ABCC4 p.Tyr477Trp

Predicted by SNAP2: A: D (75%), C: D (71%), D: D (91%), E: D (91%), F: D (53%), G: D (85%), H: D (75%), I: D (66%), K: D (91%), L: D (53%), M: D (75%), N: D (85%), P: D (95%), Q: D (85%), R: D (91%), S: D (85%), T: D (85%), V: D (71%), W: D (80%),
Predicted by PROVEAN: A: D, C: D, D: D, E: D, F: D, G: D, H: D, I: D, K: D, L: D, M: D, N: D, P: D, Q: D, R: D, S: D, T: D, V: D, W: D,

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[hide] Ambudkar SV, Kim IW, Xia D, Sauna ZE
The A-loop, a novel conserved aromatic acid subdomain upstream of the Walker A motif in ABC transporters, is critical for ATP binding.
FEBS Lett. 2006 Feb 13;580(4):1049-55. Epub 2005 Dec 22., [PMID:16412422]

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