Mutations at homologous positions to ABCC7 p.Asp1370
Alignment: ABCC_full, Alignment of full length ABCC proteins, 2016-02-18 11:19:27Mutations exactly at the same position:
|
SNAP2 PROVEAN Effect_dbs |
||
|---|---|---|
| ABCC7 |
p.Asp1370Asn
|
D
D
?
|
| ABCC1 |
p.Asp1454Leu
p.Asp1454Asn
|
D
D
?
D
D
?
|
| ABCC8 |
p.Asp1505Asn
p.Asp1505His
|
D
D
?
D
D
?
|
Mutations +/- 5 a.a. around the position:
| ABCC7 |
p.Ile1366Thr
p.Ile1366Phe
p.Ile1366Asn
p.Leu1367Ile
p.Glu1371*
p.Glu1371Ser
p.Glu1371Gln
p.Glu1371Ala
p.Pro1372Leu
p.Ala1374Cys
p.His1375Ala
p.His1375Asn
p.His1375Pro
|
D
D
?
D
D
?
D
D
?
N
N
?
-
-
D
D
D
D
D
N
D
D
D
D
D
D
?
D
D
?
N
N
?
N
N
D
N
|
| ABCC1 |
p.Glu1455Leu
p.Glu1455Asp
p.Glu1455Ser
p.Glu1455Gln
p.Glu1455Asn
p.Ala1459Thr
|
D
D
?
D
D
?
D
D
?
D
D
?
D
D
?
D
D
?
|
| ABCC4 |
p.Glu1202Ala
|
D
D
?
|
| ABCC6 |
p.Ile1424Thr
p.Glu1427Lys
|
N
D
D
D
D
?
|
| ABCC8 |
p.Ser1500Ala
p.Ser1500Arg
p.Glu1506Lys
p.Glu1506Asp
p.Glu1506Gly
p.Glu1506Gln
|
N
N
?
N
N
?
D
D
?
D
D
?
D
D
?
D
D
?
|
The alignment around the queried position:
1813ABCC7 1331
F
P
G
K
V
G
G
V
M
L
A
S
V
L
S
K
K
L
L
S
L
P
I
R
R
T
K
A
A
I
A
L
1410
ABCC1 1415
L
P
D
K
L
D
H
E
A
E
G
G
E
N
S
Q
Q
V
L
A
R
A
L
L
R
K
T
K
I
L
V
L
A
T
A
V
D
L
E
T
D
D
L
I
Q
S
T
I
R
T
Q
F
E
D
T
V
L
T
I
A
R
N
T
D
Y
1494
ABCC2 1422
L
Q
L
G
L
S
H
E
V
T
E
A
G
G
N
L
S
I
G
Q
R
Q
L
L
L
G
R
L
L
R
K
S
K
I
L
V
L
D
E
A
T
A
A
V
D
L
E
T
D
N
L
I
Q
T
I
Q
N
E
F
A
H
C
T
V
I
T
I
H
R
L
H
T
I
M
D
S
1501
ABCC3 1411
Q
P
A
G
L
D
F
Q
C
S
E
G
E
N
L
S
V
G
Q
R
Q
L
V
C
L
A
R
A
L
L
R
K
S
R
I
L
V
L
D
E
A
T
A
A
I
D
L
E
T
D
N
L
I
Q
A
T
I
R
T
Q
F
D
T
C
V
L
T
I
A
H
R
L
N
T
I
M
D
Y
1490
ABCC4 1162
L
P
G
K
M
D
T
E
L
A
E
G
S
N
F
S
V
G
Q
R
Q
L
V
C
L
A
R
A
I
L
R
K
N
Q
I
L
I
I
D
A
T
A
N
V
D
P
R
T
D
E
L
I
Q
K
K
I
E
K
F
A
H
C
T
V
L
T
I
A
H
R
L
N
T
I
I
D
S
1241
ABCC5 1315
L
P
L
K
L
E
S
E
V
M
E
N
G
D
N
F
S
V
G
E
R
Q
L
L
C
I
A
R
A
L
L
R
H
C
K
I
L
I
L
D
E
A
T
A
A
M
D
T
E
T
D
L
L
I
Q
E
T
I
R
E
A
F
A
D
C
T
M
L
I
A
H
R
L
H
T
V
L
S
1394
ABCC6 1387
L
P
G
Q
L
Q
Y
C
A
D
G
D
L
V
K
Q
L
L
C
L
A
R
A
L
K
T
Q
I
L
L
D
A
T
A
A
V
D
P
G
T
E
L
Q
M
Q
A
M
L
G
S
W
F
A
Q
C
T
V
L
L
I
A
H
L
S
V
M
D
C
1466
ABCC8 1466
L
P
G
L
A
I
I
T
E
E
N
F
Q
R
Q
L
F
C
L
A
A
F
V
R
K
T
I
F
I
M
A
T
A
S
I
M
A
E
N
I
L
Q
V
M
T
A
F
A
D
V
V
T
I
A
R
V
H
I
S
A
1545
ABCC9 1434
L
P
G
G
L
D
A
V
V
T
E
G
G
E
N
F
S
V
G
Q
R
Q
L
F
C
L
A
R
F
V
R
K
S
S
I
L
I
M
D
E
A
T
A
S
I
D
M
A
T
E
N
I
L
Q
K
V
V
M
T
A
F
A
D
R
T
V
V
T
I
A
H
R
V
S
S
I
M
D
1513
ABCC10 1368
M
G
G
-
L
D
G
E
L
G
E
G
G
R
S
L
S
L
Q
R
Q
L
L
C
L
A
R
A
L
L
T
D
A
K
I
L
C
I
D
E
A
T
A
S
V
D
Q
K
T
D
Q
L
L
Q
Q
T
I
C
K
R
F
A
N
K
T
V
L
T
I
A
H
R
L
N
T
I
L
N
S
1446
ABCC11 1263
F
P
K
K
L
H
T
D
V
V
E
N
G
G
N
F
S
V
G
E
R
Q
L
L
C
I
A
R
A
V
L
R
N
S
K
I
I
L
I
D
E
A
T
A
S
I
D
M
E
T
D
T
L
I
Q
R
T
I
R
E
A
F
Q
G
C
T
V
L
V
I
A
H
R
V
T
T
V
L
N
C
1342
ABCC12 1242
L
P
E
K
L
Q
A
E
V
T
E
N
G
E
N
F
S
V
G
E
R
Q
L
L
C
V
A
R
A
L
L
R
N
S
K
I
I
L
L
D
E
A
T
A
S
M
D
S
K
D
T
L
V
Q
N
T
I
K
D
A
F
K
G
C
T
V
L
T
I
A
H
R
L
N
T
V
L
N
C
1321