Mutations at homologous positions to ABCC8 p.Ser1237

Alignment: ABCC_full, Alignment of full length ABCC proteins, 2016-02-18 11:19:27

Mutations exactly at the same position:

Mutations +/- 5 a.a. around the position:

The alignment around the queried position:

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 1528
ABCC8 1198
P
L
L
S
H
F
A
E
T
V
E
G
L
T
T
I
R
A
F
R
Y
E
A
R
F
Q
Q
K
L
L
E
Y
T
D
S
N
N
I
A
S
L
F
L
T
A
A
N
R
W
L
E
V
R
M
E
Y
I
G
A
C
V
V
L
I
A
A
V
T
S
I
S
N
S
L
H
R
E
L
S
A
 1277
ABCC1 1150
P
V
Y
S
H
F
N
E
T
L
L
G
V
S
V
I
R
A
F
E
E
Q
E
R
F
I
H
Q
S
D
L
K
V
D
E
N
Q
K
A
Y
Y
P
S
I
V
A
N
R
W
L
A
V
R
L
E
C
V
G
N
C
I
V
L
F
A
A
L
F
A
V
I
S
R
H
S
-
-
L
S
A
 1227
ABCC2 1158
P
I
Y
S
H
F
S
E
T
V
S
G
L
P
V
I
R
A
F
E
H
Q
Q
R
F
L
K
H
N
E
V
R
I
D
T
N
Q
K
C
V
F
S
W
I
T
S
N
R
W
L
A
I
R
L
E
L
V
G
N
L
T
V
F
F
S
A
L
M
M
V
I
Y
R
D
T
-
-
L
S
G
 1235
ABCC3 1146
P
I
Y
S
H
F
S
E
T
V
T
G
A
S
V
I
R
A
Y
N
R
S
R
D
F
E
I
I
S
D
T
K
V
D
A
N
Q
R
S
C
Y
P
Y
I
I
S
N
R
W
L
S
I
G
V
E
F
V
G
N
C
V
V
L
F
A
A
L
F
A
V
I
G
R
S
S
-
-
L
N
P
 1223
ABCC4 899
P
V
F
S
H
L
S
S
S
L
Q
G
L
W
T
I
R
A
Y
K
A
E
E
R
C
Q
E
L
F
D
A
H
Q
D
L
H
S
E
A
W
F
L
F
L
T
T
S
R
W
F
A
V
R
L
D
A
I
C
A
M
F
V
I
I
V
A
F
G
S
L
I
L
A
K
T
-
-
L
D
A
 976
ABCC5 1049
P
F
L
S
H
I
T
S
S
I
Q
G
L
A
T
I
H
A
Y
N
K
G
Q
E
F
L
H
R
Y
Q
E
L
L
D
D
N
Q
A
P
F
F
L
F
T
C
A
M
R
W
L
A
V
R
L
D
L
I
S
I
A
L
I
T
T
T
G
L
M
I
V
L
M
H
G
Q
-
-
I
P
P
 1126
ABCC6 1122
S
V
C
S
H
M
A
E
T
F
Q
G
S
T
V
V
R
A
F
R
T
Q
A
P
F
V
A
Q
N
N
A
R
V
D
E
S
Q
R
I
S
F
P
R
L
V
A
D
R
W
L
A
A
N
V
E
L
L
G
N
G
L
V
F
A
A
A
T
C
A
V
L
S
K
A
H
-
-
L
S
A
 1199
ABCC7 1050
P
I
F
T
H
L
V
T
S
L
K
G
L
W
T
L
R
A
F
G
R
Q
P
Y
F
E
T
L
F
H
K
A
L
N
L
H
T
A
N
W
F
L
Y
L
S
T
L
R
W
F
Q
M
R
I
E
M
I
F
V
I
F
F
I
A
V
T
F
I
S
I
L
T
T
G
E
-
-
-
G
E
 1126
ABCC9 1170
P
L
L
C
H
F
S
E
T
A
E
G
L
T
T
I
R
A
F
R
H
E
T
R
F
K
Q
R
M
L
E
L
T
D
T
N
N
I
A
Y
L
F
L
S
A
A
N
R
W
L
E
V
R
T
D
Y
L
G
A
C
I
V
L
T
A
S
I
A
S
I
S
G
S
S
N
-
-
-
-
S
 1245
ABCC10 1102
P
L
Y
S
H
L
A
D
T
L
A
G
L
S
V
L
R
A
T
G
A
T
Y
R
F
E
E
E
N
L
R
L
L
E
L
N
Q
R
C
Q
F
A
T
S
A
T
M
Q
W
L
D
I
R
L
Q
L
M
G
A
A
V
V
S
A
I
A
G
I
A
L
V
Q
H
Q
Q
G
L
A
N
P
 1181
ABCC11 997
P
L
F
S
H
I
L
N
S
L
Q
G
L
S
S
I
H
V
Y
G
K
T
E
D
F
I
S
Q
F
K
R
L
T
D
A
Q
N
N
Y
L
L
L
F
L
S
S
T
R
W
M
A
L
R
L
E
I
M
T
N
L
V
T
L
A
V
A
L
F
V
A
F
G
I
S
S
-
-
T
P
Y
 1074
ABCC12 986
P
W
F
T
H
I
T
S
S
M
Q
G
L
G
I
I
H
A
Y
G
K
K
E
S
C
I
T
-
-
-
-
-
-
-
-
-
-
Y
H
L
L
Y
F
N
C
A
L
R
W
F
A
L
R
M
D
V
L
M
N
I
L
T
F
T
V
A
L
L
V
T
L
S
F
S
S
-
-
I
S
T
 1053