Mutations at homologous positions to ABCC7 p.Trp1310
Alignment: ABCC_full, Alignment of full length ABCC proteins, 2016-02-18 11:19:27Mutations exactly at the same position:
|
SNAP2 PROVEAN Effect_dbs |
||
|---|---|---|
| ABCC7 |
p.Trp1310*
p.Trp1310His
|
-
-
N
N
?
|
Mutations +/- 5 a.a. around the position:
| ABCC7 |
p.Asp1305Glu
p.Tyr1307Cys
p.Tyr1307Asn
p.Tyr1307*
p.Glu1308*
p.Glu1308Ala
p.Gln1309Lys
p.Gln1309Ala
p.Ser1311Lys
p.Ser1311Asn
p.Asp1312Gly
p.Gln1313*
p.Ile1315Met
|
D
D
N
D
N
N
?
-
-
-
-
N
N
?
N
N
?
N
N
?
N
N
?
N
N
?
D
D
-
-
D
N
N
?
|
| ABCC12 |
p.Asp1223Glu
|
N
N
?
|
| ABCC4 |
p.Thr1142Met
|
D
D
?
|
| ABCC6 |
p.Asp1361Asn
p.Glu1369Lys
|
N
D
D
D
D
?
|
| ABCC8 |
p.Ser1446Arg
p.Ser1446Ala
p.Ser1448Ala
|
D
D
?
D
N
?
N
N
?
|
The alignment around the queried position:
1753ABCC7 1271
G
V
S
W
D
S
I
T
L
A
V
I
I
S
G
F
R
L
P
E
K
A
D
G
S
Q
F
P
G
K
V
G
G
V
1350
ABCC1 1355
G
I
N
I
A
K
I
L
L
F
K
I
T
I
I
P
D
P
V
L
F
S
S
L
R
M
N
L
D
P
F
S
Q
Y
S
D
E
E
V
W
S
L
E
L
A
H
L
K
D
F
V
S
A
L
P
D
K
L
D
H
E
A
E
G
G
E
N
S
Q
1434
ABCC2 1362
G
V
D
I
A
I
G
L
H
D
R
E
K
L
T
I
I
D
P
I
L
F
S
G
S
L
M
N
L
D
P
F
N
N
Y
S
D
E
E
I
W
K
A
L
E
L
A
L
K
S
F
V
A
S
L
Q
L
G
L
S
H
E
V
T
E
A
G
G
N
L
S
I
G
Q
1441
ABCC3 1351
G
L
N
V
A
D
I
G
L
H
R
S
L
T
I
I
P
Q
D
P
I
L
F
S
G
T
L
M
N
L
D
P
F
G
S
Y
S
E
E
D
I
W
W
L
E
L
S
H
L
H
F
V
S
S
Q
P
A
G
L
D
F
Q
C
S
E
G
E
N
L
S
V
G
Q
1430
ABCC4 1102
K
L
T
T
E
I
G
L
H
D
L
K
K
M
S
I
I
Q
E
P
V
L
F
T
G
M
R
K
N
L
D
P
F
N
E
H
D
E
E
L
W
N
A
L
Q
E
V
Q
L
K
E
T
I
E
D
L
P
G
K
M
D
T
E
L
A
E
G
S
N
F
S
V
G
Q
1181
ABCC5 1255
G
V
R
I
S
D
I
G
L
A
D
L
R
S
K
L
S
I
I
P
Q
E
P
V
L
F
S
G
T
V
R
S
N
L
D
P
F
N
Q
Y
T
E
D
Q
I
W
D
A
L
E
R
T
H
M
K
E
C
I
A
Q
L
P
L
K
L
E
S
E
V
M
E
N
G
D
N
F
S
V
G
E
1334
ABCC6 1327
V
P
A
H
V
G
H
T
L
S
R
S
I
I
D
P
L
F
P
S
L
M
N
L
L
L
Q
E
H
S
D
A
I
W
A
A
L
E
T
V
Q
L
K
A
L
V
A
S
L
P
G
Q
L
Q
Y
C
A
D
G
D
L
V
1406
ABCC8 1406
G
I
D
I
A
K
L
L
H
T
L
R
S
L
S
I
L
D
P
V
L
F
S
T
I
F
N
L
D
P
E
R
K
C
D
T
L
W
E
A
L
I
Q
L
K
L
V
V
K
A
L
P
G
L
A
I
I
T
E
E
N
F
Q
1485
ABCC9 1374
G
I
D
I
S
K
L
P
L
H
T
L
R
S
R
L
S
I
I
L
Q
D
P
I
L
F
S
G
I
R
F
N
L
D
P
E
C
K
C
T
D
D
R
L
W
E
A
L
E
I
A
Q
L
K
N
M
V
K
S
L
P
G
G
L
D
A
V
V
T
E
G
G
E
N
F
S
V
G
Q
1453
ABCC10 1308
G
V
D
T
S
Q
L
E
L
A
Q
L
R
S
Q
L
A
I
I
P
Q
E
P
F
L
F
S
G
T
V
R
E
N
L
D
P
Q
G
L
H
K
D
R
A
L
W
Q
A
L
K
Q
C
H
L
S
E
V
I
T
S
M
G
G
-
L
D
G
E
L
G
E
G
G
R
S
L
S
L
Q
1386
ABCC11 1203
G
V
D
I
C
S
I
G
L
E
D
L
R
S
K
L
S
V
I
P
Q
D
P
V
L
L
S
G
T
I
R
F
N
L
D
P
F
D
R
H
T
D
Q
Q
I
W
D
A
L
E
R
T
F
L
T
K
A
I
S
K
F
P
K
K
L
H
T
D
V
V
E
N
G
G
N
F
S
V
G
E
1282
ABCC12 1182
E
V
D
I
C
I
L
S
L
E
D
L
R
T
K
L
T
V
I
P
Q
D
P
V
L
F
V
G
T
V
R
Y
N
L
D
P
F
E
S
H
T
E
M
L
W
Q
V
L
E
R
T
F
M
R
D
T
I
M
K
L
P
E
K
L
Q
A
E
V
T
E
N
G
E
N
F
S
V
G
E
1261