Mutations in ABCC3
reference sequence
Region |
Mutation |
|
|
Publications |
Sentences |
MutMiner_hits |
SNAP2 |
PROVEAN |
Effect_ExpVar |
ELa |
p.Gly
11
Asp
|
details |
homologous mutations |
4 |
14 |
14 |
N |
N |
? |
ELa |
p.Lys
13
Asn
|
details |
homologous mutations |
3 |
8 |
10 |
N |
N |
? |
ELa |
p.Ser
17
Gly
|
details |
homologous mutations |
1 |
17 |
18 |
N |
N |
? |
ELa |
p.Ser
17
Ala
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
ELa |
p.Ser
17
Asp
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
TMD0,CLa |
p.His
68
Tyr
|
details |
homologous mutations |
7 |
14 |
14 |
N |
N |
? |
TMD0,ELb |
p.Arg
99
Gln
|
details |
homologous mutations |
2 |
9 |
9 |
N |
N |
? |
TMD0,THc |
p.Val
104
Met
|
details |
homologous mutations |
1 |
1 |
1 |
D |
N |
? |
TMD0,ELc |
p.Asp
167
Arg
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
CL0,L0 |
p.Arg
248
Gln
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
CL0 |
p.Thr
306
Ile
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
CL0 |
p.Gly
308
Val
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,EL1 |
p.Ser
346
Phe
|
details |
homologous mutations |
6 |
26 |
26 |
D |
D |
? |
TMD1,EL1 |
p.Ser
346
Ile
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
TMD1,CL1 |
p.Ala
403
Cys
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
TMD1,TH4 |
p.Pro
450
Arg
|
details |
homologous mutations |
1 |
1 |
4 |
D |
D |
? |
TMD1,CL2 |
p.Gln
513
Lys
|
details |
homologous mutations |
4 |
10 |
10 |
N |
N |
? |
TMD1,CL2 |
p.Arg
518
*
|
details |
homologous mutations |
1 |
1 |
1 |
- |
- |
? |
TMD1,CL2 |
p.Arg
518
Gln
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,CL2 |
p.Thr
527
Arg
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
TMD1,CL2 |
p.Ala
528
Gly
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
TMD1,TH5 |
p.Leu
548
Gln
|
details |
homologous mutations |
3 |
8 |
8 |
D |
D |
? |
TMD1,TH5 |
p.Thr
550
Ala
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3 |
p.Ser
607
Asn
|
details |
homologous mutations |
3 |
18 |
18 |
N |
N |
? |
CL3,NBD1 |
p.Gly
676
Arg
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Gly
689
Ala
|
details |
homologous mutations |
3 |
5 |
5 |
D |
D |
? |
CL3,NBD1 |
p.Lys
718
Met
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
CL3,NBD1 |
p.Thr
742
Cys
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
CL3,NBD1,SIG1 |
p.Val
765
Leu
|
details |
homologous mutations |
4 |
13 |
13 |
N |
N |
? |
CL3,NBD1 |
p.Asp
770
Asn
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Val
799
Met
|
details |
homologous mutations |
3 |
7 |
7 |
N |
N |
? |
CL3,NBD1 |
p.Thr
809
Met
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Val
829
Ile
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
CL3 |
p.Pro
920
Ser
|
details |
homologous mutations |
3 |
12 |
12 |
N |
N |
? |
CL3 |
p.Arg
923
Gln
|
details |
homologous mutations |
3 |
12 |
12 |
N |
N |
? |
TMD2,TH7 |
p.Ser
993
