R
W
M
A
L
R
L
E
I
M
T
N
L
V
T
L
A
V
A
L
F
V
A
F
G
I
S
S
-
-
T
P
Y
S
F
K
V
M
A
V
N
I
V
L
Q
L
A
S
S
F
Q
A
T
A
R
I
G
L
E
T
E
A
Q
F
T
A
 1107
ABCC12 1013
-
-
-
-
Y
H
L
L
Y
F
N
C
A
L
R
W
F
A
L
R
M
D
V
L
M
N
I
L
T
F
T
V
A
L
L
V
T
L
S
F
S
S
-
-
I
S
T
S
S
K
G
L
S
L
S
Y
I
I
Q
L
S
G
L
L
Q
V
C
V
R
T
G
T
E
T
Q
A
K
F
T
S
 1086