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PMID: 22614107
Sun YL, Kathawala RJ, Singh S, Zheng K, Talele TT, Jiang WQ, Chen ZS
Zafirlukast antagonizes ATP-binding cassette subfamily G member 2-mediated multidrug resistance.
Anticancer Drugs. 2012 Sep;23(8):865-73.,
[PubMed]
Sentences
No.
Mutations
Sentence
Comment
102
ABCG2 p.Arg482Thr
X
ABCG2 p.Arg482Thr 22614107:102:84
status:
NEW
view ABCG2 p.Arg482Thr details
ABCG2 p.Arg482Gly
X
ABCG2 p.Arg482Gly 22614107:102:74
status:
NEW
view ABCG2 p.Arg482Gly details
Therefore, we also examined the reversal effect of zafirlukast on mutant (
R482G
and
R482T
) ABCG2-overexpressing cells.
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