PMID: 17979803

Saito H, Hirano H, Ishikawa T
High-speed screening and quantitative SAR analysis of human ABC transporter ABCG2 for molecular modeling of anticancer drugs to circumvent multidrug resistance.
Mini Rev Med Chem. 2007 Oct;7(10):1009-18., [PubMed]
Sentences
No. Mutations Sentence Comment
50 ABCG2 p.Arg482Thr
X
ABCG2 p.Arg482Thr 17979803:50:81
status: VERIFIED
view ABCG2 p.Arg482Thr details
ABCG2 p.Arg482Gly
X
ABCG2 p.Arg482Gly 17979803:50:71
status: VERIFIED
view ABCG2 p.Arg482Gly details
The wild type of ABCG2 transports MTX, whereas acquired mutants, i.e., R482G and R482T, do not [15]. Login to comment