Mutations at homologous positions to ABCC7 p.Gln1352
Alignment: ABCC_full, Alignment of full length ABCC proteins, 2016-02-18 11:19:27Mutations exactly at the same position:
|
SNAP2 PROVEAN Effect_dbs |
||
|---|---|---|
| ABCC7 |
p.Gln1352His
p.Gln1352Glu
|
D
D
D
D
N
?
|
Mutations +/- 5 a.a. around the position:
| ABCC7 |
p.Ser1347Cys
p.Ser1347Gly
p.Ser1347Val
p.Ser1347Thr
p.His1348Gly
p.His1348Ala
p.Gly1349Asp
p.Gly1349Ser
p.Gly1349Ile
p.Gly1349Ala
p.His1350Gln
p.His1350Ala
p.Lys1351Glu
p.Lys1351Arg
p.Leu1353Met
p.Cys1355Ser
|
D
D
?
D
D
?
D
D
?
D
N
?
N
N
?
N
N
?
D
D
D
D
D
D
D
?
D
D
?
N
N
?
D
D
?
D
N
N
N
?
D
N
?
D
D
?
|
| ABCC1 |
p.Val1432Gly
p.Gly1433Asp
p.Gly1433Ala
p.Arg1435Gln
p.Leu1437Arg
p.Cys1439Ser
p.Cys1439Ala
|
D
D
?
D
D
?
D
D
?
D
D
?
D
D
?
N
D
?
N
D
?
|
| ABCC10 |
p.Gly1385Ala
|
D
D
?
|
| ABCC2 |
p.Cys1446Gly
|
D
D
?
|
| ABCC6 |
p.Ser1403Arg
p.Gly1405Ser
p.Gln1406Lys
|
D
D
D
D
D
D
D
D
D
|
| ABCC8 |
p.Ser1482Arg
p.Gly1484Arg
p.Gly1484Asp
p.Gln1485His
|
D
D
?
D
D
?
D
D
?
D
D
?
|
The alignment around the queried position:
1795ABCC7 1313
E
K
A
D
G
S
Q
F
P
G
K
V
G
G
V
M
L
A
S
V
L
S
K
K
L
L
S
L
P
I
R
R
T
K
A
1392
ABCC1 1397
E
E
V
W
S
L
E
L
A
H
L
K
D
F
V
S
A
L
P
D
K
L
D
H
E
A
E
G
G
E
N
S
Q
Q
V
L
A
R
A
L
L
R
K
T
K
I
L
V
L
A
T
A
V
D
L
E
T
D
D
L
I
Q
S
T
I
R
T
Q
F
1476
ABCC2 1404
E
E
I
W
K
A
L
E
L
A
L
K
S
F
V
A
S
L
Q
L
G
L
S
H
E
V
T
E
A
G
G
N
L
S
I
G
Q
R
Q
L
L
L
G
R
L
L
R
K
S
K
I
L
V
L
D
E
A
T
A
A
V
D
L
E
T
D
N
L
I
Q
T
I
Q
N
E
F
1483
ABCC3 1393
E
D
I
W
W
L
E
L
S
H
L
H
F
V
S
S
Q
P
A
G
L
D
F
Q
C
S
E
G
E
N
L
S
V
G
Q
R
Q
L
V
C
L
A
R
A
L
L
R
K
S
R
I
L
V
L
D
E
A
T
A
A
I
D
L
E
T
D
N
L
I
Q
A
T
I
R
T
Q
F
1472
ABCC4 1144
E
E
L
W
N
A
L
Q
E
V
Q
L
K
E
T
I
E
D
L
P
G
K
M
D
T
E
L
A
E
G
S
N
F
S
V
G
Q
R
Q
L
V
C
L
A
R
A
I
L
R
K
N
Q
I
L
I
I
D
A
T
A
N
V
D
P
R
T
D
E
L
I
Q
K
K
I
E
K
F
1223
ABCC5 1297
D
Q
I
W
D
A
L
E
R
T
H
M
K
E
C
I
A
Q
L
P
L
K
L
E
S
E
V
M
E
N
G
D
N
F
S
V
G
E
R
Q
L
L
C
I
A
R
A
L
L
R
H
C
K
I
L
I
L
D
E
A
T
A
A
M
D
T
E
T
D
L
L
I
Q
E
T
I
R
E
A
F
1376
ABCC6 1369
A
I
W
A
A
L
E
T
V
Q
L
K
A
L
V
A
S
L
P
G
Q
L
Q
Y
C
A
D
G
D
L
V
K
Q
L
L
C
L
A
R
A
L
K
T
Q
I
L
L
D
A
T
A
A
V
D
P
G
T
E
L
Q
M
Q
A
M
L
G
S
W
F
1448
ABCC8 1448
T
L
W
E
A
L
I
Q
L
K
L
V
V
K
A
L
P
G
L
A
I
I
T
E
E
N
F
Q
R
Q
L
F
C
L
A
A
F
V
R
K
T
I
F
I
M
A
T
A
S
I
M
A
E
N
I
L
Q
V
M
T
A
F
1527
ABCC9 1416
D
R
L
W
E
A
L
E
I
A
Q
L
K
N
M
V
K
S
L
P
G
G
L
D
A
V
V
T
E
G
G
E
N
F
S
V
G
Q
R
Q
L
F
C
L
A
R
F
V
R
K
S
S
I
L
I
M
D
E
A
T
A
S
I
D
M
A
T
E
N
I
L
Q
K
V
V
M
T
A
F
1495
ABCC10 1350
R
A
L
W
Q
A
L
K
Q
C
H
L
S
E
V
I
T
S
M
G
G
-
L
D
G
E
L
G
E
G
G
R
S
L
S
L
Q
R
Q
L
L
C
L
A
R
A
L
L
T
D
A
K
I
L
C
I
D
E
A
T
A
S
V
D
Q
K
T
D
Q
L
L
Q
Q
T
I
C
K
R
F
1428
ABCC11 1245
Q
Q
I
W
D
A
L
E
R
T
F
L
T
K
A
I
S
K
F
P
K
K
L
H
T
D
V
V
E
N
G
G
N
F
S
V
G
E
R
Q
L
L
C
I
A
R
A
V
L
R
N
S
K
I
I
L
I
D
E
A
T
A
S
I
D
M
E
T
D
T
L
I
Q
R
T
I
R
E
A
F
1324
ABCC12 1224
E
M
L
W
Q
V
L
E
R
T
F
M
R
D
T
I
M
K
L
P
E
K
L
Q
A
E
V
T
E
N
G
E
N
F
S
V
G
E
R
Q
L
L
C
V
A
R
A
L
L
R
N
S
K
I
I
L
L
D
E
A
T
A
S
M
D
S
K
D
T
L
V
Q
N
T
I
K
D
A
F
1303