Mutations at homologous positions to ABCA4 p.Glu2132

Alignment: ABCA_full, Alignment of full length ABCA proteins, 2016-02-18 11:17:15

Mutations exactly at the same position:

Mutations +/- 5 a.a. around the position:

The alignment around the queried position:

 
 
5303
ABCA4 2094
L
P
T
T
G
M
P
Q
A
M
L
N
V
V
S
I
I
-
G
R
A
V
V
L
T
S
C
E
A
L
T
A
M
V
K
A
F
M
G
T
I
Q
H
L
K
S
F
G
D
G
Y
V
T
M
K
I
2172
ABCA1 2068
L
D
E
P
T
M
K
A
R
F
L
W
N
C
A
L
S
V
K
E
-
G
R
S
V
V
L
T
S
H
S
M
E
E
C
E
L
C
T
R
M
A
I
M
V
N
G
R
F
R
C
L
G
S
V
Q
H
L
K
N
R
F
G
D
G
Y
T
I
V
V
I
A
2146
ABCA2 2209
L
D
E
P
T
T
G
M
D
P
K
A
R
R
F
L
W
N
L
I
L
D
L
I
K
T
-
G
R
S
V
V
L
T
S
H
S
M
E
E
C
E
A
L
C
T
R
L
A
I
M
V
N
G
R
L
R
C
L
G
S
I
Q
H
L
K
N
R
F
G
D
G
Y
M
I
T
V
R
T
K
2287
ABCA3 1538
L
D
E
P
S
T
G
M
D
P
V
A
R
W
D
T
V
A
R
A
E
S
-
G
K
A
I
I
I
T
S
H
S
M
E
E
C
A
C
T
L
A
I
M
G
F
K
C
G
S
P
Q
H
L
K
S
K
F
G
S
Y
S
L
A
K
V
Q
1616
ABCA5 1457
D
E
P
S
T
G
M
D
P
K
A
K
Q
H
M
W
R
A
I
R
T
A
F
K
N
R
K
R
A
A
I
L
T
T
H
Y
M
E
E
A
E
A
V
C
D
R
V
A
I
M
V
S
G
Q
L
R
C
I
G
T
V
Q
H
L
K
S
K
F
G
K
G
Y
F
L
E
I
K
L
K
D
1536
ABCA6 1437
D
E
P
S
T
G
I
D
P
T
G
Q
Q
Q
M
W
Q
A
I
Q
A
V
V
K
N
T
E
R
G
V
L
L
T
T
H
N
L
A
E
A
E
A
L
C
D
R
V
A
I
M
V
S
G
R
L
R
C
I
G
S
I
Q
H
L
K
N
K
L
G
K
D
Y
I
L
E
L
K
V
K
E
1516
ABCA7 1949
L
D
E
T
T
G
M
D
P
S
A
R
R
F
L
W
N
S
L
L
A
V
V
R
E
-
G
R
S
V
M
L
T
S
H
S
M
E
E
C
E
A
L
C
S
R
L
A
I
V
N
G
R
F
R
C
L
G
S
P
Q
H
L
G
R
F
A
A
G
H
T
L
T
L
R
V
P
2027
ABCA8 1402
D
E
P
S
T
G
M
D
P
E
G
Q
Q
Q
M
W
Q
A
I
R
A
T
F
R
N
T
E
R
G
A
L
L
T
T
H
Y
M
A
E
A
E
A
V
C
D
R
V
A
I
M
V
S
G
R
L
R
C
I
G
S
I
Q
H
L
K
S
K
F
G
K
D
Y
L
L
E
M
K
V
K
N
1481
ABCA9 1445
D
E
P
S
T
G
M
D
P
E
G
Q
Q
Q
M
W
Q
V
I
R
A
T
F
R
N
T
E
R
G
A
L
L
T
T
H
Y
M
A
E
A
E
A
V
C
D
R
V
A
I
M
V
S
G
R
L
R
C
I
G
S
I
Q
H
L
K
S
K
F
G
K
D
Y
L
L
E
M
K
L
K
N
1524
ABCA10 1364
D
E
P
F
T
G
M
D
P
E
G
Q
Q
Q
M
W
Q
I
L
Q
A
T
V
K
N
K
E
R
G
T
L
L
T
T
H
Y
M
S
E
A
E
A
V
C
D
R
M
A
M
M
V
S
G
T
L
R
C
I
G
S
I
Q
H
L
K
N
K
F
G
R
D
Y
L
L
E
I
K
M
K
E
1443
ABCA12 2413
L
D
E
P
S
S
G
M
D
P
K
S
K
R
H
L
W
K
I
I
S
E
E
V
Q
N
-
K
C
S
V
I
L
T
S
H
S
M
E
E
C
E
A
L
C
T
R
A
I
M
V
N
G
K
F
Q
C
I
G
S
L
Q
H
I
K
S
F
G
R
G
F
T
V
K
V
H
L
K
2491
ABCA13 4880
L
D
E
P
S
S
G
M
D
P
C
S
K
R
Y
L
W
Q
T
I
M
K
E
V
R
E
-
G
C
A
A
V
L
T
S
H
S
M
E
E
C
E
A
L
C
T
R
L
A
I
M
V
N
G
S
F
K
C
L
G
S
P
Q
H
I
K
N
R
F
G
D
G
Y
T
V
K
V
W
L
C
4958