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PMID: 12535572
Schinkel AH, Jonker JW
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.
Adv Drug Deliv Rev. 2003 Jan 21;55(1):3-29., 2003-01-21
[PubMed]
Sentences
No.
Mutations
Sentence
Comment
387
ABCG2 p.Arg482Thr
X
ABCG2 p.Arg482Thr 12535572:387:33
status:
NEW
view ABCG2 p.Arg482Thr details
ABCG2 p.Arg482Gly
X
ABCG2 p.Arg482Gly 12535572:387:43
status:
NEW
view ABCG2 p.Arg482Gly details
We recently found that Ko134 has
R482T
and
R482G
mutants efficiently extruded all low cytotoxicity in vitro and that it can be given at three compounds [14].
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