ABCB1 p.Leu138Cys

Predicted by SNAP2: A: N (57%), C: N (78%), D: D (71%), E: D (59%), F: N (78%), G: D (59%), H: N (57%), I: N (87%), K: D (59%), M: N (93%), N: D (59%), P: D (71%), Q: N (57%), R: N (66%), S: N (78%), T: N (82%), V: N (87%), W: N (57%), Y: N (78%),
Predicted by PROVEAN: A: D, C: D, D: D, E: D, F: D, G: D, H: D, I: N, K: D, M: N, N: D, P: D, Q: D, R: D, S: D, T: D, V: N, W: D, Y: D,

[switch to compact view]
Comments [show]
Publications
[hide] Loo TW, Clarke DM
The packing of the transmembrane segments of human multidrug resistance P-glycoprotein is revealed by disulfide cross-linking analysis.
J Biol Chem. 2000 Feb 25;275(8):5253-6., 2000-02-25 [PMID:10681495]

Abstract [show]
Comments [show]
Sentences [show]

[hide] Loo TW, Bartlett MC, Clarke DM
Val133 and Cys137 in transmembrane segment 2 are close to Arg935 and Gly939 in transmembrane segment 11 of human P-glycoprotein.
J Biol Chem. 2004 Apr 30;279(18):18232-8. Epub 2004 Jan 28., 2004-04-30 [PMID:14749322]

Abstract [show]
Comments [show]
Sentences [show]

[hide] Pleban K, Kopp S, Csaszar E, Peer M, Hrebicek T, Rizzi A, Ecker GF, Chiba P
P-glycoprotein substrate binding domains are located at the transmembrane domain/transmembrane domain interfaces: a combined photoaffinity labeling-protein homology modeling approach.
Mol Pharmacol. 2005 Feb;67(2):365-74. Epub 2004 Oct 27., [PMID:15509712]

Abstract [show]
Comments [show]
Sentences [show]