Mutations in ABCC4
reference sequence
Region |
Mutation |
|
|
Publications |
Sentences |
MutMiner_hits |
SNAP2 |
PROVEAN |
Effect_ExpVar |
CL0,L0 |
p.Leu
18
Ile
|
details |
homologous mutations |
2 |
4 |
5 |
N |
N |
? |
CL0,L0 |
p.His
35
Asp
|
details |
homologous mutations |
1 |
4 |
4 |
D |
D |
? |
CL0,L0 |
p.Ser
46
Asn
|
details |
homologous mutations |
1 |
3 |
3 |
N |
N |
? |
CL0,L0 |
p.Trp
64
Arg
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL0 |
p.Pro
78
Ala
|
details |
homologous mutations |
3 |
10 |
12 |
D |
D |
? |
TMD1,TH2 |
p.Ala
134
Ser
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
TMD1,CL1 |
p.Val
159
Met
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
TMD1,CL1 |
p.Cys
171
Gly
|
details |
homologous mutations |
2 |
6 |
6 |
D |
D |
? |
TMD1,CL1 |
p.His
172
Gln
|
details |
homologous mutations |
1 |
1 |
1 |
N |
D |
? |
TMD1,CL1 |
p.Met
173
Thr
|
details |
homologous mutations |
1 |
1 |
1 |
N |
D |
? |
TMD1,CL1 |
p.Met
184
Thr
|
details |
homologous mutations |
2 |
3 |
4 |
N |
N |
? |
TMD1,CL1 |
p.Met
184
Val
|
details |
homologous mutations |
2 |
2 |
2 |
N |
N |
? |
TMD1,CL1 |
p.Gly
187
Trp
|
details |
homologous mutations |
8 |
49 |
58 |
D |
D |
? |
TMD1,CL2 |
p.Arg
262
Lys
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,CL2 |
p.Lys
293
Glu
|
details |
homologous mutations |
3 |
5 |
6 |
N |
D |
? |
TMD1,CL2 |
p.Lys
304
Asn
|
details |
homologous mutations |
11 |
34 |
37 |
N |
N |
? |
TMD1,TH6 |
p.Thr
356
Met
|
details |
homologous mutations |
2 |
3 |
4 |
N |
N |
? |
TMD1,TH6 |
p.Thr
364
Arg
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
TMD1,TH6 |
p.Phe
368
Leu
|
details |
homologous mutations |
1 |
8 |
10 |
N |
D |
? |
TMD1,TH6 |
p.Phe
368
Trp
|
details |
homologous mutations |
1 |
39 |
51 |
D |
D |
? |
TMD1,TH6 |
p.Phe
368
Tyr
|
details |
homologous mutations |
1 |
11 |
13 |
N |
N |
? |
TMD1,TH6 |
p.Phe
368
Ala
|
details |
homologous mutations |
1 |
4 |
4 |
N |
D |
? |
CL3 |
p.Glu
374
Ser
|
details |
homologous mutations |
1 |
9 |
11 |
N |
N |
? |
CL3 |
p.Arg
375
Ser
|
details |
homologous mutations |
1 |
27 |
29 |
N |
N |
? |
CL3 |
p.Arg
375
Glu
|
details |
homologous mutations |
1 |
9 |
9 |
D |
N |
? |
CL3 |
p.Arg
375
Ala
|
details |
homologous mutations |
1 |
10 |
10 |
D |
N |
? |
CL3 |
p.Arg
375
Lys
|
details |
homologous mutations |
1 |
8 |
8 |
N |
N |
? |
CL3 |
p.Glu
378
Gln
|
details |
homologous mutations |
1 |
8 |
10 |
D |
D |
? |
CL3 |
p.Pro
403
Leu
|
details |
homologous mutations |
4 |
10 |
14 |
D |
D |
? |
CL3,NBD1,WA1 |
p.Gly
445
Cys
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
CL3,NBD1 |
p.Tyr
477
Trp
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Gly
487
Glu
|
details |
homologous mutations |
5 |
34 |
38 |
D |
D |
? |
CL3,NBD1 |
p.Lys
498
Glu
|
details |
homologous mutations |
5 |
13 |
15 |
N |
N |
? |
CL3,NBD1 |
p.Arg
531
Gln
|
details |
homologous mutations |
3 |
10 |
12 |
D |
D |
? |
CL3,NBD1,SIG1 |
p.Gly
538
Asp
|
details |
homologous mutations |
1 |
5 |
5 |
D |
D |
? |
CL3,NBD1,SIG1 |
p.Gly
538
Ala
|
details |
homologous mutations |
2 |
7 |
7 |
D |
D |
? |
CL3,NBD1,SIG1 |
p.Ala
548
Gly
|
details |
homologous mutations |
1 |
1 |
1 |
N |
D |
? |
CL3,NBD1,WB1 |
p.Tyr
556
Cys
|
details |
homologous mutations |
5 |
33 |
35 |
D |
D |
? |
CL3,NBD1,WB1 |
p.Leu
557
Pro
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Glu
575
Lys
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Thr
587
Gly
|
details |
homologous mutations |
1 |
1 |
1 |
N |
D |
? |
CL3,NBD1 |
p.Ala
600
Pro
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL3,NBD1 |
p.Ile
625
Met
