ABCMdb

PMID: 22853952

Ramachandran S, Karp PH, Jiang P, Ostedgaard LS, Walz AE, Fisher JT, Keshavjee S, Lennox KA, Jacobi AM, Rose SD, Behlke MA, Welsh MJ, Xing Y, McCray PB Jr
A microRNA network regulates expression and biosynthesis of wild-type and DeltaF508 mutant cystic fibrosis transmembrane conductance regulator.
Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13362-7. doi: 10.1073/pnas.1210906109. Epub 2012 Aug 1., [PubMed]

Sentences

No. Mutations Sentence Comment

110 ABCC7 p.Gln493* ABCC7 p.Ser912* We also expressed a recombinant CMV promoter-driven CFTR-ƊF508 cDNA in primary human CFTR null airway epithelia (CFTR Q493X/S912X) using an adenovirus (Ad) vector (41). Login to comment 111 ABCC7 p.Gln493* ABCC7 p.Ser912* We also expressed a recombinant CMV promoter-driven CFTR-ΔF508 cDNA in primary human CFTR null airway epithelia (CFTR Q493X/S912X) using an adenovirus (Ad) vector (41). Login to comment 159 ABCC7 p.Gln493* ABCC7 p.Ser912* (A) (Upper) CFTR protein abundance from airway epithelia (CFTR Q493X/ S912X, 24-1 antibody) after indicated treatments. Login to comment 161 ABCC7 p.Gln493* ABCC7 p.Ser912* (A) (Upper) CFTR protein abundance from airway epithelia (CFTR Q493X/ S912X, 24-1 antibody) after indicated treatments. Login to comment 171 ABCC7 p.Arg1162* ƊF/* denotes ƊF508/3659delC; ƊF/** denotes ƊF508/R1162X. Login to comment 173 ABCC7 p.Arg1162* ΔF/* denotes ΔF508/3659delC; ΔF/** denotes ΔF508/R1162X. Login to comment