Cys
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD2,CL5 |
p.Arg
1138
Gln
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD2,CL5 |
p.Ile
1173
Phe
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
TMD2,EL6 |
p.Ser
1219
Arg
|
details |
homologous mutations |
3 |
9 |
9 |
N |
N |
? |
TMD2,TH12 |
p.Ser
1229
Ala
|
details |
homologous mutations |
1 |
7 |
7 |
N |
N |
? |
TMD2,TH12 |
p.Ser
1231
Ala
|
details |
homologous mutations |
1 |
7 |
7 |
D |
N |
? |
TMD2,TH12 |
p.Tyr
1232
Phe
|
details |
homologous mutations |
1 |
8 |
8 |
D |
D |
? |
TMD2,TH12 |
p.Ser
1233
Ala
|
details |
homologous mutations |
1 |
7 |
7 |
N |
N |
? |
TMD2,TH12 |
p.Gln
1235
Ala
|
details |
homologous mutations |
1 |
14 |
14 |
D |
D |
? |
TMD2,TH12 |
p.Thr
1237
Ala
|
details |
homologous mutations |
1 |
21 |
21 |
D |
D |
? |
TMD2,TH12 |
p.Thr
1237
Ser
|
details |
homologous mutations |
1 |
6 |
6 |
N |
D |
? |
TMD2,TH12 |
p.Thr
1237
Leu
|
details |
homologous mutations |
1 |
6 |
6 |
D |
D |
? |
TMD2,TH12 |
p.Thr
1237
Gly
|
details |
homologous mutations |
1 |
8 |
8 |
D |
D |
? |
TMD2,TH12 |
p.Asn
1241
Ala
|
details |
homologous mutations |
1 |
8 |
8 |
D |
D |
? |
CL6 |
p.Trp
1242
Phe
|
details |
homologous mutations |
1 |
20 |
20 |
D |
D |
? |
CL6 |
p.Trp
1242
Cys
|
details |
homologous mutations |
1 |
20 |
20 |
D |
D |
? |
CL6 |
p.Trp
1242
Ala
|
details |
homologous mutations |
2 |
22 |
22 |
D |
D |
? |
CL6 |
p.Trp
1242
Pro
|
details |
homologous mutations |
1 |
12 |
12 |
D |
D |
? |
CL6 |
p.Trp
1242
Tyr
|
details |
homologous mutations |
1 |
24 |
24 |
D |
D |
? |
CL6 |
p.Arg
1286
Gly
|
details |
homologous mutations |
3 |
12 |
12 |
D |
N |
? |
CL6,NBD2 |
p.Arg
1297
His
|
details |
homologous mutations |
20 |
99 |
113 |
D |
D |
? |
CL6,NBD2 |
p.Pro
1300
Leu
|
details |
homologous mutations |
1 |
2 |
2 |
N |
D |
? |
CL6,NBD2 |
p.Gly
1316
Ala
|
details |
homologous mutations |
2 |
2 |
2 |
N |
D |
? |
CL6,NBD2 |
p.Val
1322
Phe
|
details |
homologous mutations |
2 |
13 |
13 |
D |
D |
? |
CL6,NBD2 |
p.Arg
1348
Cys
|
details |
homologous mutations |
4 |
14 |
14 |
N |
N |
? |
CL6,NBD2 |
p.Asp
1361
Asn
|
details |
homologous mutations |
1 |
1 |
1 |
N |
D |
? |
CL6,NBD2 |
p.Leu
1362
Val
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
CL6,NBD2 |
p.Gln
1365
Arg
|
details |
homologous mutations |
4 |
13 |
13 |
D |
N |
? |
CL6,NBD2 |
p.Arg
1381
Ser
|
details |
homologous mutations |
4 |
35 |
40 |
D |
D |
? |
CL6,NBD2 |
p.Ala
1398
Val
|
details |
homologous mutations |
1 |
2 |
2 |
N |
D |
? |
CL6,NBD2 |
p.Thr
1406
Met
|
details |
homologous mutations |
3 |
8 |
8 |
N |
N |
? |
CL6,NBD2 |
p.Gly
1423
Arg
|
details |
homologous mutations |
4 |
11 |
11 |
D |
D |
? |
CL6,NBD2 |
p.Thr
1476
Met
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL6,NBD2 |
p.Arg
1492
Trp
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL6,NBD2 |
p.Ala
1513
Asp
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |