PMID: 21605668

Munic V, Hlevnjak M, Erakovic Haber V
Characterization of rhodamine-123, calcein and 5(6)-carboxy-2',7'-dichlorofluorescein (CDCF) export via MRP2 (ABCC2) in MES-SA and A549 cells.
Eur J Pharm Sci. 2011 Aug 17;43(5):359-69. doi: 10.1016/j.ejps.2011.05.003. Epub 2011 May 14., [PubMed]
Sentences
No. Mutations Sentence Comment
273 ABCG2 p.Arg482Thr
X
ABCG2 p.Arg482Thr 21605668:273:34
status: NEW
view ABCG2 p.Arg482Thr details
ABCG2 p.Arg482Gly
X
ABCG2 p.Arg482Gly 21605668:273:43
status: NEW
view ABCG2 p.Arg482Gly details
 However, only BCRP with mutations R482T or R482G transports rhodamine-123, and this transport can be inhibited with 10 lM fumitremorgin C (Honjo et al., 2001). Login to comment