PMID: 23586520

Hazai E, Hazai I, Ragueneau-Majlessi I, Chung SP, Bikadi Z, Mao Q
Predicting substrates of the human breast cancer resistance protein using a support vector machine method.
BMC Bioinformatics. 2013 Apr 15;14:130. doi: 10.1186/1471-2105-14-130., [PubMed]
Sentences
No. Mutations Sentence Comment
55 ABCG2 p.Arg482Thr
X
ABCG2 p.Arg482Thr 23586520:55:100
status: NEW
view ABCG2 p.Arg482Thr details
ABCG2 p.Arg482Gly
X
ABCG2 p.Arg482Gly 23586520:55:91
status: NEW
view ABCG2 p.Arg482Gly details
For example, doxorubicin, rhodamine 123 and LysoTracker Green are substrates of the mutant R482G or R482T, but cannot be efficiently transported by wild-type BCRP [23-25]. Login to comment