Mutations at homologous positions to ABCA3 p.Val93
Alignment: ABCA_full, Alignment of full length ABCA proteins, 2016-02-18 11:17:15Mutations exactly at the same position:
SNAP2 PROVEAN Effect_dbs |
||
---|---|---|
ABCA3 |
p.Val93Ile
|
N
N
?
|
ABCA4 |
p.Val424Ala
|
N
N
?
|
Mutations +/- 5 a.a. around the position:
ABCA4 |
p.His423Arg
p.Lys429Arg
|
N
N
N
N
N
?
|
ABCA7 |
p.Glu316Lys
p.Thr319Ala
|
N
N
?
N
N
?
|
The alignment around the queried position:
ABCA3 67
-
-
-
-
-
-
-
-
-
-
-
-
-
L
F
F
T
F
P
G
D
T
W
E
L
A
Y
I
P
S
S
D
A
A
K
T
T
E
T
V
R
R
A
V
I
N
M
V
R
G
F
P
S
-
E
K
F
E
D
Y
I
R
Y
C
S
-
-
-
-
-
-
127
ABCA1 382
-
-
-
-
-
-
-
-
-
-
-
-
K
I
L
Y
T
P
D
T
P
A
T
R
Q
V
M
A
E
N
T
F
Q
E
L
A
V
F
H
D
L
E
G
W
E
E
L
S
P
K
I
T
F
M
E
-
N
S
Q
E
M
D
L
V
R
M
L
D
S
R
D
N
D
H
F
448
ABCA2 446
L
G
L
L
V
H
L
M
T
S
N
P
K
I
L
Y
A
P
A
G
S
E
V
D
R
V
I
L
K
A
N
E
T
F
A
F
V
G
N
V
T
H
Y
A
Q
V
W
L
N
I
S
A
E
I
R
S
F
L
E
-
Q
G
R
L
Q
Q
H
L
R
W
L
Q
Q
Y
V
A
E
L
R
L
524
ABCA4 397
-
-
-
-
-
-
-
-
-
-
-
-
K
I
L
Y
T
D
S
P
A
R
I
L
K
N
A
S
E
E
L
E
R
K
L
V
A
W
E
E
V
G
P
Q
I
W
Y
F
F
D
-
N
Q
N
M
I
R
D
T
L
G
N
P
T
V
K
D
F
463
ABCA5 1
-
-
-
-
-
-
-
-
-
-
M
S
T
A
I
R
E
V
G
V
W
R
Q
T
R
T
L
L
L
K
N
Y
L
I
K
C
R
T
K
K
S
S
V
Q
E
I
L
F
P
L
F
F
L
F
W
L
I
L
I
S
-
M
M
H
P
N
K
K
Y
E
E
V
P
N
I
E
L
N
-
-
68
ABCA6 1
-
-
-
-
-
-
-
-
-
-
-
-
M
N
M
K
Q
K
S
V
Y
Q
Q
T
K
A
L
L
C
K
N
F
L
K
K
W
R
M
K
R
E
S
L
L
E
W
G
L
S
I
L
L
G
L
C
I
A
L
F
S
-
S
S
M
R
N
V
Q
F
P
G
M
A
P
Q
N
L
G
-
-
66
ABCA7 294
-
-
-
-
-
-
-
-
-
-
-
-
K
L
L
F
A
P
D
T
P
F
T
R
K
L
M
A
Q
V
N
R
T
E
L
L
L
R
D
V
R
E
V
W
E
M
L
P
R
I
F
T
F
M
N
-
D
S
S
N
V
A
M
L
Q
R
L
L
Q
M
Q
D
E
G
-
-
359
ABCA8 1
-
-
-
-
-
-
-
-
-
-
-
-
M
R
K
R
K
I
S
V
C
Q
Q
T
W
A
L
L
C
K
N
F
L
K
K
W
R
M
K
R
E
S
L
M
E
W
L
N
S
L
L
L
L
L
C
L
Y
I
Y
P
-
H
S
H
Q
V
N
D
F
S
S
L
L
T
M
D
L
G
-
-
66
ABCA9 1
-
-
-
-
-
-
-
-
-
-
-
-
M
S
K
R
R
M
S
V
G
Q
Q
T
W
A
L
L
C
K
N
C
L
K
K
W
R
M
K
R
Q
T
L
L
E
W
L
F
S
F
L
L
V
L
F
L
Y
L
F
F
S
N
L
H
Q
V
H
D
T
P
Q
M
S
S
M
D
L
G
-
-
67
ABCA10 1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
ABCA12 808
-
-
-
-
-
-
-
-
-
-
-
-
R
I
L
Y
A
P
Y
N
P
V
T
K
A
I
M
E
K
S
N
V
T
L
R
Q
L
A
E
L
R
E
K
S
Q
E
W
M
D
K
S
P
L
F
M
N
S
F
H
L
L
N
Q
A
I
P
M
L
Q
N
T
L
R
N
P
F
V
Q
V
F
875
ABCA13 3317
-
-
-
-
-
-
-
-
-
-
-
-
K
I
L
Y
T
P
N
T
P
E
I
N
K
V
I
Q
K
A
N
Y
T
F
Y
I
V
D
K
L
K
T
L
S
E
T
L
L
E
M
S
S
L
F
Q
R
S
G
-
-
S
G
Q
M
F
N
Q
L
Q
E
A
L
R
N
K
F
V
R
N
F
3382