Mutations at homologous positions to ABCC1 p.Pro1113
Alignment: ABCC_full, Alignment of full length ABCC proteins, 2016-02-18 11:19:27Mutations exactly at the same position:
SNAP2 PROVEAN Effect_dbs |
||
---|---|---|
ABCC1 |
p.Pro1113Ala
|
D
D
?
|
ABCC7 |
p.Pro1013Leu
p.Pro1013His
|
D
D
D
D
D
|
Mutations +/- 5 a.a. around the position:
ABCC2 |
p.Ala1119Thr
|
N
N
?
|
ABCC4 |
p.Ile866Val
|
D
N
?
|
ABCC7 |
p.Val1008Asp
p.Ala1009Thr
p.Tyr1014Cys
p.Phe1016Ser
|
D
D
N
N
D
D
D
N
|
ABCC8 |
p.Ala1166Cys
|
N
N
?
|
The alignment around the queried position:
ABCC1 1074
N
R
F
S
K
E
L
D
V
M
I
V
I
M
F
M
G
L
F
V
I
G
A
I
V
I
L
L
A
T
I
A
A
I
I
I
L
G
L
I
Y
F
F
V
Q
F
Y
V
A
S
Q
L
L
S
S
R
S
V
Y
S
1153
ABCC2 1082
N
R
F
A
G
D
I
S
T
V
D
D
T
L
P
Q
S
L
S
W
I
T
C
F
G
I
I
S
T
L
V
M
I
C
M
T
P
V
F
T
I
I
V
I
P
L
G
I
I
Y
V
S
V
Q
M
F
Y
V
S
T
S
R
Q
L
R
L
D
S
V
T
R
S
I
Y
S
1161
ABCC3 1070
N
C
F
S
K
D
I
Y
V
V
D
E
V
L
A
P
V
I
L
M
L
L
N
S
F
F
N
A
I
S
T
L
V
V
I
M
A
S
T
P
L
F
T
V
V
I
L
P
L
A
V
L
Y
T
L
V
Q
R
F
Y
A
A
T
S
R
Q
L
K
L
E
S
V
S
R
S
P
I
Y
S
1149
ABCC4 823
N
R
F
S
K
D
I
G
H
L
D
D
L
L
P
L
T
F
L
D
F
I
Q
T
L
L
Q
V
V
G
V
S
V
A
V
A
V
I
P
W
I
A
P
L
V
P
L
G
I
I
F
I
F
L
R
R
Y
F
L
E
T
S
R
D
V
K
R
L
E
S
T
T
R
S
P
F
S
902
ABCC5 973
N
R
F
S
K
D
M
D
E
V
D
V
R
L
P
F
Q
A
E
M
F
I
Q
N
V
I
L
V
F
F
C
V
G
M
I
A
G
V
F
P
W
F
L
V
A
V
G
P
L
V
I
L
F
S
V
L
H
I
V
S
R
V
L
I
R
E
L
K
R
L
D
N
I
T
Q
S
P
F
L
S
1052
ABCC6 1046
N
R
F
K
E
T
D
T
V
V
D
I
P
D
K
S
L
L
M
Y
A
F
G
L
L
E
V
S
L
V
V
A
V
A
T
P
L
A
T
V
A
I
L
P
L
F
L
L
Y
A
G
F
Q
S
L
Y
V
V
S
S
C
Q
L
R
L
E
S
A
S
Y
S
V
C
S
1125
ABCC7 974
N
F
A
I
L
D
L
L
P
L
T
F
I
Q
L
L
I
V
I
G
A
V
V
L
Q
I
V
A
T
V
V
F
L
A
F
L
Q
S
Q
Q
L
L
E
S
P
I
1053
ABCC8 1122
R
F
S
S
D
N
I
D
Q
H
I
P
S
T
L
E
L
S
R
S
T
C
V
S
A
L
A
V
I
S
Y
V
T
P
V
F
L
V
L
L
P
L
A
I
V
Y
F
I
K
Y
F
V
R
D
L
Q
L
D
T
T
L
L
L
1201
ABCC9 1094
N
R
F
S
A
D
T
N
I
I
D
Q
H
I
P
P
T
L
E
S
L
T
S
T
L
L
C
L
S
A
I
G
I
S
Y
A
T
P
V
F
L
V
A
L
L
P
L
G
V
A
F
Y
F
I
Q
K
Y
F
V
A
S
K
D
L
Q
E
L
D
D
S
T
Q
L
P
L
L
C
1173
ABCC10 1026
N
R
F
S
S
D
V
A
C
A
D
D
S
L
P
F
I
L
N
I
L
L
A
N
A
G
L
L
G
L
L
A
V
L
G
S
G
L
P
W
L
L
L
L
L
P
P
L
S
I
M
Y
Y
H
V
Q
R
H
Y
R
A
S
S
R
E
L
R
R
L
G
S
L
T
L
S
P
L
Y
S
1105
ABCC11 921
N
C
F
A
G
D
L
E
Q
L
D
Q
L
L
P
I
F
S
E
Q
F
L
V
L
S
L
M
V
I
A
V
L
L
I
V
S
V
L
S
P
Y
I
L
L
M
G
A
I
I
M
V
I
C
F
I
Y
Y
M
M
F
K
K
A
I
G
V
F
K
R
L
E
Y
S
R
S
P
L
F
S
1000
ABCC12 910
N
R
F
S
K
D
M
D
E
L
D
V
R
L
P
F
H
A
E
N
F
L
Q
Q
F
F
M
V
V
F
I
L
V
I
L
A
A
V
F
P
A
V
L
L
V
V
A
S
L
A
V
G
F
F
I
L
L
R
I
F
H
R
G
V
Q
E
L
K
K
V
E
N
V
S
R
S
P
W
F
T
989