ABCB1 p.Phe942Ala

Predicted by SNAP2: A: D (66%), C: D (53%), D: D (85%), E: D (85%), G: D (75%), H: D (71%), I: D (71%), K: D (85%), L: D (59%), M: N (57%), N: D (66%), P: D (85%), Q: D (71%), R: D (85%), S: D (66%), T: D (75%), V: D (71%), W: D (75%), Y: N (82%),
Predicted by PROVEAN: A: D, C: D, D: D, E: D, G: D, H: D, I: D, K: D, L: D, M: D, N: D, P: D, Q: D, R: D, S: D, T: D, V: D, W: D, Y: N,

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[hide] Loo TW, Clarke DM
Identification of residues in the drug-binding domain of human P-glycoprotein. Analysis of transmembrane segment 11 by cysteine-scanning mutagenesis and inhibition by dibromobimane.
J Biol Chem. 1999 Dec 10;274(50):35388-92., 1999-12-10 [PMID:10585407]

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[hide] Gozalpour E, Wittgen HG, van den Heuvel JJ, Greupink R, Russel FG, Koenderink JB
Interaction of digitalis-like compounds with p-glycoprotein.
Toxicol Sci. 2013 Feb;131(2):502-11. doi: 10.1093/toxsci/kfs307. Epub 2012 Oct 26., [PMID:23104431]

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[hide] Gozalpour E, Greupink R, Bilos A, Verweij V, van den Heuvel JJ, Masereeuw R, Russel FG, Koenderink JB
Convallatoxin: a new P-glycoprotein substrate.
Eur J Pharmacol. 2014 Dec 5;744:18-27. doi: 10.1016/j.ejphar.2014.09.031. Epub 2014 Sep 28., [PMID:25264938]

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