Mutations at homologous positions to ABCB1 p.Phe938

Alignment: ABCB_halves, Alignment of ABC subunits from proteins in the ABCB subfamily, 2011-11-21 18:43:41

Mutations exactly at the same position:

		SNAP2 PROVEAN Effect_dbs
ABCB1	p.Ala295Cys details p.Phe938Ala details p.Phe938Cys details	N D ? N D ? D D ?
ABCB3	p.Arg373Cys details	D D ?

Mutations +/- 5 a.a. around the position:

ABCB1	p.Ile293Cys details p.Thr294Cys details p.Thr294Ala details p.Asn296Cys details p.Asn296Ala details p.Ile297Cys details p.Ile297Arg details p.Ser298Cys details p.Ser298Ala details p.Ser298Arg details p.Ile299Met details p.Ile299Cys details p.Gly300Val details p.Ala935Cys details p.His936Cys details p.Ile937Ser details p.Ile937Cys details p.Gly939Val details p.Gly939Cys details p.Ile940Ser details p.Ile940Cys details p.Thr941Ala details p.Thr941Cys details p.Thr941Gly details p.Phe942Ala details p.Phe942Cys details p.Phe942Arg details p.Ser943Ala details p.Ser943Cys details	N D ? D D ? N N ? D D ? D D ? N D ? D D ? N D ? N N ? D D ? N N ? N N ? D D ? D D ? D D ? D D ? N D ? D D ? D D ? N D ? N D ? N N ? N N ? N D ? D D ? D D ? D D ? N N ? N D ?
ABCB11	p.Gly327Glu details p.Asn979Asp details p.Gly982Arg details	D D ? N N ? D D ?
ABCB2	p.Lys463Ala details p.Ala465Val details	D D ? D D ?
ABCB3	p.Ala374Asp details p.Ala374Thr details	D D ? D D ?
ABCB4	p.Ile299Met details p.Ile299Cys details p.Met301Thr details p.Gly302Ala details p.Ala934Thr details p.Ile936Ala details p.Phe941Ser details	N N ? N D ? N D ? D D ? D D ? N D ? D D ?

The alignment around the queried position:

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

1042
ABCB1 673

R

G

S

Q

A

Q

D

R

K

L

S

T

K

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E

A

L

D

E

S

I

P

P

V

S

F

W

R

I

M

K

L

N

L

T

E

W

P

Y

-

711
ABCB1 1281

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1281
ABCB2 809

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809
ABCB3 687

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687
ABCB4 672

K

N

S

Q

M

C

Q

K

S

L

D

V

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T

D

G

L

E

A

N

V

P

P

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F

L

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F

711
ABCB4 1287

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1287
ABCB5 813

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813
ABCB6 843

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843
ABCB7 753

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753
ABCB8 736

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736
ABCB9 767

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767
ABCB10 739

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739
ABCB11 716

D

H

K

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Y

E

E

D

R

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755
ABCB11 1322

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1322

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