|
details |
homologous mutations |
2 |
3 |
4 |
D |
N |
? |
CL3 |
p.Ser
664
Phe
|
details |
homologous mutations |
1 |
1 |
1 |
N |
D |
? |
CL3 |
p.Pro
667
Leu
|
details |
homologous mutations |
2 |
3 |
4 |
N |
D |
? |
CL3 |
p.Gln
677
Arg
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
TMD2,EL4 |
p.Met
744
Val
|
details |
homologous mutations |
4 |
9 |
13 |
D |
N |
? |
TMD2,EL4 |
p.Glu
757
Lys
|
details |
homologous mutations |
12 |
30 |
35 |
D |
N |
? |
TMD2,TH8 |
p.Val
776
Ile
|
details |
homologous mutations |
4 |
29 |
33 |
N |
N |
? |
TMD2,CL4 |
p.Ser
794
Leu
|
details |
homologous mutations |
1 |
6 |
6 |
D |
D |
? |
TMD2,CL4 |
p.Thr
796
Met
|
details |
homologous mutations |
1 |
83 |
117 |
N |
D |
? |
TMD2,CL4 |
p.His
798
Tyr
|
details |
homologous mutations |
1 |
4 |
4 |
D |
D |
? |
TMD2,CL4 |
p.Met
801
Val
|
details |
homologous mutations |
1 |
1 |
1 |
N |
D |
? |
TMD2,CL4 |
p.Arg
815
Ala
|
details |
homologous mutations |
1 |
14 |
20 |
N |
N |
? |
TMD2,CL4 |
p.Arg
820
Ile
|
details |
homologous mutations |
4 |
11 |
12 |
D |
D |
? |
TMD2,TH9 |
p.Val
854
Phe
|
details |
homologous mutations |
6 |
22 |
25 |
D |
D |
? |
TMD2,TH10 |
p.Ile
866
Val
|
details |
homologous mutations |
4 |
10 |
12 |
D |
N |
? |
TMD2,CL5 |
p.Val
900
Leu
|
details |
homologous mutations |
2 |
3 |
4 |
D |
N |
? |
TMD2,TH11 |
p.Cys
956
Ser
|
details |
homologous mutations |
3 |
14 |
16 |
D |
D |
? |
CL6 |
p.Trp
995
Phe
|
details |
homologous mutations |
1 |
11 |
13 |
D |
D |
? |
CL6 |
p.Trp
995
Ala
|
details |
homologous mutations |
1 |
4 |
4 |
D |
D |
? |
CL6 |
p.Trp
995
Tyr
|
details |
homologous mutations |
1 |
12 |
14 |
D |
D |
? |
CL6 |
p.Arg
998
Ala
|
details |
homologous mutations |
2 |
7 |
7 |
D |
D |
? |
CL6 |
p.Arg
998
Lys
|
details |
homologous mutations |
2 |
3 |
3 |
D |
N |
? |
CL6 |
p.Arg
998
Glu
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL6 |
p.Arg
998
Leu
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
CL6 |
p.Arg
998
Ser
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
CL6 |
p.Arg
998
Tyr
|
details |
homologous mutations |
1 |
2 |
2 |
D |
D |
? |
CL6,NBD2 |
p.Thr
1062
Cys
|
details |
homologous mutations |
1 |
1 |
1 |
N |
D |
? |
CL6,NBD2 |
p.Ala
1063
Gly
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
CL6,NBD2 |
p.Val
1071
Ile
|
details |
homologous mutations |
4 |
17 |
18 |
N |
N |
? |
CL6,NBD2,WA2 |
p.Lys
1081
Asn
|
details |
homologous mutations |
1 |
3 |
3 |
D |
D |
? |
CL6,NBD2 |
p.Leu
1084
Lys
|
details |
homologous mutations |
2 |
2 |
3 |
D |
D |
? |
CL6,NBD2 |
p.Ile
1103
Val
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
CL6,NBD2 |
p.Arg
1114
Cys
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL6,NBD2 |
p.Pro
1121
Ala
|
details |
homologous mutations |
1 |
1 |
2 |
D |
D |
? |
CL6,NBD2 |
p.Thr
1130
Met
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL6,NBD2 |
p.Thr
1142
Met
|
details |
homologous mutations |
8 |
18 |
21 |
D |
D |
? |
CL6,NBD2 |
p.Ser
1173
Ala
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
CL6,NBD2 |
p.Glu
1202
Ala
|
details |
homologous mutations |
1 |
1 |
1 |
D |
D |
? |
CL6,NBD2 |
p.Arg
1220
Gln
|
details |
homologous mutations |
3 |
4 |
5 |
N |
D |
? |
CL6,NBD2 |
p.Ser
1267
Gly
|
details |
homologous mutations |
1 |
2 |
2 |
N |
N |
? |
CL6,NBD2 |
p.Met
1272
Val
|
details |
homologous mutations |
1 |
2 |
4 |
N |
D |
? |
CL6 |
p.Lys
1289
Arg
|
details |
homologous mutations |
1 |
1 |
1 |
N |
N |
? |
CL6 |
p.Gln
1314
Arg
|
details |
homologous mutations |
2 |
3 |
4 |
N |
N |
? |
CL6 |
p.Leu
1325
Ala
|
details |
homologous mutations |
1 |
8 |
9 |
D |
N |
? |