PMID: 22549112

Wang F, Mi YJ, Chen XG, Wu XP, Liu Z, Chen SP, Liang YJ, Cheng C, To KK, Fu LW
Axitinib targeted cancer stemlike cells to enhance efficacy of chemotherapeutic drugs via inhibiting the drug transport function of ABCG2.
Mol Med. 2012 Jul 18;18(1):887-98. doi: 10.2119/molmed.2011.00444., [PubMed]
Sentences
No. Mutations Sentence Comment
29 ABCG2 p.Arg482Thr
X
ABCG2 p.Arg482Thr 22549112:29:44
status: NEW
view ABCG2 p.Arg482Thr details
ABCG2 p.Arg482Gly
X
ABCG2 p.Arg482Gly 22549112:29:54
status: NEW
view ABCG2 p.Arg482Gly details
 MCF7/AdVp3000 and S1-M1-80 cells expressing R482T and R482G variants of BCRP/ABCG2, respectively, transported rhodamine 123 and Dox while also maintaining their ability to transport mitoxantrone (16,17). Login to comment