Mutations at homologous positions to ABCC6 p.Arg760

Alignment: ABCC_full, Alignment of full length ABCC proteins, 2016-02-18 11:19:27

Mutations exactly at the same position:

		SNAP2 PROVEAN Effect_dbs
ABCC6	p.Arg760Trp details p.Arg760Gln details	D D D D D D
ABCC2	p.Arg768Trp details p.Arg768Tyr details	D D D D D D
ABCC7	p.Arg553* details p.Arg553Gln details p.Arg553Gly details p.Arg553Met details p.Arg553Lys details p.Arg553Cys details p.Arg553Asp details	- - D D N D D D D D D D N D D D D D D D
ABCC8	p.Arg836* details p.Arg836* details	- - D - - D

Mutations +/- 5 a.a. around the position:

ABCC6	p.Gly755Arg details p.Arg765Gln details p.Arg765Trp details	D D D D D D D D D
ABCC1	p.Gly771Asp details p.Gly771Ala details	D D ? D D ?
ABCC4	p.Gly538Asp details p.Gly538Ala details	D D ? D D ?
ABCC7	p.Leu548Gln details p.Leu548Cys details p.Ser549Arg details p.Ser549Asn details p.Ser549Ile details p.Ser549Cys details p.Ser549Lys details p.Gly550Glu details p.Gly550His details p.Gly550Asp details p.Gly550Arg details p.Gly550* details p.Gly551Asp details p.Gly551Ser details p.Gly551Ala details p.Gly551Cys details p.Gly551Arg details p.Gly551* details p.Gly551Glu details p.Gly551Lys details p.Gln552* details p.Gln552His details p.Gln552Ala details p.Gln552Cys details p.Ala554Glu details p.Arg555Lys details p.Arg555Gln details p.Arg555Thr details p.Arg555Gly details p.Arg555Ala details p.Ile556Val details p.Leu558Ser details	D D ? D D ? N D D N D D D D D D D D D D D D D ? D D ? D D ? D D - - D D D N D D D D D D D D D D D - - D D D D D D D - - D D D D D D D D D D N N ? D D ? D D ? D D ? D D D D ? N N D D D
ABCC8	p.Arg834Trp details p.Arg841* details p.Arg841Gly details	D D ? - - ? D D ?

The alignment around the queried position:

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

989
ABCC6 721

W

L

E

R

V

L

E

A

C

A

L

Q

P

D

V

D

S

F

P

E

G

I

H

T

S

I

G

E

Q

G

M

N

L

S

G

G

Q

K

Q

R

L

S

L

A

R

A

V

Y

R

K

A

A

V

Y

L

L

D

D

P

L

A

A

L

D

A

H

V

G

Q

H

V

F

N

Q

V

I

G

P

G

G

800
ABCC1 736

Y

Y

R

S

V

I

Q

A

C

A

L

L

P

D

L

E

I

L

P

S

G

D

R

T

E

I

G

E

K

G

V

N

L

S

G

G

Q

K

Q

R

V

S

L

A

R

A

V

Y

S

N

A

D

I

Y

L

F

D

D

P

L

S

A

V

D

A

H

V

G

K

H

I

F

E

N

V

I

G

P

K

G

815
ABCC2 729

R

Y

Q

Q

V

L

E

A

C

A

L

L

P

D

L

E

M

L

P

G

G

D

L

A

E

I

G

E

K

G

I

N

L

S

G

G

Q

K

Q

R

I

S

L

A

R

A

T

Y

Q

N

L

D

I

Y

L

L

D

D

P

L

S

A

V

D

A

H

V

G

K

H

I

F

N

K

V

L

G

P

N

G

808
ABCC3 719

R

Y

Q

Q

T

L

E

A

C

A

L

L

A

D

L

E

M

L

P

G

G

D

Q

T

E

I

G

E

K

G

I

N

L

S

G

G

Q

R

Q

R

V

S

L

A

R

A

V

Y

S

D

A

D

I

F

L

L

D

D

P

L

S

A

V

D

S

H

V

A

K

H

I

F

D

H

V

I

G

P

E

G

798
ABCC4 503

R

Y

E

K

V

I

K

A

C

A

L

K

K

D

L

Q

L

L

E

D

G

D

L

T

V

I

G

D

R

G

T

T

L

S

G

G

Q

K

A

R

V

N

L

A

R

A

V

Y

Q

D

A

D

I

Y

L

L

D

D

P

L

S

A

V

D

A

E

V

S

R

H

L

F

E

L

C

I

C

Q

I

-

582
ABCC5 653

R

Y

N

S

V

L

N

S

C

C

L

R

P

D

L

A

I

L

P

S

S

D

L

T

E

I

G

E

R

G

A

N

L

S

G

G

Q

R

Q

R

I

S

L

A

R

A

L

Y

S

D

R

S

I

Y

I

L

D

D

P

L

S

A

L

D

A

H

V

G

N

H

I

F

N

S

A

I

R

K

H

-

732
ABCC7 514

E

Y

R

Y

R

S

V

I

K

A

C

Q

L

E

E

D

I

S

K

F

A

E

K

D

N

I

V

L

G

E

G

G

I

T

L

S

G

G

Q

R

A

R

I

S

L

A

R

A

V

Y

K

D

A

D

L

Y

L

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D

S

P

F

G

Y

L

D

V

L

T

E

K

E

I

F

E

S

C

V

C

K

593
ABCC8 797

R

Y

K

M

V

I

E

A

C

S

L

Q

P

D

I

D

I

L

P

H

G

D

Q

T

Q

I

G

E

R

G

I

N

L

S

G

G

Q

R

Q

R

I

S

V

A

R

A

L

Y

Q

H

A

N

V

V

F

L

D

D

P

F

S

A

L

D

I

H

L

S

D

H

L

M

Q

A

G

I

L

E

L

L

876
ABCC9 780

R

Y

K

A

V

T

D

A

C

S

L

Q

P

D

I

D

L

L

P

F

G

D

Q

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E

I

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E

R

G

I

N

L

S

G

G

Q

R

Q

R

I

C

V

A

R

A

L

Y

Q

N

T

N

I

V

F

L

D

D

P

F

S

A

L

D

I

H

L

S

D

H

L

M

Q

E

G

I

L

K

F

L

859
ABCC10 694

L

Y

K

E

V

L

E

A

C

A

L

N

D

D

L

S

I

L

P

A

G

D

Q

T

E

V

G

E

K

G

V

T

L

S

G

G

Q

R

A

R

I

A

L

A

R

A

V

Y

Q

E

K

E

L

Y

L

L

D

D

P

L

A

A

V

D

A

D

V

A

N

H

L

L

H

R

C

I

L

G

M

L

773
ABCC11 602

R

Y

L

Q

V

L

H

C

C

S

L

N

R

D

L

E

L

L

P

F

G

D

M

T

E

I

G

E

R

G

L

N

L

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G

G

Q

K

Q

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A

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A

V

Y

S

D

R

Q

I

Y

L

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D

D

P

L

S

A

V

D

A

H

V

G

K

H

I

F

E

E

C

I

K

K

T

-

681
ABCC12 571

R

Y

Q

H

T

V

R

V

C

G

L

Q

K

D

L

S

N

L

P

Y

G

D

L

T

E

I

G

E

R

G

L

N

L

S

G

G

Q

R

Q

R

I

S

L

A

R

A

V

Y

S

D

R

Q

L

Y

L

L

D

D

P

L

S

A

V

D

A

H

V

G

K

H

V

F

E

E

C

I

K

K

T

-

650

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