PMID: 15509712

Pleban K, Kopp S, Csaszar E, Peer M, Hrebicek T, Rizzi A, Ecker GF, Chiba P
P-glycoprotein substrate binding domains are located at the transmembrane domain/transmembrane domain interfaces: a combined photoaffinity labeling-protein homology modeling approach.
Mol Pharmacol. 2005 Feb;67(2):365-74. Epub 2004 Oct 27., [PubMed]
Sentences
No. Mutations Sentence Comment
255 ABCB1 p.Ala935Cys
X
ABCB1 p.Ala935Cys 15509712:255:115
status: NEW
view ABCB1 p.Ala935Cys details
ABCB1 p.Ala935Cys
X
ABCB1 p.Ala935Cys 15509712:255:133
status: NEW
view ABCB1 p.Ala935Cys details
ABCB1 p.Leu138Cys
X
ABCB1 p.Leu138Cys 15509712:255:126
status: NEW
view ABCB1 p.Leu138Cys details
 With respect to putative TMs 2 and 11, cross-links were found for the double-cysteine mutants Val133/Gly939, C137C/A935C, and L138C/ A935C. Login to comment