Mutations at homologous positions to ABCD1 p.Arg74
Alignment: ABCD_full, Alignment of full length ABCD proteins, 2012-10-21 21:20:27Mutations exactly at the same position:
|
SNAP2 PROVEAN Effect_dbs |
||
|---|---|---|
| ABCD1 |
p.Arg74Trp
p.Arg74Cys
p.Arg74Gly
|
D
D
?
D
D
?
D
D
?
|
| ABCD3 |
p.Arg66Ala
|
D
D
?
|
Mutations +/- 5 a.a. around the position:
| ABCD1 |
p.Phe71Ser
p.Phe71Val
p.Leu78Phe
|
D
D
?
D
D
?
D
D
?
|
| ABCD3 |
p.Lys61Ala
p.Val62Ala
p.Phe63Ala
p.Phe64Leu
p.Ser65Thr
p.Leu67Ala
p.Ile68Ala
p.Ile70Asn
p.Ile70Ala
p.Leu71Gln
p.Leu71Ala
|
N
N
?
N
N
?
D
D
?
N
N
?
N
N
?
D
D
?
N
N
?
D
D
?
N
D
?
D
D
?
N
D
?
|
| ABCD4 |
p.Leu21Asn
|
N
D
?
|
The alignment around the queried position:
ABCD1 43
A
R
G
L
A
P
A
G
E
P
T
Q
E
S
G
V
A
A
K
A
-
-
-
-
-
-
-
-
G
M
N
R
V
L
Q
L
L
W
L
R
L
F
R
V
L
R
T
G
L
L
L
H
A
L
F
V
Y
V
A
114
ABCD2 48
G
H
G
K
K
K
A
A
A
Y
P
A
A
E
N
T
E
I
L
H
C
T
E
T
I
C
E
K
P
S
P
G
V
N
A
D
F
F
K
Q
L
L
E
L
R
K
I
L
F
P
K
L
V
T
T
E
T
G
W
C
L
H
S
V
A
L
I
S
R
T
F
L
S
I
Y
V
A
G
L
127
ABCD3 39
-
-
-
-
-
-
S
G
K
P
P
L
Q
N
N
E
K
E
G
-
-
-
-
-
-
A
V
V
D
Q
I
M
V
T
F
C
K
V
I
A
V
M
L
V
T
Y
C
D
V
W
M
I
Q
N
106
ABCD4 1
-
-
-
-
-
M
A
V
A
G
P
A
P
G
A
G
A
R
P
-
-
-
-
-
-
-
-
-
-
-
-
R
L
D
L
Q
F
Q
R
F
L
Q
I
L
K
V
L
F
P
S
W
S
S
Q
N
A
L
M
F
L
T
L
L
C
L
T
L
L
E
Q
F
V
I
Y
Q
V
G
L
I
63