Mutations at homologous positions to ABCB11 p.Arg387

Alignment: ABCB_halves, Alignment of ABC subunits from proteins in the ABCB subfamily, 2011-11-21 18:43:41

Mutations exactly at the same position:

Mutations +/- 5 a.a. around the position:

The alignment around the queried position:

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 659
ABCB11 348
V
L
D
E
G
E
Y
T
P
G
T
L
V
Q
I
F
L
S
V
I
V
G
A
L
N
L
G
N
A
S
P
C
L
E
A
F
A
T
G
R
A
A
A
T
S
I
F
E
T
I
D
R
K
P
I
I
D
C
M
S
E
D
G
Y
K
L
D
R
-
I
K
G
E
I
E
F
H
N
V
T
 426
ABCB1 321
V
L
S
-
G
E
Y
S
I
G
Q
V
L
T
V
F
F
S
V
L
I
G
A
F
S
V
G
Q
A
S
P
S
I
E
A
F
A
N
A
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A
A
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F
K
I
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D
N
K
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I
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S
K
S
G
H
K
P
D
N
-
I
K
G
N
L
E
F
R
N
V
H
 398
ABCB1 964
V
A
H
-
K
L
M
S
F
E
D
V
L
L
V
F
S
A
V
V
F
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P
N
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-
L
E
G
N
V
T
F
G
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V
V
 1041
ABCB2 494
V
T
S
-
G
A
V
S
S
G
N
L
V
T
F
V
L
Y
Q
M
Q
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T
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P
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-
-
L
L
T
P
L
H
-
L
E
G
L
V
Q
F
Q
D
V
S
 569
ABCB3 399
M
Q
D
-
G
E
L
T
Q
G
S
L
L
S
F
M
I
Y
Q
E
S
V
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S
Y
V
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T
L
V
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I
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G
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L
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G
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A
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N
L
P
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P
G
-
-
T
L
A
P
T
T
-
L
Q
G
V
V
K
F
Q
D
V
S
 474
ABCB4 323
V
I
S
-
K
E
Y
T
I
G
N
A
M
T
V
F
F
S
I
L
I
G
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F
S
V
G
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A
A
P
C
I
D
A
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A
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A
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A
A
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I
F
D
I
I
D
N
N
P
K
I
D
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F
S
E
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G
H
K
P
D
S
-
I
K
G
N
L
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F
N
D
V
H
 400
ABCB4 963
I
V
N
-
G
H
M
R
F
R
D
V
I
L
V
F
S
A
I
V
F
G
A
V
A
L
G
H
A
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A
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S
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G
L
K
P
D
K
-
F
E
G
N
I
T
F
N
E
V
V
 1040
ABCB5 499
I
Q
A
-
G
R
M
T
P
E
G
M
F
I
V
F
T
A
I
A
Y
G
A
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A
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K
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D
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R
S
Q
E
G
K
K
P
D
T
-
C
E
G
N
L
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F
R
E
V
S
 576
ABCB6 520
V
T
E
-
Q
K
L
Q
V
G
D
Y
V
L
F
G
T
Y
I
I
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A
G
P
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-
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V
H
 596
ABCB7 400
I
V
A
-
G
T
L
T
V
G
D
L
V
M
V
N
G
L
L
F
Q
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T
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A
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D
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V
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 478
ABCB8 401
V
A
G
-
Q
Q
L
T
G
G
D
L
M
S
F
L
V
A
S
Q
T
V
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A
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L
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V
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C
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-
L
R
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V
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Q
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 478
ABCB9 435
V
I
S
-
G
Q
M
T
S
G
N
L
I
A
F
I
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Y
E
F
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A
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-
-
S
L
A
P
D
H
-
L
E
G
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V
D
F
E
N
V
T
 510
ABCB10 421
M
G
S
-
A
H
M
T
V
G
E
L
S
S
F
L
M
Y
A
F
W
V
G
I
S
I
G
G
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S
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Y
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L
G
A
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L
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L
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F
N
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G
V
I
L
N
E
K
S
-
F
Q
G
A
L
E
F
K
N
V
H
 498
ABCB11 1007
I
S
N
-
E
G
L
H
F
S
Y
V
F
R
V
I
S
A
V
V
L
S
A
T
A
L
G
R
A
F
S
Y
T
P
S
Y
A
K
A
K
I
S
A
A
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F
F
Q
L
L
D
R
Q
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P
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S
V
Y
N
T
A
G
E
K
W
D
N
-
F
Q
G
K
I
D
F
V
D
C
K
 1084