ABCMdb

PMID: 18499536

Visca A, Bishop CT, Hilton SC, Hudson VM
Improvement in clinical markers in CF patients using a reduced glutathione regimen: an uncontrolled, observational study.
J Cyst Fibros. 2008 Sep;7(5):433-6. Epub 2008 May 21., [PubMed]

Sentences

No. Mutations Sentence Comment

43 ABCC7 p.Gly1244Glu ABCC7 p.Arg347Pro ABCC7 p.Gly542* ABCC7 p.Trp1282Gly 65 64 71 28.5 28 30 9 5 6 PA PA none 3, F, 19 DF508/G1244E 47 48 55 43 43 48 3 3 9 PA b PAb PA 4, M, 5 DF508/R347P NA NA NA 17 17.5 19 33 33 40 SA SA none 5, M, 24 W1282G/G542X 60 58 70 51 51.5 57 3 3 7 BC BC BC 6, F, 14 3659delC/? Login to comment 44 ABCC7 p.Gly1244Glu ABCC7 p.Tyr1182* 70 71 72 42 42 49 20 17 41 none SA none 7, F, 8 DF508/DF508 66 66 69 21 20.5 23 12 6 14 SA SA,H none 8, F, 7 Y1182X/G1244E 73 72 75 21 20.5 21.5 35 23 21 none none none 9, M, 27 DF508/2183delAA 38 38 44 53 53 58.5 3 3 10 PA b PAb SA 10, M, 22 2183delAA/? Login to comment 45 ABCC7 p.Arg347His 24 25 29 57 57 60.5 7 7 15 AX AX AX 11, M, 15 DF508/R347H 42 44 51 50.5 50 54 30 24 32 PA SA,PA none 12, M, 1 NA NA NA NA 10 10 12 9 5 25 NA NA NA 13, F, 1 DF508/DF508 NA NA NA 7.5 8 9.5 0 0 3 NA NA NA NA - data not available. T3 - 3 months prior to baseline; T0 - baseline; T5.5 - 5.5 months after baseline. Login to comment 64 ABCC7 p.Gly1244Glu ABCC7 p.Arg347Pro ABCC7 p.Gly542* ABCC7 p.Trp1282Gly 15.1 15.3 1 0 36 30 3, F, 19 DF508/G1244E 16.3 18.3 0 0 9 18 4, M, 5 DF508/R347P 14.7 15.4 0 1 11 11 5, M, 24 W1282G/G542X 17.8 19.7 1 0 16 20 6, F, 14 3659delC/? Login to comment 65 ABCC7 p.Gly1244Glu ABCC7 p.Tyr1182* 16.6 19.3 0 0 22 22 7, F, 8 DF508/DF508 14.0 15.0 2 1 34 14 8, F, 7 Y1182X/G1244E 15.5 15.7 0 0 28 20 9, M, 27 DF508/2183delAA 18.1 20.0 3 1 48 31 10, M, 22 2183delAA/? Login to comment 66 ABCC7 p.Arg347His 18.8 20.0 2 0 35 22 11, M, 15 DF508/R347H 17.5 18.7 1 1 10 18 12, M, 1 NA NA NA NA NA NA NA 13, F, 1 DF508/DF508 NA NA NA NA NA NA NA - data not available. T3 - 3 months prior to baseline; T0 - baseline; T5.5 - 5.5 months after baseline. Login to comment