PMID: 14973083

Ee PL, Kamalakaran S, Tonetti D, He X, Ross DD, Beck WT
Identification of a novel estrogen response element in the breast cancer resistance protein (ABCG2) gene.
Cancer Res. 2004 Feb 15;64(4):1247-51., 2004-02-15 [PubMed]
Sentences
No. Mutations Sentence Comment
15 ABCG2 p.Arg482Thr
X
ABCG2 p.Arg482Thr 14973083:15:39
status: VERIFIED
view ABCG2 p.Arg482Thr details
ABCG2 p.Arg482Gly
X
ABCG2 p.Arg482Gly 14973083:15:49
status: VERIFIED
view ABCG2 p.Arg482Gly details
 Cells that overexpress a mutated BCRP (R482T and R482G) remained sensitive to methotrexate (10-12). Login to comment