ABCB1 p.Gly141Val

Predicted by SNAP2: A: N (78%), C: D (66%), D: D (75%), E: D (59%), F: D (80%), H: D (66%), I: D (75%), K: D (85%), L: D (75%), M: D (75%), N: D (71%), P: D (71%), Q: D (75%), R: D (85%), S: N (72%), T: N (66%), V: N (61%), W: D (85%), Y: D (80%),
Predicted by PROVEAN: A: N, C: D, D: D, E: D, F: D, H: D, I: D, K: D, L: D, M: D, N: D, P: D, Q: D, R: D, S: N, T: D, V: D, W: D, Y: D,

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Publications
[hide] Loo TW, Clarke DM
Rapid purification of human P-glycoprotein mutants expressed transiently in HEK 293 cells by nickel-chelate chromatography and characterization of their drug-stimulated ATPase activities.
J Biol Chem. 1995 Sep 15;270(37):21449-52., 1995-09-15 [PMID:7665554]

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[hide] Shilling RA, Venter H, Velamakanni S, Bapna A, Woebking B, Shahi S, van Veen HW
New light on multidrug binding by an ATP-binding-cassette transporter.
Trends Pharmacol Sci. 2006 Apr;27(4):195-203. Epub 2006 Mar 20., [PMID:16545467]

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[hide] Hrycyna CA
Molecular genetic analysis and biochemical characterization of mammalian P-glycoproteins involved in multidrug resistance.
Semin Cell Dev Biol. 2001 Jun;12(3):247-56., [PMID:11428917]

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[hide] Ueda K, Taguchi Y, Morishima M
How does P-glycoprotein recognize its substrates?
Semin Cancer Biol. 1997 Jun;8(3):151-9., [PMID:9441945]

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[hide] Senior AE, al-Shawi MK, Urbatsch IL
The catalytic cycle of P-glycoprotein.
FEBS Lett. 1995 Dec 27;377(3):285-9., [PMID:8549739]

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