PMID: 15358638

Zaman MM, Gelrud A, Junaidi O, Regan MM, Warny M, Shea JC, Kelly C, O'Sullivan BP, Freedman SD
Interleukin 8 secretion from monocytes of subjects heterozygous for the deltaF508 cystic fibrosis transmembrane conductance regulator gene mutation is altered.
Clin Diagn Lab Immunol. 2004 Sep;11(5):819-24., [PubMed]
Sentences
No. Mutations Sentence Comment
25 ABCC7 p.Gly551Asp
X
ABCC7 p.Gly551Asp 15358638:25:137
status: NEW
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 A similar hypersensitivity to LPS-induced induction of TNF-␣ mRNA has been shown in cultured bone marrow-derived macrophages from G551D CF mice (22). Login to comment 49 ABCC7 p.Trp1282*
X
ABCC7 p.Trp1282* 15358638:49:168
status: NEW
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ABCC7 p.Asn1303Lys
X
ABCC7 p.Asn1303Lys 15358638:49:153
status: NEW
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ABCC7 p.Cys276*
X
ABCC7 p.Cys276* 15358638:49:161
status: NEW
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 Although the majority of CF subjects were homozygous for ⌬F508, mutations on the other allele (compound heterozygotes) included 621 ϩ 1G-T, N1303K, C276X, W1282X, and 1717-1GϾA. Login to comment